7 mars 2023

Published Date: 10 Mar 2023

Today's top stories include: Nine-year cap to complete MBBS, elective-based credits offered in NMC letter Students enrolled in...

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Narrowing the Biological Age Gap Tied to Better Brain Health

Narrowing the gap between an individual’s biological and chronological age is linked to better brain health and a 23% reduced stroke risk, new research suggests.

Risk Score May Let Many With Chest Pain Skip Further Tests

The PROMISE minimal risk score identifies patients with recent-onset stable chest pain who can safely avoid extra testing and are less likely to have significant coronary disease or adverse events.

Cholesterol Guideline Emphasizes Earlier Treatment

A new cardiovascular calculator targeting individuals aged 30-79 years can help prevent atherosclerotic cardiovascular disease by estimating long-term risk for heart attack and stroke.

Frailty Index May Guide Blood Pressure Decision-Making

Frailty, rather than chronological age, more accurately distinguishes the ranges of systolic blood pressure that are linked to a lower risk for adverse cardiac events in patients with hypertension.

Antithrombotic Choice May Affect Bleed Risk in Endocarditis

The use of anticoagulation therapy at diagnosis of left-sided infective endocarditis may increase the risk for intracranial hemorrhage, especially when combined with antiplatelet therapy.

GLP-1 Drugs Show Benefits in Cushing Syndrome

GLP‑1 receptor agonists aid weight loss and improve glycaemic control and liver function in patients with Cushing syndrome and concurrent type 2 diabetes and/or obesity.

Todays Updates

Older Adults With Advanced Cancer Prioritize Quality of Life

Most older adults with advanced cancer value quality of life over extending survival, but that preference may not translate to clinical care or outcomes.

Todays Updates

Older Adults With Advanced Cancer Prioritize Quality of Life

Most older adults with advanced cancer value quality of life over extending survival, but that preference may not translate to clinical care or outcomes.

Latest News

Narrowing the gap between an individual’s biological and chronological age is linked to better brain health and a 23% reduced stroke risk, new research suggests.

The PROMISE minimal risk score identifies patients with recent-onset stable chest pain who can safely avoid extra testing and are less likely to have significant coronary disease or adverse events.

A new cardiovascular calculator targeting individuals aged 30-79 years can help prevent atherosclerotic cardiovascular disease by estimating long-term risk for heart attack and stroke.

Frailty, rather than chronological age, more accurately distinguishes the ranges of systolic blood pressure that are linked to a lower risk for adverse cardiac events in patients with hypertension.

The use of anticoagulation therapy at diagnosis of left-sided infective endocarditis may increase the risk for intracranial hemorrhage, especially when combined with antiplatelet therapy.

GLP‑1 receptor agonists aid weight loss and improve glycaemic control and liver function in patients with Cushing syndrome and concurrent type 2 diabetes and/or obesity.

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Fermented Dairy and Metabolic Syndrome: Sex-Specific Link

Different types of dairy products show sex-specific associations with metabolic syndrome and its components, such as levels of lipid markers, a new Finnish study shows.

Photon-Counting CT May Boost In-Stent Restenosis Diagnosis

Ultrahigh-resolution photon-counting detector CT can diagnose coronary in-stent restenosis with higher accuracy than standard-resolution reconstructions, a retrospective study shows.

Telemedicine Platform Yields Notable, Lasting Weight Loss

A real-world study finds that adults with obesity or overweight and related comorbidities who receive antiobesity medications through a telehealth clinic achieve substantial long-term weight loss.

Heart Scans Reveal Hidden Health Issues in Many Older Adults

Advanced heart scans and routine health checks reveal previously unknown heart and other health issues in a vast majority of older adults.

Can Medicine Make Us Live to 150?

Clinical advances in transplants, geroprotective drugs, and metabolomic clocks are shifting focus from lifespan to healthspan — but major biological and ethical limits remain.

Childhood Oral Health Linked to Cardiovascular Disease Later in Life

Kids with numerous dental problems and severe gingivitis were up to 45% more likely to have a heart attack, stroke, or coronary artery disease as adults than kids with less oral disease.

Semaglutide Boosts Insulin Sensitivity in Schizophrenia Care

Semaglutide can mitigate antipsychotic-induced metabolic dysfunction in patients with schizophrenia, prediabetes, and overweight or obesity on second-generation antipsychotics.

1 in 4 Kids at Juvenile Arthritis Onset Have Renal Issues

Acute kidney injury occurs in nearly one quarter of children at the onset of juvenile idiopathic arthritis and increases the risk for long-term kidney damage by more than five times.

VTE Trial: As DOACs Face Off, Apixaban Confirmed Safer

Apixaban halved the risk for bleeding compared with rivaroxaban in the treatment of acute venous thromboembolism in the randomized COBRRA trial.

New Non-Hormonal Menopause Drug Backed by NICE

NICE has recommended fezolinetant for menopausal hot flushes and night sweats, offering a non-hormonal option when HRT is unsuitable.

CV Risk Increased Across Spectrum of Primary Aldosteronism

Primary aldosteronism may influence cardiovascular risk, even at levels below current diagnostic thresholds in older adults.

Evidence Questions Routine Calcium Supplementation for Bones

Evidence from randomized trials suggests that calcium supplements may not significantly reduce fracture risk in well-nourished adults.

Primary Care for Kidney Failure Linked to Fewer ER Visits

Comprehensive care beyond dialysis is critical for patients with end-stage kidney disease.

Immunofitness: Vaccination for Healthy Aging

A Spanish review suggests vaccines — influenza, RSV, COVID, pneumococcal, zoster, and others — may help preserve immune function in older adults and reduce hospitalizations.

Beyond GLP-1s: Which Weight-Loss Drugs Are on the Way?

Pharmaceutical company investments in novel obesity treatments are soaring in 2026.

Rising Childhood Obesity: Implications for Clinicians

In Brazil, an estimated 6.6 million children aged 5-9 years and 9.9 million adolescents aged 10-19 years are overweight or have obesity; clinicians should prioritize prevention and early intervention.