Creating a metabolic health blueprint for humans starting with mice.

Published Date: 12 Jun 2024

An unhealthy cholesterol level, elevated blood pressure, elevated blood sugar, and abdominal fat are among the risk factors that define metabolic syndrome (MetS). Heart disease risk is increased by these factors.

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Prior GLP-1 Use Doesn’t Affect Bariatric Surgery Results

Patients who have and have not had prior GLP-1 treatment show similar levels of weight loss with bariatric surgery.

Screening for Confidence Tailors GLP-1 Care

Perceived competence — not other factors — best distinguishes weight-loss success with GLP-1 treatment.

Amylyx Drug Cuts Low Blood Sugar Episodes in Bariatric Surgery Patients in Key Trial

Amylyx Pharmaceuticals' experimental drug sharply reduced dangerously low blood sugar episodes in a late-stage trial of patients who ⁠underwent weight-loss surgery, sending...

Diabetes Drug Curbs Weight Gain in Older People With HIV

Metformin, a common diabetes drug, curbs weight gain in older people with HIV over 96 weeks, but the effect reverses after treatment stops, a trial finds.

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Todays Updates

Belgian Algorithm Reshapes Endometrial Cancer Care

A new Belgian algorithm may help clinicians choose adjuvant therapy more precisely in early endometrial cancer, moving beyond TNM staging alone.

Latest News

Patients who have and have not had prior GLP-1 treatment show similar levels of weight loss with bariatric surgery.

Perceived competence — not other factors — best distinguishes weight-loss success with GLP-1 treatment.

Amylyx Pharmaceuticals' experimental drug sharply reduced dangerously low blood sugar episodes in a late-stage trial of patients who ⁠underwent weight-loss surgery, sending...

Metformin, a common diabetes drug, curbs weight gain in older people with HIV over 96 weeks, but the effect reverses after treatment stops, a trial finds.

A meta-analysis finds no significant association between use of semaglutide and risk for depression, although with limited certainty of evidence.

Gastroenterologist Byron L. Cryer, MD, discusses mentorship, NSAID research, difficult patient conversations, and why access to care remains a pressing challenge.

News All Time

T2D Medication Patterns Vary by A1c Levels

Type 2 diabetes medication adjustments in older adults vary by A1c levels.

US Bars Federal Funding Of Gender-affirming Care for Low-income Minors

The Trump administration finalized a rule on Tuesday barring two major federal health programs from funding puberty blockers, hormone therapy and surgeries to treat gender...

New Obesity Definitions Don’t Improve Liver Risk Prediction

New obesity definitions reclassify 20%-34% of patients with fatty liver disease into the obesity category, but it doesn’t increase their risk for liver-related events.

Harder Calorie Goal Yield More Weight Loss

A harder calorie goal — not a bigger step count, a shorter eating window, or stricter food rules — is associated with greater weight loss in adults with overweight or obesity.

These Two ‘Clock Genes’ May Influence Childhood Obesity

Kids with certain variants in genes regulating sleep and circadian rhythms might be more prone to overeating, new research suggests.

GLP-1s May Reduce Binge Eating

A systematic review and meta-analysis of randomized trials suggests that GLP-1s may reduce binge eating-related behaviors and emotional eating in people with overweight or obesity.

Start Bone-Saving Therapy as Weight Loss Journey Starts

PCPs 'have a duty' to remind patients about bone fragility that may come with weight loss without weight-bearing exercise.

7 Natural Ways to Suppress Appetite Now, and What’s Ahead

A majority of people manage their weight without a prescription drug, and natural strategies to curb appetite can help both them and those on medications.

Can BMI Normalization Reduce Progression to Type 1 Diabetes?

An observational study links BMI normalization to a lower risk for progression to stage 3 type 1 diabetes among autoantibody-positive individuals.

First Once-Weekly Basal Insulin Now Available in the US

The FDA approved Novo Nordisk's Awiqli for adults with type 2 diabetes in March 2026.

Manufacturing Issues Prevent GEP-NET Radioligand Approval

Maker says it's committed to resolving the issues and remains confident in ¹⁷⁷Lu-edotreotide.

Amazon Pharmacy Offers Weight-loss Drugs for $50 a Month Through Medicare Bridge Program

Amazon's pharmacy unit said on Thursday it would offer weight-loss drugs to eligible Medicare beneficiaries for $50 a ⁠month through a new federal program created to expand...

Semaglutide: A New Treatment Option for AUD?

Although it missed the primary endpoint, oral semaglutide significantly reduced heavy drinking days and several other alcohol-related outcomes in a phase 2 trial.

Automated Thoracic CT Scan Can Reliably Measure Bone Density

An automated framework for trabecular volumetric bone mineral density extraction from thoracic CT scans demonstrates reproducibility across various technical acquisition scenarios.

ATG Shows Real-Word Value for Early Type 1 Diabetes

The safety profile and C-peptide data support antithymocyte globulin as an alternative to teplizumab.

Immune Marker Curbs Starch Cravings After Bariatric Surgery

Changes in anti-inflammatory cytokine IL-10 levels can independently predict shifts in starchy food preferences after laparoscopic sleeve gastrectomy.

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