Diabetes is on the rise in children and young people

Published Date: 10 Mar 2023

New findings from researchers at Wake Forest University School of Medicine show that the rate of type 1 and type 2 diabetes is increasing...

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Multiple Myeloma Patients Have Unequal Access to Treatment

Lack of access to innovative and effective treatments compromises survival outcomes for many patients in Europe with multiple myeloma.

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A large study links the use of e-cigarettes after smoking cessation to higher lung cancer incidence and mortality than complete nicotine abstinence.

Combination Treatment May Improve Multiple Myeloma Outcomes

Post hoc analysis of the MajesTEC-3 trial shows the efficacy of the teclistamab plus daratumumab combination in hard-to-treat patients with high cytogenetic and functional risk.

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Latest News

Germany's government is replacing plans that would have introduced variable discounts on pharmaceuticals, ⁠a government source told Reuters on Monday, following opposition...

A systematic review finds no consistent adverse effects on the male hypothalamic-pituitary-gonadal axis and some evidence of fertility improvement with GLP-1 use.

Tirzepatide seems to activate brown adipose tissue, potentially modulating energy expenditure at the tissue level in premenopausal women with obesity.

Patients with primary and secondary empty sella show distinct clinical and endocrine trajectories over a median follow-up of about 5 years.

Tirzepatide treatment yields substantial weight loss and is well tolerated in patients with recurrent weight gain after bariatric procedures, a small real-world observational study finds.

In contrast to concerns of lean mass loss with GLP-1 receptor agonists, a large population-based study found lower fracture rates with semaglutide than with other weight-loss medications.

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Novo Nordisk Flags Patient Data Breach From Some Clinical Trials in Cyberattack

Novo Nordisk said on Thursday it has identified a security incident in which certain information, including ⁠patient data from some clinical trials, was copied externally...

Tirzepatide Outperforms Conventional Care in Early Diabetes

Tirzepatide offered better glycemic control and greater weight loss than intensive conventional care in adults with early type 2 diabetes, a study finds.

AI-Guided Prep Improves Bariatric Surgery Consults

A structured, AI-supported metacognitive framework substantially enhances the quality of metabolic and bariatric surgery consultations.

PMOS: Insulin Resistance Affects Fertility and Pregnancy

Prepregnancy insulin resistance is associated with impaired fertility and increased pregnancy complications such as preeclampsia.

Over-the-Counter CGM Okayed for Kids

The US FDA extended the age of use for Dexcom’s Stelo down to 2 years.

Novel Oral GLP-1 Shows A1c and Weight-Loss Benefits

The new drug would add another oral GLP-1 with no fasting or fluid intake restrictions to clinicians’ toolboxes, improving options for targeted treatment.

Older Drug Reprograms White Blood Cells, Improves Blood Sugar in Type 1 Diabetes

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays.)

Oral GLP-1 Orforglipron Performs Well in Phase 3 T2D Trials

Phase 3 trials of the oral nonpeptide show glycemic and weight benefit when added to glargine and compared with dapagliflozin and oral semaglutide, but with somewhat lower tolerability.

GLP-1s Tied to Musculoskeletal Benefits in Obesity

Use of GLP-1s vs other antiobesity medications is linked to decreased risk for osteoporosis, fractures, disk degeneration, and osteoarthritis in adults with obesity.

AI Tool Detects Occult Pancreatic Cancer Months in Advance

A new AI model reliably identifies hidden pancreatic ductal adenocarcinoma on routine CT scans months before the clinical diagnosis of the disease.

Use Of GLP-1 Drugs Early in Pregnancy Should Not Cause Alarm, Analysis Suggests

Use of GLP-1 drugs for diabetes or obesity early in the first trimester of pregnancy, before a woman realizes she is pregnant, is ⁠not a cause for alarm, a large new data...

Study Finds No Link Between Semaglutide and AMD Risk

Compared with other glucose-lowering drugs, semaglutide is not associated with the risk for neovascular age-related macular degeneration in adults with type 2 diabetes.

Can GLP-1s Curb Cancer Progression?

A real-world analysis links GLP-1s to substantially lower rates of metastatic progression in four cancers associated with obesity and/or diabetes — but experts urged caution to interpret the findings.

Skin Disorders in Transgender Patients: Treatment Tips

Dermatologists highlight the risks for acne, hair loss and unwanted hair, and melasma, as well as recent data on hidradenitis suppurativa.

Weekly and Monthly Berobenatide Show Weight, A1c Benefits

The long-acting GLP-1 drug had good overall tolerability with some GI bumps in weekly-to-monthly transition, while the A1c benefits raise hopes of a potential ‘game changer’ for T2D.

Roche Obesity Drug Helps Patients Shed 22.7% Of Weight in Mid-stage Trial

Roche said on Friday that patients lost 22.7% of their body weight in a mid-stage trial of its dual-acting experimental obesity ⁠drug, with more than a quarter of those who...

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