7 mars 2023

Published Date: 10 Mar 2023

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Inflammation May Explain Link Between Belly Fat, HF

Excess abdominal fat — not overall body weight — may drive heart failure risk, with systemic inflammation being partially to blame.

In High-BP Patients, Lifestyle Tied to Cardiometabolic Risk

Maintaining a healthy lifestyle was associated with a lower risk for major cardiometabolic diseases, regardless of antihypertensive medication use.

Arterial Stiffness Changes Linked to Developing Dementia

Pulse wave velocity, calculated from age and blood pressure changes, was associated with significant dementia risk in a post hoc SPRINT analysis.

Tool Spots Heart Failure Risk Missed in Patients With ASCVD

A risk model predicts the risk for heart failure in patients with atherosclerotic cardiovascular disease and flags a notable proportion classified as low risk by other risk tools.

Triple Agonist Retatrutide Reduces A1c, Weight in T2D

Eli Lilly and Company report top-line phase 3 clinical trial results for its investigational GLP-1, GIP, and glucagon agonist in people with type 2 diabetes.

Are Nursing Homes Misprescribing Antipsychotics?

The HHS Inspector General claims that some nursing homes are inappropriately diagnosing residents with schizophrenia and prescribing antipsychotics without proper oversight.

Todays Updates

From Pathology to Precision: The Story of Leukemia Therapy

From 19th century ‘white blood’ observations and pathological anatomy to the discovery of BCR-ABL and imatinib, leukemia care evolved from near-certain death to precise, life-extending therapies.

Delaying Pegfilgrastim May Curb Bone Pain in Breast Cancer

Pegfilgrastim helps prevent myelosuppression in women undergoing chemotherapy for breast cancer but can also cause severe bone pain. A new study suggests a simple solution.

Todays Updates

From Pathology to Precision: The Story of Leukemia Therapy

From 19th century ‘white blood’ observations and pathological anatomy to the discovery of BCR-ABL and imatinib, leukemia care evolved from near-certain death to precise, life-extending therapies.

Delaying Pegfilgrastim May Curb Bone Pain in Breast Cancer

Pegfilgrastim helps prevent myelosuppression in women undergoing chemotherapy for breast cancer but can also cause severe bone pain. A new study suggests a simple solution.

Latest News

Excess abdominal fat — not overall body weight — may drive heart failure risk, with systemic inflammation being partially to blame.

Maintaining a healthy lifestyle was associated with a lower risk for major cardiometabolic diseases, regardless of antihypertensive medication use.

Pulse wave velocity, calculated from age and blood pressure changes, was associated with significant dementia risk in a post hoc SPRINT analysis.

A risk model predicts the risk for heart failure in patients with atherosclerotic cardiovascular disease and flags a notable proportion classified as low risk by other risk tools.

Eli Lilly and Company report top-line phase 3 clinical trial results for its investigational GLP-1, GIP, and glucagon agonist in people with type 2 diabetes.

The HHS Inspector General claims that some nursing homes are inappropriately diagnosing residents with schizophrenia and prescribing antipsychotics without proper oversight.

News All Time

Equation Choice May Affect CKD Staging in Primary Care

In the comparison of two equations for CKD stage classification in primary care, the CKD Epidemiology Collaboration equation places a higher proportion of patients in advanced stages.

Hormone Therapy Past Age 65 Tied to Cancer, Vascular Events

A large retrospective cohort study finds some cardiovascular benefits when HT is started earlier but generally supports guidelines discouraging use in older women.

Fast Metabolism May Signal Higher Diabetes Risk

Individuals with a higher estimated basal metabolic rate face a greater chance of developing diabetes and many of its complications, even after accounting for BMI, a study of 341,790 UK adults shows.

Preventing Sudden Death in Romano-Ward Syndrome

Romano-Ward syndrome, the most common congenital long QT disorder, often causes exertion- or stimulus-triggered syncope and sudden death; genetic testing and beta blockers guide prevention.

Why Is Extreme Heat a Mental Health Emergency?

As temperatures rise, so do sleepless nights, medication dangers, and social isolation, compounding vulnerability for those with mental illness.

Narrowing the Biological Age Gap Tied to Better Brain Health

Narrowing the gap between an individual’s biological and chronological age is linked to better brain health and a 23% reduced stroke risk, new research suggests.

Risk Score May Let Many With Chest Pain Skip Further Tests

The PROMISE minimal risk score identifies patients with recent-onset stable chest pain who can safely avoid extra testing and are less likely to have significant coronary disease or adverse events.

Cholesterol Guideline Emphasizes Earlier Treatment

A new cardiovascular calculator targeting individuals aged 30-79 years can help prevent atherosclerotic cardiovascular disease by estimating long-term risk for heart attack and stroke.

Frailty Index May Guide Blood Pressure Decision-Making

Frailty, rather than chronological age, more accurately distinguishes the ranges of systolic blood pressure that are linked to a lower risk for adverse cardiac events in patients with hypertension.

GLP-1 Drugs Show Benefits in Cushing Syndrome

GLP‑1 receptor agonists aid weight loss and improve glycaemic control and liver function in patients with Cushing syndrome and concurrent type 2 diabetes and/or obesity.

Antithrombotic Choice May Affect Bleed Risk in Endocarditis

The use of anticoagulation therapy at diagnosis of left-sided infective endocarditis may increase the risk for intracranial hemorrhage, especially when combined with antiplatelet therapy.

Anticoagulation Alone May Be Better for Patients With CAD

Oral anticoagulation alone is linked to lower risks for cardiovascular death and bleeding than adding an antiplatelet in stable coronary artery disease, with no higher risks for other poor outcomes.

Stents Placed Under Imaging Guidance Yield Better Outcomes

Stenting guided by intravascular imaging rather than angiography is linked to a lower risk for target vessel failure in patients with complex coronary artery lesions, a 5-year follow-up finds.

Med Op-Ed: TAVR Safety Signal, Limits of Famed Biobank, More

Opportunities to improve postmarketing surveillance of heart devices; how to validate findings based on UK Biobank data; and how to approach nonculprit lesions in STEMI.

Acid Blockers or PPI With Clopidogrel Tied to Stroke Risk

The use of potassium-competitive acid blockers or PPI with clopidogrel is associated with a higher risk for ischemic events after stroke than clopidogrel alone, a new study shows.

Clinics Closing the Cardiovascular-Mental Health Gap

Integrative clinics reflect a broader movement to close the long-standing gap between cardiovascular medicine and mental health care.

Recommended News For You

FDA Investigating Blood Cancer Risk With Gene Therapy Skysona

In patients with prostate cancer, second-generation antiandrogens may worsen fatigue, falls, and cognitive decline.

Housing aid linked to lower medical financial hardship among US renters with cancer

Classifying childhood brain cancers by immune response may improve diagnostics and treatments

Analysis of NRG trial in limited-stage small cell lung cancer suggests QOL benefit with twice- vs. once-daily radiation

Charles III, King of Kings, is Cancerous.

Maintenance Rituximab Improves Survival in Elderly MRD-Negative MCL Patients.

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