Diabetes is on the rise in children and young people

Published Date: 10 Mar 2023

New findings from researchers at Wake Forest University School of Medicine show that the rate of type 1 and type 2 diabetes is increasing...

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Inside the Major Findings From the NHS-Galleri Trial

The largest randomized study of a multicancer blood test found no reduction in late-stage cancers, while raising new questions about stage shift, mortality benefit, and population screening.

Talquetamab Combos Show Survival Benefit in r/r Myeloma

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Latest News

The anti-adrenocorticotropic hormone antibody asedebart normalized urinary free cortisol in 7 of 8 study participants.

Lifestyle changes, tracking, and support should go hand-in-hand with weight loss drugs.

An AI-based OCT system integrated into standard diabetic retinopathy screening pathways reduces unwarranted referrals for diabetic macular edema, a recent study shows.

Neumora Therapeutics will abandon the development of its experimental depression drug following the latest trial failures and ⁠said it would cut 35% of its workforce,...

Possible complications include adrenal insufficiency, hypogonadism, hyperprolactinemia, hospitalization, and mortality.

The drug was previously approved for stage 2 T1D.

News All Time

Older Drug Reprograms White Blood Cells, Improves Blood Sugar in Type 1 Diabetes

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays.)

Oral GLP-1 Orforglipron Performs Well in Phase 3 T2D Trials

Phase 3 trials of the oral nonpeptide show glycemic and weight benefit when added to glargine and compared with dapagliflozin and oral semaglutide, but with somewhat lower tolerability.

GLP-1s Tied to Musculoskeletal Benefits in Obesity

Use of GLP-1s vs other antiobesity medications is linked to decreased risk for osteoporosis, fractures, disk degeneration, and osteoarthritis in adults with obesity.

AI Tool Detects Occult Pancreatic Cancer Months in Advance

A new AI model reliably identifies hidden pancreatic ductal adenocarcinoma on routine CT scans months before the clinical diagnosis of the disease.

Use Of GLP-1 Drugs Early in Pregnancy Should Not Cause Alarm, Analysis Suggests

Use of GLP-1 drugs for diabetes or obesity early in the first trimester of pregnancy, before a woman realizes she is pregnant, is ⁠not a cause for alarm, a large new data...

Study Finds No Link Between Semaglutide and AMD Risk

Compared with other glucose-lowering drugs, semaglutide is not associated with the risk for neovascular age-related macular degeneration in adults with type 2 diabetes.

Can GLP-1s Curb Cancer Progression?

A real-world analysis links GLP-1s to substantially lower rates of metastatic progression in four cancers associated with obesity and/or diabetes — but experts urged caution to interpret the findings.

Skin Disorders in Transgender Patients: Treatment Tips

Dermatologists highlight the risks for acne, hair loss and unwanted hair, and melasma, as well as recent data on hidradenitis suppurativa.

Weekly and Monthly Berobenatide Show Weight, A1c Benefits

The long-acting GLP-1 drug had good overall tolerability with some GI bumps in weekly-to-monthly transition, while the A1c benefits raise hopes of a potential ‘game changer’ for T2D.

Roche Obesity Drug Helps Patients Shed 22.7% Of Weight in Mid-stage Trial

Roche said on Friday that patients lost 22.7% of their body weight in a mid-stage trial of its dual-acting experimental obesity ⁠drug, with more than a quarter of those who...

Wearables Generate the Data: What's Next for Chronic Care?

Wearable devices are moving beyond fitness tracking, providing clinicians with real-world data that may improve monitoring and continuity of care in chronic disease.

Beyond BMI: New Score Stratifies Obesity Risk

BMI, while useful, is insufficient to identify patients at the highest risk for obesity-related complications. A new tool may help clinicians better stratify risk and target treatment.

Tango Therapeutics' Pancreatic Cancer Drug Combo Shows Promise in Study

Tango Therapeutics said on Monday an experimental drug combination showed strong early results in a small study of patients ⁠with advanced pancreatic cancer and that it...

Liver-Directed Insulin: A New Way to Reduce Hypoglycemia?

Study findings suggest that a liver-targeted formulation of fast-acting insulin may reduce the risk for hypoglycemia in patients with type 1 diabetes.

Moving Beyond GLP-1s: Preclinical Acceleration, Innovation

Next-generation obesity therapeutics aim to counter weight rebound, decrease side effects, and support weight maintenance.

Dual Incretin Agonist Survodutide Benefits Liver in Phase 3

The glucagon receptor/GLP-1 receptor dual agonist reduces weight, visceral fat, and liver fat.

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