7 mars 2023

Published Date: 10 Mar 2023

Today's top stories include: Nine-year cap to complete MBBS, elective-based credits offered in NMC letter Students enrolled in...

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New Inclisiran Therapy Shows Reduction in LDL Cholesterol

New lipid-lowering therapy, administered subcutaneously just twice a year, offers significant and sustained reduction of LDL-C across a diverse group of patient populations.

FDA Expert Panel Backs Compounding of Six Peptides

If the agency follows the committee’s advice, it will issue a rule that would allow the compounds to be sold for any condition.

ACE Inhibitors vs ARBs: Long-Term Cancer Risk Varies

A 23-year analysis of hypertensive patients reveals differing cancer incidence patterns between two widely prescribed blood pressure medication classes, with variations across specific malignancies.

Infantile Hemangiomas: When Is a PHACE Workup Warranted?

Most congenital hemangiomas on the skin are managed with standard therapies, but an expert specified lesions that are at risk for systemic complications to provide guidance for rapid intervention.

The Endless (and Maddening) Quest to Make a Good Biosensor

Why is it so hard to create a reliable biosensor? The concurrent stories of several researchers — decades in the making — may at last be reaching their final acts.

Steroid Abuse Tied to Subtle Breathing Changes During Sleep

Androgen abuse in men is associated with modest changes in sleep-disordered breathing indices; however, sleep architecture remains largely preserved, and perceived sleep quality is unaffected.

Todays Updates

Trial Challenges Indefinite Maintenance for Multiple Myeloma

A randomized trial questions whether patients with standard-risk multiple myeloma need indefinite lenalidomide maintenance.

Blinatumomab May Improve Survival in High-Risk Adult B-ALL

A phase 2 trial evaluates the benefit of adding blinatumomab to consolidation therapy in adults with high-risk Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia.

Todays Updates

Trial Challenges Indefinite Maintenance for Multiple Myeloma

A randomized trial questions whether patients with standard-risk multiple myeloma need indefinite lenalidomide maintenance.

Blinatumomab May Improve Survival in High-Risk Adult B-ALL

A phase 2 trial evaluates the benefit of adding blinatumomab to consolidation therapy in adults with high-risk Philadelphia chromosome-negative B-cell acute lymphoblastic leukemia.

Latest News

New lipid-lowering therapy, administered subcutaneously just twice a year, offers significant and sustained reduction of LDL-C across a diverse group of patient populations.

If the agency follows the committee’s advice, it will issue a rule that would allow the compounds to be sold for any condition.

A 23-year analysis of hypertensive patients reveals differing cancer incidence patterns between two widely prescribed blood pressure medication classes, with variations across specific malignancies.

Most congenital hemangiomas on the skin are managed with standard therapies, but an expert specified lesions that are at risk for systemic complications to provide guidance for rapid intervention.

Why is it so hard to create a reliable biosensor? The concurrent stories of several researchers — decades in the making — may at last be reaching their final acts.

Androgen abuse in men is associated with modest changes in sleep-disordered breathing indices; however, sleep architecture remains largely preserved, and perceived sleep quality is unaffected.

News All Time

Climate Hazards Could Hurt World Cup Performance

Extreme heat, humidity, altitude, and travel-related disruptions may challenge 2026 World Cup players’ endurance, recovery, and overall performance.

The Muscle Conversation That Will Motivate Your Patients

What patients ‘think’ is important about muscle isn’t usually what will benefit them most — especially if they’re hesitant to strength train.

HF Polypill May Improve Drug Adherence, a Pilot Trial Finds

Customizable polypill for patients with heart failure with reduced ejection fraction may improve adherence and lower pill burden, and its use appears feasible and acceptable.

Stroke Survivors Aged 50 or Older See Life Expectancy Gains

Life expectancy at age 50 years has increased in US individuals with a history of stroke.

Statins May Slow Cognitive Decline in Women With AD

In an observational study, statin use was associated with slower cognitive decline in women with Alzheimer’s disease and elevated low-density lipoprotein cholesterol.

Should We Be Concerned About Muscle Loss With GLP-1s?

Two experts debated this question at the American Diabetes Association 2026 Scientific Sessions.

Ramipril Supply Limit Extended to October

The one-month ramipril supply limit, in place since April, now runs to 30 October as UK pharmacists renew calls to allow substitutions.

New Guidelines Expand Statin Eligibility to 50% of US Adults

New US dyslipidemia guidelines make 87.5 million adults eligible for primary prevention statin therapy to reduce the risk for stroke and other cardiovascular diseases.

Oral PCSK9 Inhibitor Welcomed for Potential in Primary Care

The recent approval of enlicitide was seen as a boon for some clinical scenarios, although real-world impact remains to be seen.

Machine Learning May Simplify Estimation of LDL Cholesterol

A machine learning-based equation may estimate low-density lipoprotein cholesterol as accurately as the widely validated Martin-Hopkins method while offering easier implementation for clinical care.

What Will It Take to Make Fluoroscopy Labs Safer?

Six major medical societies released a joint statement calling for mandatory implementation of enhanced radiation protection devices in fluoroscopy labs.

Obesity Treatment Advances, but Access Gaps Persist

Obesity care is evolving fast, but experts at ICO 2026 warned that access to treatment, prevention strategies, and policy follow-through remain deeply uneven.

Finerenone Lowers Blood Pressure in HFmrEF or HFpEF

Finerenone produced sustained reductions in systolic BP and consistently reduced cardiovascular death and heart failure events across a broad BP spectrum in patients with HFmrEF or HFpEF.

OAC After AF Ablation Benefits High-Risk Patients

In patients with elevated stroke risk, continuing oral anticoagulation after atrial fibrillation ablation was associated with lower thromboembolic events, though bleeding risk remained elevated across all groups.

Lipid-Lowering Med Advances to Alzheimer’s Prevention Trial

The lipid-lowering drug obicetrapib produces the greatest reductions in the Alzheimer’s biomarker p-tau217 among APOE4 carriers, providing the rationale for a planned Alzheimer’s prevention trial.

NPs Safely Manage MRI in Patients With Cardiac Devices

Nurse practitioner-led cardiac implantable electronic device management enables MRI without clinically significant lead parameter changes, arrhythmias, or patient-reported symptoms, a study reports.

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‘Bar Code’ Biopsy From RNA Could Guide Precision Oncology

BMI is linked to heart damage from chemotherapy in breast cancer patients.

Momelotinib, a JAK inhibitor, has FDA approval to treat adult myelofibrosis in anemic patients.

FDA Leaders Explain Their Choice Regarding Cancer Risk Warning in CAR-T Investigation.

Cancer Diagnoses Still Lagging; Cancer and Family Health; New Type of Lung Cancer

Blinatumomab Plus Chemotherapy New Standard for Children With B-Cell ALL

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