Use of contrast material improves aortic valve assessment during echocardiography: a study

Published Date: 10 Mar 2023

United States: The US research team recommended using a different agent to enhance the Doppler profile for more accurate measurements.

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Perioperative Pain Management: A Narrative Review

Primary care practitioners are uniquely positioned to provide preoperative risk assessments for adverse postoperative acute pain outcomes.

Real-Time Ultrasound Boosts Epidural First-Pass Success Rate

Patients receiving real-time ultrasound guidance for thoracic epidural anesthesia during abdominal surgery have higher first-pass success rates than those with only preprocedural ultrasound marking.

How Can Pain Be Recognized When Words Fail?

Standard pain scales have limitations in patients who cannot communicate, and the inconsistent use of assessment tools may leave clinically important suffering unrecognized.

Hip Fracture, No Surgery? Phenol Block May Help Older Adults

Injecting phenol into the nerve group surrounding the hip capsule may offer some pain relief and mobility gains in older adults who are frail and forgo surgery for hip fracture.

Coma Therapy Tied to Poor Outcomes in Nonconvulsive SE

Patients with nonconvulsive status epilepticus treated with therapeutic coma experience markedly higher rates of complications and mortality than those not receiving the treatment.

Whole Person Approach to Pain Management for Vets in Hospice

This quality improvement project aims to support the uptake and utilization of nonpharmacological pain management interventions for veterans receiving inpatient hospice care.

Todays Updates

Osimertinib's OS Benefit in Resected NSCLC Persists 8 Years

Even years after treatment ends, adjuvant osimertinib brings an overall survival benefit to patients with resected EGFR-mutated lung cancer.

Pelvic RT Tied to Longer Survival in Cervical Cancer

In patients with newly diagnosed stage IVB cervical cancer, adding definitive-dose pelvic radiotherapy to chemotherapy was associated with longer survival compared with chemotherapy alone.

New Data Put ADCs on the Map in Relapsed SCLC

Two B7-H3-directed antibody-drug conjugates substantially improve survival over topotecan among patients with relapsed small cell lung cancer — pointing to a potential new treatment class.

Real-World Liso-Cel Results in MCL Consistent With Trials

Two analyses of liso-cel CAR T-cell therapy in relapsed or refractory mantle cell lymphoma show response rates in the real-world setting similar to those seen in clinical trial populations.

Antibiotic Use in Hospice Linked to Higher Mortality Risk

Antibiotic use in patients under hospice care is associated with an increased risk for mortality; for infectious hospice-qualifying conditions, antibiotic use is linked to extended survival.

Todays Updates

Osimertinib's OS Benefit in Resected NSCLC Persists 8 Years

Even years after treatment ends, adjuvant osimertinib brings an overall survival benefit to patients with resected EGFR-mutated lung cancer.

Pelvic RT Tied to Longer Survival in Cervical Cancer

In patients with newly diagnosed stage IVB cervical cancer, adding definitive-dose pelvic radiotherapy to chemotherapy was associated with longer survival compared with chemotherapy alone.

New Data Put ADCs on the Map in Relapsed SCLC

Two B7-H3-directed antibody-drug conjugates substantially improve survival over topotecan among patients with relapsed small cell lung cancer — pointing to a potential new treatment class.

Real-World Liso-Cel Results in MCL Consistent With Trials

Two analyses of liso-cel CAR T-cell therapy in relapsed or refractory mantle cell lymphoma show response rates in the real-world setting similar to those seen in clinical trial populations.

Antibiotic Use in Hospice Linked to Higher Mortality Risk

Antibiotic use in patients under hospice care is associated with an increased risk for mortality; for infectious hospice-qualifying conditions, antibiotic use is linked to extended survival.

Latest News

Primary care practitioners are uniquely positioned to provide preoperative risk assessments for adverse postoperative acute pain outcomes.

Patients receiving real-time ultrasound guidance for thoracic epidural anesthesia during abdominal surgery have higher first-pass success rates than those with only preprocedural ultrasound marking.

