7 mars 2023

Published Date: 10 Mar 2023

Today's top stories include: Nine-year cap to complete MBBS, elective-based credits offered in NMC letter Students enrolled in...

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Therapy-Intense Training Linked to Improved Sleep Outcomes

Combining high-intensity circuit training with a sleep health program is tied to better sleep outcomes in sedentary women than either intervention alone, a new study shows.

AHA, ACC Issue Comprehensive Guidelines on Acute PE

The first multisociety guidelines on the diagnosis and management of acute pulmonary embolism feature a new classification system.

Paclitaxel Devices Should Not Be Routine for Claudication

An MHRA advisory group says paclitaxel-coated balloons and stents should not be used routinely for intermittent claudication over mortality concerns.

Ramipril Batch Recalled After Amlodipine Found in Packs

The MHRA has recalled a batch of ramipril after a packaging error meant some cartons contained amlodipine tablets instead of the labelled medicine.

The Many Cardiovascular Benefits of GLP-1 Drugs

Diabetes and obesity drugs also lead to large reductions in adverse cardiovascular events, and the benefits aren’t just down to weight loss.

Aspirin May Reduce Aortic Stenosis in People With High Lp(a)

New evidence shows regular aspirin use is associated with a lower incidence of aortic valve calcification and aortic stenosis, specifically in people with high lipoprotein(a).

Todays Updates

Have the Harms of Lung Cancer Screening Been Exaggerated?

Three medical societies claim recent studies have overestimated the potential harms from lung cancer screening and may be deterring patients. Not everyone agrees.

Pretreatment Liver Tests Often Overlooked in CDK4/6 Therapy

Despite FDA package insert recommendations, most patients with breast cancer who are prescribed CDK4/6 inhibitors do not receive liver function tests before starting treatment.

Alternative Medicine for Breast Cancer: Study Raises Concern

Patients who receive both standard medical treatment and complementary and alternative therapies have higher mortality — possibly due to reduced use of endocrine therapy and radiation.

Todays Updates

Have the Harms of Lung Cancer Screening Been Exaggerated?

Three medical societies claim recent studies have overestimated the potential harms from lung cancer screening and may be deterring patients. Not everyone agrees.

Pretreatment Liver Tests Often Overlooked in CDK4/6 Therapy

Despite FDA package insert recommendations, most patients with breast cancer who are prescribed CDK4/6 inhibitors do not receive liver function tests before starting treatment.

Alternative Medicine for Breast Cancer: Study Raises Concern

Patients who receive both standard medical treatment and complementary and alternative therapies have higher mortality — possibly due to reduced use of endocrine therapy and radiation.

Latest News

Combining high-intensity circuit training with a sleep health program is tied to better sleep outcomes in sedentary women than either intervention alone, a new study shows.

The first multisociety guidelines on the diagnosis and management of acute pulmonary embolism feature a new classification system.

An MHRA advisory group says paclitaxel-coated balloons and stents should not be used routinely for intermittent claudication over mortality concerns.

The MHRA has recalled a batch of ramipril after a packaging error meant some cartons contained amlodipine tablets instead of the labelled medicine.

Diabetes and obesity drugs also lead to large reductions in adverse cardiovascular events, and the benefits aren’t just down to weight loss.

New evidence shows regular aspirin use is associated with a lower incidence of aortic valve calcification and aortic stenosis, specifically in people with high lipoprotein(a).

News All Time

Smartwatch Hypertension Alerts Shouldn’t Replace Screening

Receiving an alert increased the probability of undiagnosed hypertension, but absence of an alert did not reliably rule it out and should not replace cuff-based screening.

Can Drug-Eluting Balloons Challenge Stents in STEMI?

Proponents argue drug-eluting balloons avoid permanent implants and may shorten dual antiplatelet therapy, whereas critics warn of vessel dissection and the need for bailout stenting.

Patients and GPs Unite Over NHS ‘Maze’

GPs are spending up to a third of their time on paperwork, as patients and doctors warn that NHS bureaucracy is undermining care.

Gear Up Now for Daylight Savings Time: Five Steps

Take these steps to get you and your patients ready to transition to your new local time with minimal adverse health effects.

Low-Risk TAVR Matches SAVR at 6 Years; Reinterventions Rise

Six-year follow-up from a trial comparing surgery with TAVR in low-risk patients showed no difference in major events, but the reintervention was higher in the TAVR arm.

Are Visual Deficits After Stroke Being Missed?

The European Stroke Organization calls for systematic screening within days of stroke to detect visual deficits that affect up to three quarters of survivors.

Is Stroke Underrecognized After Snakebite?

Experts call for urgent neuroimaging access, structured referral pathways, and standardized protocols to reduce disability and deaths following snake envenoming.

Off-Pump Beats On-Pump CABG in Short-Term Outcomes

Perioperative morbidity and mortality were reduced with off-pump vs on-pump coronary artery bypass grafting, though survival evened out over the long term.

Universities Unite to Tackle CVD Inequality

A £50 million research partnership will target heart health gaps affecting deprived communities, ethnic minority groups, and women in the UK.

Heart Symptoms Common in Seniors Without Cardiac Disease

Older adults with no diagnosis of cardiac disease often experience heart-related symptoms such as fatigue, exertional shortness of breath, and tachycardia, which are linked to poor quality of life.

CKM Syndrome Recognition and Collaboration Gaining Traction

While first-ever guidelines are in the works, experts across specialties share their take on the current state of preventing, diagnosing, and managing CKM syndrome.

CT-Quantified Plaque Volume May Predict CAD

Plaque burden predicts major adverse cardiac events, independent of other risk factors.

EMA Rejects Drugs for Rett Syndrome, Schizophrenia

Daybue was turned down for Rett syndrome, and Iloperidone for schizophrenia and bipolar I, with safety and benefit-risk concerns cited in both cases.

Resuscitation’s Ethical Dilemma: Rethink Epinephrine Use

Epinephrine improves ROSC in cardiac arrest but does not increase favorable neurologic recovery, raising ethical and guideline questions for clinicians.

Bariatric Surgery Beats GLP-1s for Heart Protection in T2D

A meta-analysis of 11 studies involving over 19,000 patients with T2D and obesity shows that bariatric surgery provides greater cardiovascular protection and mortality reduction than GLP-1 drugs.

Tenecteplase May Help Stroke Recovery Past 4.5-Hour Window

Some patients with a common type of stroke benefit from a clot-busting drug given between 4.5 and 24 hours after symptoms emerged, according to a new study.

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No PFS Benefit With Immune Checkpoint Inhibitor Rechallenge in Renal Cell Carcinoma

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Standardized criteria for amino acid PET imaging could improve diagnosis and treatment of brain metastases

Immunotherapy after surgery is good for patients with advanced cancer

Unlocking the potential of targeted therapies for multiple myeloma

Navigating breast cancer diagnosis, treatment, and survivorship in Ethiopia

Disparities in use of MRI to detect prostate cancer: Race and location may influence testing

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