Exploring the role of T cells in Alzheimer's disease, suggests new treatment strategies

Published Date: 10 Mar 2023

Nearly two dozen clinical trials targeting the immune system are in clinical trials for Alzheimer's disease.

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Targeted Therapy Tied to Less Severe Auditory Hallucinations

Targeted interventions, especially avatar therapy, are associated with less severe auditory hallucinations in patients with schizophrenia, a new meta-analysis shows.

Novel, Adaptive DBS Tied to Fewer Falls in Parkinson’s

In a small feasibility study, a novel adaptive DBS system synchronized with the walking cycle has been shown to reduce the risk for falls among patients with Parkinson’s disease.

ECT Tied to Delayed Schizophrenia Rehospitalizations

Electroconvulsive therapy (ECT) is associated with longer time to hospital readmission or suicide compared to non-ECT treatment in patients with schizophrenia, a study shows.

Sleep Disorders May Raise Risk for Sudden Death in Epilepsy

Comorbid primary sleep disorders are tied to higher risk for sudden unexpected death, all-cause mortality, and accidents in patients with epilepsy, a new study finds.

Transcranial Stimulation Shows Promise for Teen Self-Injury

For adolescents with depression and nonsuicidal self-injury, high-intensity transcranial alternating current stimulation improved emotion regulation, reduced attention to self-injury cues, and eased depressive symptoms in a proof-of-concept trial.

Can Treating Prodromal MS Delay or Prevent Disease Onset?

Researchers are investigating whether treating prodromal symptoms that precede radiologically isolated syndrome can delay or prevent disease onset.

Todays Updates

Ocular Motor Cranial Neuropathy Tied to Parkinson’s Disease

Ocular motor cranial neuropathy is associated with an increased risk for Parkinson’s disease, a new study shows.

TBI Shows Two-Way Association With Neurologic Conditions

Traumatic brain injury is bidirectionally associated with the incidence of stroke, dementia, epilepsy, and Parkinson’s disease, a retrospective study shows.

Pediatric Cancer in the 2000s: Uneven Survival Gains Seen

A large database study found overall 5- and 10-year improvement in pediatric cancer survival, but some cancers lag others, and demographic factors seem to influence trends.

Rheumatologist Shortage to Hit Nonmetropolitan Areas Hardest

Workforce projections show an uneven distribution of rheumatologists in the US, with notable shortages in nonmetropolitan areas and certain states and districts.

Epcoritamab Shows Promise in Frail Older Adults With LBCL

A phase 2 trial assesses fixed-duration epcoritamab monotherapy as first-line therapy for frail older adults with newly diagnosed anthracycline-ineligible large B-cell lymphoma.

NHS Extends RSV Jab to At-Risk Adults Aged 65-74

All adults aged 65-74 with a chronic respiratory condition or a weakened immune system will be offered the RSV vaccine from September, NHS England has confirmed.

Coffee and the Gut: What’s Brewing in the Microbiome?

Emerging evidence suggests coffee influences gut microbiota through bioactive compounds beyond caffeine, with potential effects on digestive and metabolic health.

Todays Updates

Ocular Motor Cranial Neuropathy Tied to Parkinson’s Disease

Ocular motor cranial neuropathy is associated with an increased risk for Parkinson’s disease, a new study shows.

TBI Shows Two-Way Association With Neurologic Conditions

Traumatic brain injury is bidirectionally associated with the incidence of stroke, dementia, epilepsy, and Parkinson’s disease, a retrospective study shows.

Pediatric Cancer in the 2000s: Uneven Survival Gains Seen

A large database study found overall 5- and 10-year improvement in pediatric cancer survival, but some cancers lag others, and demographic factors seem to influence trends.

Rheumatologist Shortage to Hit Nonmetropolitan Areas Hardest

Workforce projections show an uneven distribution of rheumatologists in the US, with notable shortages in nonmetropolitan areas and certain states and districts.

Epcoritamab Shows Promise in Frail Older Adults With LBCL

A phase 2 trial assesses fixed-duration epcoritamab monotherapy as first-line therapy for frail older adults with newly diagnosed anthracycline-ineligible large B-cell lymphoma.

NHS Extends RSV Jab to At-Risk Adults Aged 65-74

All adults aged 65-74 with a chronic respiratory condition or a weakened immune system will be offered the RSV vaccine from September, NHS England has confirmed.

