7 mars 2023

Published Date: 10 Mar 2023

Today's top stories include: Nine-year cap to complete MBBS, elective-based credits offered in NMC letter Students enrolled in...

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Phase 3 HCM Drug Offers Promising Results in Exercise Tests

Treatment with aficamten may improve multiple measures of exercise in patients with obstructive hypertrophic cardiomyopathy, a study finds.

GLP-1s Tied to Higher Risk for Dizziness, Fainting for Some

Hypotension-related events increased after starting GLP-1s in patients taking multiple antihypertensive medications.

Early Pregnancy Thyroid Issues Signal Later Hypothyroidism

Thyroid abnormalities in early pregnancy are associated with an increased risk of developing hypothyroidism later in life.

Will Genomics Move From Innovation to Routine Care?

Pharmacogenomics and polygenic risk scores could replace trial-and-error prescribing — but workflow, trust, and equity stand in the way.

GLP-1 Therapy: Can a Myostatin Antibody Preserve Muscle?

A phase 2 trial suggests myostatin inhibition may reduce lean body mass loss during tirzepatide treatment while maintaining overall weight reduction.

How Extreme Heat Threatens Athlete Safety

High temperatures, humidity, and prolonged exertion can overwhelm the body’s cooling systems. Here’s what clinicians should know about heat risk in sport.

Todays Updates

Timely ‘Nudges’ Help Spur Talks on Patient Care Goals

Simple well-timed prompts to clinicians and patients with advanced cancer can increase conversations around care goals, but clear documentation remains a challenge.

Todays Updates

Timely ‘Nudges’ Help Spur Talks on Patient Care Goals

Simple well-timed prompts to clinicians and patients with advanced cancer can increase conversations around care goals, but clear documentation remains a challenge.

Latest News

Treatment with aficamten may improve multiple measures of exercise in patients with obstructive hypertrophic cardiomyopathy, a study finds.

Hypotension-related events increased after starting GLP-1s in patients taking multiple antihypertensive medications.

Thyroid abnormalities in early pregnancy are associated with an increased risk of developing hypothyroidism later in life.

Pharmacogenomics and polygenic risk scores could replace trial-and-error prescribing — but workflow, trust, and equity stand in the way.

A phase 2 trial suggests myostatin inhibition may reduce lean body mass loss during tirzepatide treatment while maintaining overall weight reduction.

High temperatures, humidity, and prolonged exertion can overwhelm the body’s cooling systems. Here’s what clinicians should know about heat risk in sport.

News All Time

Med Op-Ed: Dying of Old Age, Gambling Screening, and More

A leading cause of death in Japan does not follow global medical conventions; why primary care clinicians should screen for gambling disorder; and a trial refutes vitamin C as a treatment for severe burns.

What Anxiety and Depression Signal in Atrial Fibrillation

Anxiety and depression are linked to a higher risk for death and major adverse cardiovascular events, with a greater risk at higher symptom severity, prompting closer attention in routine care.

The Evolving Landscape of Sickle Cell Disease Treatment

Gene therapy and small molecules are opening the door to new curative approaches, but access continues to be a barrier for most patients.

Which Factors Affect Heart Health in Indigenous Canadians?

Unconventional research highlights the need for models of cardiac care that combine Indigenous and Western knowledge systems.

Alcohol-Induced Deaths: Australian Experts Call for Support

Deaths from alcohol show no sign of declining, and some experts are calling for stronger regulation of alcohol advertising and more specialist services to meet demand.

Patients on GLP-1s: Drugs Aren’t a ‘Magic Bullet’

GLP-1s aren’t a miracle weight-loss solution but a tool that facilitates behavior change and that comes with some significant downsides, the drugs’ users tell researchers.

Can AI Match Physicians’ Judgment, Not Just Diagnosis?

Studies show that AI increasingly matches or exceeds physicians on select diagnostic tasks, yet experts stress that clinical judgment remains essential.

Low Lp(a) Not Linked to Most Safety Risks in ASCVD Patients

Low levels of lipoprotein(a) are not linked to most safety risks, except for a modest increase in the risk for diabetes, a study finds.

Bad Bunny Joins the CPR Playlist

From Bad Bunny to Celia Cruz, music is being used to teach CPR rhythm, and experts say the right beat may help rescuers stay on pace.

App May Help Reduce Same-Day Cardioversion Cancellations

Smartphone-based monitoring of heart rhythm before cardioversion may help reduce same-day cancellations and detect spontaneous changes in heart rhythm in patients with atrial fibrillation or flutter.

JAK Inhibitors Effective in RA, Safer With Risk-Based Use

JAK inhibitors show effectiveness and persistence in routine care of adults with rheumatoid arthritis, and cautious patient selection under new recommendations is linked to safer outcomes.

Does Lenvatinib Plus Nivolumab Extend Survival in HCC?

The combination of lenvatinib and nivolumab may enhance survival outcomes in patients with unresectable advanced hepatocellular carcinoma, a single-arm trial reports.

Migraine With Aura Tied to Higher Stroke Risk

Migraine with aura is associated with an increased risk for ischemic stroke in middle-aged and older adults, particularly men younger than 72 years, a new study shows.

Is Modern Medicine Losing the Art of Listening?

Patients place high value on listening, trust, and clear communication, which are factors that shape adherence, satisfaction, and the overall experience of care.

Semaglutide Tablet Wins UK Approval for Weight Loss

The MHRA has approved the UK's first oral semaglutide tablet for obesity, with NHS availability pending a NICE evaluation.

New Deep Learning Model Parcellates Brain Using Only dMRI

A novel hierarchical deep learning framework enables direct Desikan-Killiany brain parcellation using only diffusion MRI-derived data, removing the need for structural scans.

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The diamonds that could find cancer

For the creation of cutting-edge targeted radionuclide therapies in oncology, Bayer and Bicycle Therapeutics work together.

Acupuncture may alleviate nocturia in men treated for prostate cancer

Chronic stress and obesity work together to accelerate pancreatic cancer development and growth, study finds

Unlocking the secrets of the fibrotic fortress that surrounds and protects pancreatic cancer

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