Diabetes is on the rise in children and young people

Published Date: 10 Mar 2023

New findings from researchers at Wake Forest University School of Medicine show that the rate of type 1 and type 2 diabetes is increasing...

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Machine Learning Model Boosts Genetic Prediction of T1D Risk

A machine learning model improves prediction of type 1 diabetes risk compared with a conventional genetic risk model, particularly in people without high-risk human leukocyte antigen haplotypes.

Rising, Falling Fat Mass Both Move Endotrophin Levels

Circulating endotrophin rises with fat gain and falls with fat loss, showing promise as a biomarker of body fat changes and a potential target for reducing obesity-linked health risks.

When Temperatures Climb, Hypoglycemia Risk Rises in T1D

An analysis of nearly 33 million continuous glucose monitoring readings links hotter temperatures to more frequent hypoglycemia in adults with type 1 diabetes.

Physical Activity Boosts Self-Esteem in Obesity

Women with obesity who completed supervised physical activity programs — whether face-to-face or digital — showed marked improvements in self-esteem and body image, with most gains emerging in the first month and persisting 3 months later.

Brazil Greenlights Five New Injectable Diabetes Drugs

Brazil's health regulator said ⁠it approved five new injectable GLP-1 drugs for diabetes and obesity treatment, ⁠following the expiration ⁠of Ozempic’s patent in ‌the country.

Statement Offers Guidance Around Incretin Prescribing

Consensus document from three European societies covers nutritional, functional, and psychological considerations for incretin-based therapies in adults.

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Residency Reverse: When the Patient's Home Is the Office

Home visits — once common and now resurging — flip the dynamic, as the clinician becomes a guest in the patient's home. Experts say as both learn more about each other than is possible in-office, trust can build.

Hidden Body Fat Threatens Male Fertility

Higher body fat percentage, rather than BMI, is associated with reduced sperm count and disrupted reproductive hormone levels in men.

The Dose Is Too High: Rethinking TKI Dosing

Standard TKI doses are often too high for long-term care. Dr Mark Kris shares his strategy for smart dose reductions that protect patient outcomes.

Optimizing Therapy in Early Stage HER2+ Breast Cancer

Cure rates are climbing, and so is the complexity of getting there. Dr Yara Abdou takes a closer look at optimizing HER2+ early-stage breast cancer therapy.

What I Wish I Knew Before Starting a Direct Primary Care

Direct primary care is more than medicine. Dr Rajdeep Dhami shares what physicians should know before starting DPC, from operations and branding to boundaries and community.

Todays Updates

Residency Reverse: When the Patient's Home Is the Office

Home visits — once common and now resurging — flip the dynamic, as the clinician becomes a guest in the patient's home. Experts say as both learn more about each other than is possible in-office, trust can build.

Hidden Body Fat Threatens Male Fertility

Higher body fat percentage, rather than BMI, is associated with reduced sperm count and disrupted reproductive hormone levels in men.

The Dose Is Too High: Rethinking TKI Dosing

Standard TKI doses are often too high for long-term care. Dr Mark Kris shares his strategy for smart dose reductions that protect patient outcomes.

Optimizing Therapy in Early Stage HER2+ Breast Cancer

Cure rates are climbing, and so is the complexity of getting there. Dr Yara Abdou takes a closer look at optimizing HER2+ early-stage breast cancer therapy.

What I Wish I Knew Before Starting a Direct Primary Care

Direct primary care is more than medicine. Dr Rajdeep Dhami shares what physicians should know before starting DPC, from operations and branding to boundaries and community.

Latest News

A machine learning model improves prediction of type 1 diabetes risk compared with a conventional genetic risk model, particularly in people without high-risk human leukocyte antigen haplotypes.

Circulating endotrophin rises with fat gain and falls with fat loss, showing promise as a biomarker of body fat changes and a potential target for reducing obesity-linked health risks.