Standard pain scales have limitations in patients who cannot communicate, and the inconsistent use of assessment tools may leave clinically important suffering unrecognized.

Injecting phenol into the nerve group surrounding the hip capsule may offer some pain relief and mobility gains in older adults who are frail and forgo surgery for hip fracture.

Patients with nonconvulsive status epilepticus treated with therapeutic coma experience markedly higher rates of complications and mortality than those not receiving the treatment.

This quality improvement project aims to support the uptake and utilization of nonpharmacological pain management interventions for veterans receiving inpatient hospice care.

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Disposables Dominate Cesarean Anesthesia Carbon Footprint

Disposable items account for the majority of anesthesia-related carbon emissions during cesarean delivery, with a notable portion coming from products that are opened but discarded without use.

Poor Function Before ICU Admission Tied to Later Death Risk

Frailty and functional dependency before admission are associated with an increased risk for mortality after admission to the ICU, although the evidence remains uncertain.

Social Egg Freezing: Choice, Business, or Burden?

Growing interest in egg preservation raises questions about access, affordability, informed consent, and whether workplace pressures shift reproductive responsibility onto women.

‘No Cure’: What This Doctor Did When Her Own Health Imploded

She always wanted to be a strong doctor, but everything changed when this anesthesiologist realized the truth about her rare symptoms — and incurable condition.

Booming Weight-loss Drug Demand in Brazil Fuels Thriving Black Market and Health Fears

When Brazilian customs agents opened jars of dulce de leche aboard a tourist bus arriving from Paraguay in April, they discovered hundreds of vials of tirzepatide, the...

Watch Out! A Coding Audit May Be Coming Your Way

Payers are stepping up their audit activities for medical practice and hospital billing and coding. Here’s how to avoid being a target.

How Scrubs (and Time) Quietly Stole the White Coat’s Mojo

They began as plain operating-room clothes. Now scrubs are healthcare’s default uniform, a big business, and even runway inspiration. How did the white coat go out of style?

Beyond the Scale: Men Turn to Cosmetic Clinics to Complete Weight-loss Transformation

As top-selling weight-loss drugs help more U.S. men slim down, a growing number are seeking cosmetic treatments for sagging skin, hair loss and dental issues to complete...

Deep Dive: SNRIs: One Mechanism, No Interchangeability

Milnacipran and its enantiomer, levomilnacipran, share a mechanism but not one approved indication. Alan Schatzberg, MD, on what that split means for prescribing.

States Tighten Private Equity Healthcare Oversight

Nearly a dozen states have recently enacted laws addressing private equity in healthcare, including ownership transparency and physician control, with more bills pending.

Rewriting the Vaccine Schedule Without Science at the Table

Dr Daskalakis explains the confusion a recent executive order on vaccines can wrought, and why the MMR vaccine cannot simply be split into three shots.

Mental Health Burden High Among PWH in Panama

Nearly 1 in 6 people living with HIV report moderate-to-severe depression and nearly 1 in 5 report high anxiety — both tied to discrimination, chronic pain, and difficulty with daily activities.

Are GLP-1 Drugs Now Kidney Drugs?

We file GLP-1s under "diabetes drugs" or "weight-loss drugs." Both labels are true. But data from the last 24 months show that these are kidney drugs.

How to Discuss Postmastectomy Numbness in a 20-Minute Visit

Dr Kristin Rojas gives clinicians practical and actionable tips on how to discuss postmastectomy numbness and intimacy with patients.

Is Chronic Pain Guidance Delivering What NICE Promised?

Pain specialists say patients still aren’t getting what NICE’s guidance promised — and access remains the real barrier.

Deep Dive: DOACs in 2026: Why the Incumbents Still Win

Two trials tried to beat DOACs on bleeding. One (phase 3) failed on efficacy; the other (phase 2b) left stroke prevention unproven. John Alexander, MD, on what that means for practice.

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