Tracing a rare muscle disorder back to a mutation in a noncoding gene

Published Date: 02 Mar 2023

A research team from Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB) and Mass General for Children (MGfC), has identified a mutation in a non-first time.

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Northwestern Medicine scientists have uncovered how a specific type of cell in the inner ear plays a commanding role in shaping the cellular landscape of the organ responsible for hearing, according to a study published in ...

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Parents who struggle to identify emotions may face higher burnout, alexithymia study finds

Researchers at the Institute of Psychology at the Maria Grzegorzewska University in Warsaw report associations between alexithymia and parental burnout and sex-specific differences.

New screening tool helps identify emotional needs after childhood injuries

Injuries not only cause physical harm to children but can also present psychosocial challenges for pediatric patients and their families.

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Overall, 13.5% of U.S. children living in households receiving supplemental nutrition benefit programs have food insecurity (FI), according to a research brief published online Nov. 7 in Pediatrics.

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Todays Updates

Parents who struggle to identify emotions may face higher burnout, alexithymia study finds

Researchers at the Institute of Psychology at the Maria Grzegorzewska University in Warsaw report associations between alexithymia and parental burnout and sex-specific differences.

New screening tool helps identify emotional needs after childhood injuries

Injuries not only cause physical harm to children but can also present psychosocial challenges for pediatric patients and their families.

It's OK to walk away: The program saving babies' lives

Researchers invited to evaluate a U.K. program that aims to prevent shaken baby syndrome say the study offers insights that could inform support strategies for Australian parents and caregivers struggling with the stress ...

Food insecurity reported in 13.5% of US children in homes receiving benefits

Overall, 13.5% of U.S. children living in households receiving supplemental nutrition benefit programs have food insecurity (FI), according to a research brief published online Nov. 7 in Pediatrics.

Children's screen use tied to reduced attention, while reading boosts concentration

Children who use electronic media more frequently tend to show lower levels of attention, while independent reading is associated with better concentration. These are the findings of a survey of more than 1,000 children conducted ...

The surprising household items putting babies and toddlers at risk

You may think your home is safe once the outlet covers are in, the baby gates are locked and the sharp corners are padded, but some of the biggest dangers to babies and toddlers aren't the ones parents can see.

Temporal artery ultrasound in the real-time diagnosis of stroke of the eye

For most of us, the phrase "stroke of the eye" sounds like a metaphor. But for UK HealthCare's Jagannadha "Jay" Avasarala, M.D., Ph.D., it's a literal and urgent diagnosis—one that could mean the difference between sight ...

Latest News

Northwestern Medicine scientists have uncovered how a specific type of cell in the inner ear plays a commanding role in shaping the cellular landscape of the organ responsible for hearing, according to a study published in ...

An epigenetic factor that is essential for producing mature egg cells in mice has been identified by RIKEN researchers for the first time. This discovery could aid research into cases of infertility caused by immature eggs.

Differences between men and women in intelligence and behavior have been proposed and disputed for decades.

The human genome is riddled with relics of viral infections—bits of DNA from viruses that have been inserted in human DNA over millions of years and never left. Most are silent but some have taken on functional roles, particularly ...

Like the astronomical explosion that kickstarted the universe, bowel cancer has a "Big Bang" moment which determines how it will grow, according to new research.

NYU Langone Health researchers found that a type of cell death caused by a buildup of highly reactive molecules suppresses lung tumor growth.

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New clue to ALS and FTD: Faulty protein disrupts brain's 'brake' system

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BRCA2 research reveals a novel mechanism behind chemoresistance

One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.

Genetic mechanisms reveal how toxic substances damage balance cells in the inner ear

The vestibular system is responsible for the sense of balance in the inner ear. Prolonged use of toxic substances, such as certain antibiotics or anticancer drugs, can damage the hair cells that form part of this system, ...

Challenging conventional wisdom on a common cause of melanoma

University of Queensland researchers have found that a genetic mutation that causes melanoma can lie dormant in healthy skin, a finding that could improve screening of areas more prone to the disease.

Genes associated with obesity shared across ancestries, researchers find

Obesity is a global epidemic affecting millions of people every day and is associated with comorbidities ranging from heart disease and type 2 diabetes to osteoarthritis and social stigma. While lifestyle factors, like diet ...

Transcription factor drives chemotherapy resistance in ovarian cancer

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Heart 'blueprint' reveals origins of defects and insights into fetal development

New research in Sweden has produced a "blueprint" revealing how the human heart is built during prenatal development. It offers insights that could lead to improved prenatal care and new treatments for heart defects, such ...

Changing the 'packaging' of DNA in neurons can turn memories on or off in mice

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MAGIC: AI-assisted 'laser tag' illuminates cancer origins

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Additional testing of FISH-negative tests for renal cell carcinoma can improve kidney cancer diagnosis

A study from the University of Michigan Health Rogel Cancer Center and Department of Pathology shows that further testing in renal cell carcinoma with an overexpression of gene TRIM63 could uncover a mutation otherwise undetected, ...

Common genetic causes across motor neuron diseases identified

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct. However, an analysis led by investigators ...

Mutation yields hot new clues for treating immune 'cold' tumors

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3D genome mapping tool reveals hidden complexity in DNA

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Genetic variants can simultaneously increase BMI and lower cholesterol risk

Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high cholesterol, UTHealth Houston researchers discovered.

Oxygen deprivation heightens risk of illness by changing genes, researchers discover

Low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body's ability to fight infection, new research shows.

Previously unknown genetic cause of microcephaly identified

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay. An international research team led by Dr. Tran Tuoc from the Department of Human ...

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