An analysis of nearly 33 million continuous glucose monitoring readings links hotter temperatures to more frequent hypoglycemia in adults with type 1 diabetes.

Women with obesity who completed supervised physical activity programs — whether face-to-face or digital — showed marked improvements in self-esteem and body image, with most gains emerging in the first month and persisting 3 months later.

Brazil's health regulator said ⁠it approved five new injectable GLP-1 drugs for diabetes and obesity treatment, ⁠following the expiration ⁠of Ozempic’s patent in ‌the country.

Consensus document from three European societies covers nutritional, functional, and psychological considerations for incretin-based therapies in adults.

News All Time

Obesity Phenotype Predicts Tirzepatide Super Responders

Researchers identify a new subphenotype of obesity marked by fast gastric emptying, low GLP-1 levels, and greater postmeal hunger that is tied to substantially greater weight loss with tirzepatide.

Extreme Obesity Tied to Higher Mortality

The prevalence of obesity classes 4 and 5 in US adults has more than tripled since 2000, a study finds.

Short Stature: Is Genetic Testing Transforming Diagnosis?

A systematic review supports broader genetic testing for childhood short stature, helping clinicians replace idiopathic diagnoses with molecular causes.

Review of Exercise for Hip OA Suggests Minimal Benefits

Exercise vs no treatment/usual care may slightly reduce pain and improve physical function in adults with hip osteoarthritis, but the effects may not be clinically meaningful, per an updated review.

Thyroid Abnormalities Often Normalize in Pregnancy

Most pregnant women initially testing positive for subclinical hypothyroidism or hypothyroxinemia do not sustain abnormal thyroid function throughout pregnancy.

Protein, Not Calcium, Key to Osteoporosis Treatment Benefits

Calcium supplementation may not add to the benefits of osteoporosis medications in older women with adequate calcium intake, but a low protein intake is linked to attenuated effects.

Desire to Lose Weight Linked to Unhealthy Behaviors

More than 60% of American adults want to weigh less, and those who do are significantly more likely to skip meals, use non-prescription supplements, or engage in purging behaviors.

Obesity and Cognitive Problems: Understanding the Connection

One can lead to the other. There are a number of reasons why.

Diet Program May Not Match Knee Surgery in Knee OA & Obesity

In patients with obesity and knee osteoarthritis eligible for knee arthroplasty, an intensive dietary weight-loss program is clinically inferior to surgery for patient-reported pain and function.

Increasing GLP-1 Use Raises Muscle Loss Concerns

Incretin mimetic therapy for obesity may reduce muscle mass and bone mineral density, but its effects on physical function and the risk for fractures in older adults remain uncertain.

Spermidine Intake Tied to Liver Health in Obesity and MetS

An increase in dietary spermidine intake over 1 year is associated with improvements in hepatic function and cardiometabolic health in older adults with overweight or obesity and metabolic syndrome.

USG Detects Vagus Nerve Atrophy in Parkinson's Disease

Ultrasound imaging reveals structural changes in the vagus nerve of patients with Parkinson's disease in a meta-analysis.

SGLT2-GLP-1 Combo Little Better Than Monotherapy in T2D

Using both SGLT2 inhibitors and GLP-1 receptor agonists is no more effective than using either drug alone in patients with type 2 diabetes, a new meta-analysis suggests.

Mindfulness-Based Eating Improves Anxiety, Eating Behavior

A mindfulness-based eating intervention improved anxiety, depression, and eating behaviors in adults with obesity and generalized anxiety disorder.

5 Common Lab Results: Why Context Matters

Common laboratory tests can mislead when interpreted without clinical context, highlighting why appropriate test selection matters as much as the results themselves.

Lilly Announces More Next-gen Obesity Drug Data, Plans Q1 2027 FDA Application

Eli Lilly said on Thursday that two more Phase 3 trials of its experimental obesity drug retatrutide showed positive results and it plans to submit ⁠an application to the...

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