Diabetes is on the rise in children and young people

Published Date: 10 Mar 2023

New findings from researchers at Wake Forest University School of Medicine show that the rate of type 1 and type 2 diabetes is increasing...

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Lilly CEO Sees Weight-loss Drugs Reaching About Half Of Potential Users At Peak

Weight-loss drugs may eventually reach only about 50% of the overweight and obese people who could benefit from them due to complexities of healthcare systems ⁠and financial...

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Few patients with bloating experience symptoms from fermentable fibers, with predictors including a higher baseline symptom burden and distinct gut microbiome patterns.

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Latest News

Weight-loss drugs may eventually reach only about 50% of the overweight and obese people who could benefit from them due to complexities of healthcare systems ⁠and financial...

Avoidant/restrictive food intake disorder was inconsistently identified in patients with GI disorders, likely leading to overestimation of its prevalence.

Study on compounded GLP-1s uncovers use of additives and questionable sterility practices, revealing legally ‘murky’ area.

Although APOL1 variants are linked to kidney disease risk, the presence of the M1 genetic variant appears to reduce that risk.

A large NHANES analysis suggests that 7 hours of sleep may represent a metabolic sweet spot, whereas too little, too much, or excessive weekend catch-up sleep may worsen insulin resistance.

Few patients with bloating experience symptoms from fermentable fibers, with predictors including a higher baseline symptom burden and distinct gut microbiome patterns.

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Managing Care When Gender-Affirming Therapy Is Limited

As access to gender-affirming care for minors narrows, clinicians are adapting — using nonhormonal options, stronger mental health support, and creative, patient-centered strategies.

Postmenopausal HRT Tied to Glaucoma Risk in Women

The use of postmenopausal hormone replacement therapy is associated with an increased risk for glaucoma in Finnish women aged 50 years or older, according to a recent nested case-control study.

Novo Nordisk Launches Wegovy Subscription Program

The telehealth platform program saves money for some self-pay patients, but experts express concerns about fragmentation of care.

Incretin-Based Drugs Show Superior Glycemic Profiles on CGM

Continuous glucose monitoring in the GRADE trial shows that incretin-based drugs such as sitagliptin and liraglutide produce the most stable glycemic profiles and show the lowest hypoglycemia risk.

Recent Depression Tied to Treatment Intensification in T2D

Patients with T2D who have a history of depression, especially a recent episode, are more likely to undergo earlier treatment intensification and insulin initiation than those who do not.

US FDA Weighs Broader Use Of Testosterone Therapy for Low Sex Drive in Men

The U.S. Food and Drug Administration is considering approving testosterone replacement therapy ⁠to treat low sex drive in men whose bodies do not produce enough of ⁠the...

Tirzepatide Best for Weight Loss in Adults Without T2D

High doses of the dual agonist tirzepatide appear to provide greater weight loss than other GLP-1s among adults with overweight or obesity who don’t have type 2 diabetes.

Knee Osteoarthritis Pain Relief Seen With Neurotrophin-3 Inhibition

A p75 neurotrophin receptor fusion protein reduces pain and improves function in patients with knee osteoarthritis across all tested doses and shows favorable safety outcomes in a phase 2 trial.

How Limited Is Evidence for Preventing Nephrolithiasis?

A systematic review finds limited evidence that selected drugs and hydration may reduce the risk for kidney stone recurrence.

Can Genes Affect GLP-1 Side Effects and Treatment Outcomes?

Two genetic variants may help explain differences in side effects and weight loss in patients taking GLP-1 drugs.

Lower Albumin Levels Linked to Fracture Risk in Older Women

Lower levels of serum albumin and lower values of a nutrition-related index are associated with a higher risk for fracture in older women.

Revolution Medicines' Experimental Cancer Pill Boosts Survival in Late-stage Study

Revolution Medicines' experimental oral drug helped patients with pancreatic cancer live nearly twice as long as those treated ⁠with chemotherapy in a keenly anticipated...

SGLT2 Therapy Linked to Higher Ketoacidosis Risk in T2D

SGLT2 inhibitor therapy is linked to an increased risk for diabetic ketoacidosis in adults with T2D, particularly among those with elevated baseline A1c levels, a recent meta-analysis shows.

Fighting Outbreaks One Conversation at a Time

From Hackney to West Yorkshire, a GP and a public health researcher are tackling vaccine hesitancy by reaching the families mainstream messaging leaves behind.

Ginger Dietary Supplement May Ease GLP-1-Related Nausea

Primary endpoint didn’t reach significance, but secondary endpoints showed nausea reduction with herbal supplement from Dramamine maker.

FDA Requires Lilly to Conduct Post-marketing Studies for Obesity Pill

The ⁠U.S. Food and ⁠Drug Administration said ⁠Eli ‌Lilly is required to conduct post-marketing ‌trials to gauge risks ‌for ‌liver injury, cardiovascular ⁠events, ‌gastric...

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