7 mars 2023

Published Date: 10 Mar 2023

Today's top stories include: Nine-year cap to complete MBBS, elective-based credits offered in NMC letter Students enrolled in...

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Blood and Heart Pressure Markers May Disagree in HFpEF

In patients with suspected heart failure with preserved ejection fraction, the levels of natriuretic peptides and resting filling pressure often disagree — and the risk for mortality depends on which one is high.

Donated Bodies and AI: Innovation or Ethical Dilemma?

Highly detailed anatomic data from donated bodies could support medical AI and 3D models, but differences in living anatomy and questions about data governance remain.

Lipedema: Liposuction Cuts Pain, but at What Cost?

New randomized evidence strengthens the case for liposuction in lipedema, but higher rates of complications and limited long-term data complicate treatment decisions.

Heart Size-Normalised Epicardial Fat May Rule Out CAD Risk

Normalising epicardial adipose tissue volume to total heart volume neutralises sex-based differences and provides a cutoff that may help rule out obstructive coronary artery disease.

Tirzepatide in Obesity: No AF Link but Arrhythmia Risk Noted

A meta-analysis finds no clear link between tirzepatide and odds of atrial fibrillation in adults with overweight or obesity, although it is linked to a modest increase in odds of overall arrhythmia.

ESC’s Joint Guidelines Bridge Cardiorenal Care

From mandatory dual-parameter screenings to aggressive blood pressure targets, the new ESC/ERA guidelines signal a major paradigm shift in cardiorenal care.

Todays Updates

Genetic Testing and Breast Cancer: Applying Guidelines and Clinical Evidence to the Identification and Management of Patients With Germline BRCA-Mutated Disease

Genetic Testing and Breast Cancer: Applying Guidelines and Clinical Evidence to the Identification and Management of Patients With Germline BRCA-Mutated Disease

Decrypting ADC Targets in PROC: Biomarker Expression, Testing, and Clinical Interpretation

Decrypting ADC Targets in PROC: Biomarker Expression, Testing, and Clinical Interpretation

Optimizing Use of Genetic Testing and Management of Care for Patients With Germline BRCA-Mutated Breast Cancer

Optimizing Use of Genetic Testing and Management of Care for Patients With Germline BRCA-Mutated Breast Cancer

FDA Expands Label of Oral HIV Drug to Newborns

Dolutegravir is already approved as combination therapy in adults and older children

Postpartum Psychosis: Who Is Most at Risk?

Disease has a continuum of severity, perinatal psychiatrist explains

U.S. Women Increasingly Not Screened for Cervical Cancer

Nearly one-third of women ages 21 to 29 had never undergone screening

These Women Face Higher Risk for Anal Sphincter Tears During Birth

Lifelong pelvic floor issues, such as incontinence, often ensue

Todays Updates

Genetic Testing and Breast Cancer: Applying Guidelines and Clinical Evidence to the Identification and Management of Patients With Germline BRCA-Mutated Disease

Genetic Testing and Breast Cancer: Applying Guidelines and Clinical Evidence to the Identification and Management of Patients With Germline BRCA-Mutated Disease

Decrypting ADC Targets in PROC: Biomarker Expression, Testing, and Clinical Interpretation

Decrypting ADC Targets in PROC: Biomarker Expression, Testing, and Clinical Interpretation

Optimizing Use of Genetic Testing and Management of Care for Patients With Germline BRCA-Mutated Breast Cancer

Optimizing Use of Genetic Testing and Management of Care for Patients With Germline BRCA-Mutated Breast Cancer

FDA Expands Label of Oral HIV Drug to Newborns

Dolutegravir is already approved as combination therapy in adults and older children

Postpartum Psychosis: Who Is Most at Risk?

Disease has a continuum of severity, perinatal psychiatrist explains

U.S. Women Increasingly Not Screened for Cervical Cancer

Nearly one-third of women ages 21 to 29 had never undergone screening

These Women Face Higher Risk for Anal Sphincter Tears During Birth

Lifelong pelvic floor issues, such as incontinence, often ensue

Latest News

In patients with suspected heart failure with preserved ejection fraction, the levels of natriuretic peptides and resting filling pressure often disagree — and the risk for mortality depends on which one is high.

Highly detailed anatomic data from donated bodies could support medical AI and 3D models, but differences in living anatomy and questions about data governance remain.