Coffee and the Gut: What’s Brewing in the Microbiome?

Emerging evidence suggests coffee influences gut microbiota through bioactive compounds beyond caffeine, with potential effects on digestive and metabolic health.

Latest News

Targeted interventions, especially avatar therapy, are associated with less severe auditory hallucinations in patients with schizophrenia, a new meta-analysis shows.

In a small feasibility study, a novel adaptive DBS system synchronized with the walking cycle has been shown to reduce the risk for falls among patients with Parkinson’s disease.

Electroconvulsive therapy (ECT) is associated with longer time to hospital readmission or suicide compared to non-ECT treatment in patients with schizophrenia, a study shows.

Comorbid primary sleep disorders are tied to higher risk for sudden unexpected death, all-cause mortality, and accidents in patients with epilepsy, a new study finds.

For adolescents with depression and nonsuicidal self-injury, high-intensity transcranial alternating current stimulation improved emotion regulation, reduced attention to self-injury cues, and eased depressive symptoms in a proof-of-concept trial.

Researchers are investigating whether treating prodromal symptoms that precede radiologically isolated syndrome can delay or prevent disease onset.

News All Time

Lumateperone Linked to Lower Risk for Schizophrenia Relapse

Lumateperone was associated with a 63% lower risk for relapse and was well-tolerated among patients with schizophrenia.

CMS Rule Misses Mark on CPAP Adherence

A Kaiser Permanente study shows some people who initially struggle with CPAP adherence still use the device at 1 year, suggesting CMS’ 90-day cutoff is too strict.

New Imaging Agent Could Speed Detection of AD-Related Tau

A novel PET imaging agent identified AD-related tau earlier and in more patients than the currently used tracer, possibly speeding AD detection, a new study shows.

Federally Funded Research Backs Tighter Drinking Limits

A federally funded review conducted to inform US dietary advice supports a one-drink-per-day limit for all adults — a stricter recommendation than current federal guidance.

Melatonin Gummies Blur Line Between Medicine and Candy

Pediatricians call for a ban on melatonin gummy bears and similar products, warning that candy-like supplements may encourage unsupervised use in children.

A New Option for Headache?

Findings come from a single-center study suggest the non-opioid suzetrigine may help reduce pain in multiple headache types, but more research is needed.

NfL a Biomarker for Cognitive Function in Patients With MS?

New data offer strong evidence that neurofilament light chain (NfL) levels could be an accurate biomarker for monitoring cognitive function in MS.

Most ‘Sleep-Divorced’ Couples Support Sleeping Separately

A study in Brazil reveals the prevalence and attitudes among couples not driven by relationship stress toward ‘sleep divorce’ arrangements.

Experimental Drug Cuts Migraine Days in Mid-stage Trial

Denmark's Lundbeck said on Thursday its experimental drug bocunebart cut monthly migraine days in ⁠a mid-stage study, supporting further development of a new type of...

Spinal Cord Treatment Triggers Hope and Lawsuits in Brazil

An experimental treatment for spinal cord injuries is drawing patients from as far as Mexico, mobilizing the government to expedite approval before its safety has been proven in a clinical trial.

Global Lewy Body Dementia Incidence: New Data

The first known analysis of pooled worldwide population-based data on dementia with Lewy bodies shows incidence is higher than that of other uncommon neurological disorders.

Comorbid Illness Common in Functional Neurologic Disorder

Functional neurologic disorder has a higher mortality rate than multiple sclerosis and often occurs with comorbid neurologic and psychiatric disorders, a new study shows.

First Clear Win for BTK Inhibitors in Relapsing MS

After previous disappointments with BTK inhibitors, a novel drug in this class is the first to show superiority to an active comparator for relapsing MS outcomes.

Primary Care Making More Mental Health Diagnoses for Kids

Pediatric mental health visits in primary care surged over a 9-year period.

Electroacupuncture Promising for Cognitive Improvement in AD

Electroacupuncture was associated with long-term efficacy in improving cognitive function compared to sham treatment in patients with Alzheimer’s disease, a new trial shows.

Undiagnosed Dementia Tied to Increased Mortality Risk

Undiagnosed dementia is highly prevalent in the US and Brazil and is linked to increased 4-year mortality in both countries, a large cohort study shows.

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