Exploring the role of T cells in Alzheimer's disease, suggests new treatment strategies

Published Date: 10 Mar 2023

Nearly two dozen clinical trials targeting the immune system are in clinical trials for Alzheimer's disease.

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Fluctuations in Sleep Patterns Common in Schizophrenia

Variability in sleep efficiency and time in bed is increased in individuals at clinical high risk for psychosis or with schizophrenia spectrum disorders, new research shows.

Annual Wellness Visits May Help Flag Cognitive Issues

Annual wellness visits are linked to an increased chance of diagnosis of mild cognitive impairment.

Sleep Disorders Common in Medication Overuse Headache

Sleep disorders are more common in people with medication overuse headache than in those without the condition, with MOH treatment improving sleep, a study shows.

Psilocybin-Assisted Tx Shows Early Promise in Severe PTSD

Three quarters of veterans with severe, treatment-resistant PTSD achieve remission at 1 month after psilocybin-assisted therapy in a small pilot study.

Atogepant Outperforms Topiramate for Migraine Prevention

Atogepant shows better tolerability and efficacy than topiramate for migraine prevention in a phase 3b trial comparing the drugs.

Experimental Test Could Allow At-Home Autism Assessment

A novel adaptive test that quickly identifies autism with similar accuracy to conventional exams could soon be administered at home by parents in consultation with clinicians, a new study suggests.

Todays Updates

Prolonged Screen Time Linked to Sleep Issues in Preschoolers

Preschool-aged children exposed to screens for extended daily periods face elevated prevalence of sleep disturbances.

US Mental Health Treatment Rates Rise But Gaps Persist

Treatment rates for US adults with psychiatric disorders are modestly higher than in previous decades, but only a third receive minimally adequate care, new research shows.

Cognitive Bias Modification App Fosters Alcohol Avoidance

An Australian-designed smartphone app uses personalized cognitive bias modification to help users reduce or avoid alcohol consumption.

OA Tied to Arthritis AE Risk in ICI-Treated Patients

In patients with cancer receiving immune checkpoint inhibitor therapy, osteoarthritis is linked to the risk for inflammatory arthritis immune-related adverse events.

Stem Cell Transplant Linked to Longer Survival in CMML

Researchers evaluate the impact of allogeneic stem cell transplantation in chronic myelomonocytic leukemia across BLAST and BLAST-Mol clinical risk models.

Todays Updates

Prolonged Screen Time Linked to Sleep Issues in Preschoolers

Preschool-aged children exposed to screens for extended daily periods face elevated prevalence of sleep disturbances.

US Mental Health Treatment Rates Rise But Gaps Persist

Treatment rates for US adults with psychiatric disorders are modestly higher than in previous decades, but only a third receive minimally adequate care, new research shows.

Cognitive Bias Modification App Fosters Alcohol Avoidance

An Australian-designed smartphone app uses personalized cognitive bias modification to help users reduce or avoid alcohol consumption.

OA Tied to Arthritis AE Risk in ICI-Treated Patients

In patients with cancer receiving immune checkpoint inhibitor therapy, osteoarthritis is linked to the risk for inflammatory arthritis immune-related adverse events.

Stem Cell Transplant Linked to Longer Survival in CMML

Researchers evaluate the impact of allogeneic stem cell transplantation in chronic myelomonocytic leukemia across BLAST and BLAST-Mol clinical risk models.

Latest News

Variability in sleep efficiency and time in bed is increased in individuals at clinical high risk for psychosis or with schizophrenia spectrum disorders, new research shows.

Annual wellness visits are linked to an increased chance of diagnosis of mild cognitive impairment.

Sleep disorders are more common in people with medication overuse headache than in those without the condition, with MOH treatment improving sleep, a study shows.

Three quarters of veterans with severe, treatment-resistant PTSD achieve remission at 1 month after psilocybin-assisted therapy in a small pilot study.

Atogepant shows better tolerability and efficacy than topiramate for migraine prevention in a phase 3b trial comparing the drugs.

A novel adaptive test that quickly identifies autism with similar accuracy to conventional exams could soon be administered at home by parents in consultation with clinicians, a new study suggests.

News All Time

TBI History Tied to False-Negative Alzheimer’s Blood Test

FDA-approved p-tau217/amyloid-beta-42 testing missed more amyloid PET-positive cases among older adults with prior TBI, a cross-sectional cohort study shows.

p-Tau217 May Predict Cognitive Decline Years Before Symptoms

Higher plasma p-tau217 levels identified cognitively sound older adults at greater risk for future cognitive impairment up to a decade before symptom onset.

ENTF Stim Boosts Freedom From Disability Post-Stroke

Electromagnetic stimulation combined with physical and occupational therapy is linked to a higher rate of freedom from disability post-stroke than sham, a study shows.

Rituximab Noninferior to Ocrelizumab in Relapsing MS

Rituximab is noninferior to ocrelizumab in suppressing disease activity in newly diagnosed multiple sclerosis, with a similar incidence of adverse events, a new trial shows.

FDA Neurology Roundup: June 2026

A monthly snapshot of FDA activity involving therapies for the prevention and treatment of neurologic diseases.

AI Uncovers ‘Invisible’ Cortical Lesions in MS MRI Scans

AI-enhanced analysis of conventional MRI scans reveals thousands of hidden cortical lesions in multiple sclerosis, potentially opening a new window into disease progression.

Deep Brain Stimulation Tied to Lower Mortality in PD

Deep brain stimulation is linked to reduced risks for mortality and institutionalization, and lower healthcare costs in adults with Parkinson’s disease, a study shows.

Ask the IIM Experts: From Immune Mechanisms to Emerging Therapies - A Comprehensive Update on Idiopathic Inflammatory Myopathies

Ask the IIM Experts: From Immune Mechanisms to Emerging Therapies - A Comprehensive Update on Idiopathic Inflammatory Myopathies

What Is Causing This Case of Sudden Aphasia?

Clues come from a kidney injury, encephalop­athy, and drug dosing error

Neuropathy After Recreational Use of Laughing Gas

Clinicians should be aware of adverse effects of this increasingly popular drug

Alzheimer's Biomarkers Change After Tuberculosis Vaccination

BCG vaccine altered immune responses and modified amyloid-beta, study shows

Vitamin C and the Brain; Invisible MS Lesions Revealed; Profound Autism Definition

News and commentary from the world of neurology and neuroscience

Modified Amino Acid Improves Neurologic Symptoms in Rare Genetic Disorder

— Levacetylleucine succeeds in phase III trial of adults and kids with ataxia-telangiectasia

Third Molar Extraction: Benefit or Overtreatment?

Third molar removal may improve oral health markers, but its benefits must be weighed against surgical risks, postoperative morbidity, and cost.

Quick Case Challenge: Implementing FcRn Antagonists in gMG Practice

Quick Case Challenge: Implementing FcRn Antagonists in gMG Practice

Brain Risks Tied to High Ultraprocessed Food Intake

Longitudinal study links heavily processed food with a sharp increase in cognitive impairment

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