New randomized evidence strengthens the case for liposuction in lipedema, but higher rates of complications and limited long-term data complicate treatment decisions.

Normalising epicardial adipose tissue volume to total heart volume neutralises sex-based differences and provides a cutoff that may help rule out obstructive coronary artery disease.

A meta-analysis finds no clear link between tirzepatide and odds of atrial fibrillation in adults with overweight or obesity, although it is linked to a modest increase in odds of overall arrhythmia.

From mandatory dual-parameter screenings to aggressive blood pressure targets, the new ESC/ERA guidelines signal a major paradigm shift in cardiorenal care.

News All Time

Biomarkers May Help Predict PAP Benefit in Sleep Apnea

Two biomarkers, hypoxic burden and heart rate response, may help identify patients with obstructive sleep apnea who may derive greater cardiovascular benefits from long-term PAP therapy.

Childhood Reasoning Tied to Lower Later-Life Dementia Risk

Higher childhood inductive reasoning ability is associated with a lower risk for dementia decades later.

Aromatase Inhibitors: Old Drugs, New Combination Era

A 2025 multisociety update on aromatase inhibitor-associated bone loss lands just as ribociclib-AI combinations reshape early breast cancer care. Peyman Hadji, MD, explains what's changed.

Can Obesity Treatment With GLP-1 Drugs Last Forever?

Experts debate whether continued therapy or individualized decisions about dose reduction or stopping treatment is needed to preserve weight loss and cardiometabolic benefits.

Pulse Pressure Rise Begins Years Before Menopause

Analysis challenges menopause-related estrogen loss as the primary driver of midlife vascular aging.

Maternal Childhood Adversity Tied to Pregnancy Complications

Mothers with a history of significant childhood adversity are more likely to have pregnancy complications; however, birth outcomes appear unaffected.

Flutter vs Fibrillation: Which Is Tied to Lower Stroke Rate?

Atrial flutter alone is linked to a lower rate of ischaemic stroke events than atrial fibrillation alone, a Finnish nationwide study finds.

Sjögren Disease Linked to Increased Mortality Risk

Sjögren disease is associated with an increased risk for mortality, which is further elevated when the condition occurs alongside other connective tissue diseases.

Do Statins Still Matter in the GLP-1 Era?

Even as GLP-1 drugs transform obesity care and reduce cardiovascular risk, statins retain an essential role in lowering cholesterol and preventing cardiovascular risk events.

Direct Transfer to PCI Center Tied to Improved OHCA Survival

In patients with out-of-hospital cardiac arrest, direct transfer to a primary percutaneous coronary intervention center is associated with improved long-term survival.

Catheter Thrombolysis Cuts Risk in Pulmonary Embolism

In patients with intermediate- to high-risk pulmonary embolism, catheter-directed thrombolysis plus anticoagulation improves 7-day clinical outcomes when compared with anticoagulation alone.

Diabetes-Tailored DASH Diet Improves Glycemic Control in T2D

A DASH-style diet tailored for diabetes can lead to significant improvements in key glycemic biomarker levels among adults with type 2 diabetes (T2D).

The Dark Side of Full Patient Autonomy

Amid the backlash against paternalism and efforts to rebuild trust, an important ethical principle got caught in the fallout: the duty to act in the patient’s best interest.

CDK4/6 Inhibitors: One Class, Three Outcomes

Abemaciclib and ribociclib now show adjuvant survival benefit; palbociclib didn't. Laura Spring, MD, on picking the right agent per patient.

JAK Inhibitors Linked to Reduced Disease Activity in RA

JAK inhibitors are linked to reduced disease activity and improved patient-reported outcomes in patients with rheumatoid arthritis, regardless of diabetes, cardiometabolic burden, or age.

IL-6 May Predict HF Risk in Adults With Obesity and Diabetes

Higher interleukin 6 concentrations are linked to an increased risk for heart failure in adults with type 2 diabetes and overweight or obesity.

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Enthusiasm for Transplant-Free Strategies for Low-Risk Relapsed Hodgkin Lymphoma

Pharyngoesophageal junction cancer is not a good candidate for endoscopically assisted transoral surgery.

Scientists pioneer noninvasive 3D imaging to enhance skin cancer management

Delaying Pegfilgrastim May Curb Bone Pain in Breast Cancer

Key mechanism behind prostate cancer drug resistance reveals potential new treatment strategy

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