Even if the pain is mild or hard on the brain

Published Date: 08 Mar 2023

A new study shows structural and functional changes in the brain associated with anxiety and depression after mild COVID-19 infection.

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Esophagitis Dissecans Superficialis in Woman With Dysphagia

A woman presents with progressive dysphagia and vomiting; endoscopy reveals extensive esophageal mucosal sloughing consistent with esophagitis dissecans superficialis.

Laughter Really Is The Best Medicine

The data on laughter are more serious than you’d expect. Dr Neil Skolnik breaks down the physiological benefits of humor.

AI in Medicine Reduces Burden, Not Judgment

AI in medicine isn’t about replacing clinical reasoning. It’s about freeing up physicians to do more of what only they can do.

Gaps in Access to Maternity Care Tied to Labor Induction

Maternal residence in rural, lower-access counties is associated with an increased risk for labor induction at full term.

New CRP Cutoff Can Flag High-Risk Ulcerative Colitis Cases

Lowering the CRP threshold helps identify hospitalized patients with ulcerative colitis at a risk for colectomy who would have been missed by the traditional criteria.

PPI Linked to Lower Gastric Cancer Mortality Risk

In contrast to prior research showing PPI may mask signs of gastric cancer and delay diagnosis, new research shows diagnosis was in fact earlier and mortality, lower.

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Osimertinib's OS Benefit in Resected NSCLC Persists 8 Years

Even years after treatment ends, adjuvant osimertinib brings an overall survival benefit to patients with resected EGFR-mutated lung cancer.

Pelvic RT Tied to Longer Survival in Cervical Cancer

In patients with newly diagnosed stage IVB cervical cancer, adding definitive-dose pelvic radiotherapy to chemotherapy was associated with longer survival compared with chemotherapy alone.

New Data Put ADCs on the Map in Relapsed SCLC

Two B7-H3-directed antibody-drug conjugates substantially improve survival over topotecan among patients with relapsed small cell lung cancer — pointing to a potential new treatment class.

Real-World Liso-Cel Results in MCL Consistent With Trials

Two analyses of liso-cel CAR T-cell therapy in relapsed or refractory mantle cell lymphoma show response rates in the real-world setting similar to those seen in clinical trial populations.

Antibiotic Use in Hospice Linked to Higher Mortality Risk

Antibiotic use in patients under hospice care is associated with an increased risk for mortality; for infectious hospice-qualifying conditions, antibiotic use is linked to extended survival.

Todays Updates

Osimertinib's OS Benefit in Resected NSCLC Persists 8 Years

Even years after treatment ends, adjuvant osimertinib brings an overall survival benefit to patients with resected EGFR-mutated lung cancer.

Pelvic RT Tied to Longer Survival in Cervical Cancer

In patients with newly diagnosed stage IVB cervical cancer, adding definitive-dose pelvic radiotherapy to chemotherapy was associated with longer survival compared with chemotherapy alone.

New Data Put ADCs on the Map in Relapsed SCLC

Two B7-H3-directed antibody-drug conjugates substantially improve survival over topotecan among patients with relapsed small cell lung cancer — pointing to a potential new treatment class.

Real-World Liso-Cel Results in MCL Consistent With Trials

Two analyses of liso-cel CAR T-cell therapy in relapsed or refractory mantle cell lymphoma show response rates in the real-world setting similar to those seen in clinical trial populations.

Antibiotic Use in Hospice Linked to Higher Mortality Risk

Antibiotic use in patients under hospice care is associated with an increased risk for mortality; for infectious hospice-qualifying conditions, antibiotic use is linked to extended survival.

Latest News

A woman presents with progressive dysphagia and vomiting; endoscopy reveals extensive esophageal mucosal sloughing consistent with esophagitis dissecans superficialis.

The data on laughter are more serious than you’d expect. Dr Neil Skolnik breaks down the physiological benefits of humor.

AI in medicine isn’t about replacing clinical reasoning. It’s about freeing up physicians to do more of what only they can do.

Maternal residence in rural, lower-access counties is associated with an increased risk for labor induction at full term.

Lowering the CRP threshold helps identify hospitalized patients with ulcerative colitis at a risk for colectomy who would have been missed by the traditional criteria.

In contrast to prior research showing PPI may mask signs of gastric cancer and delay diagnosis, new research shows diagnosis was in fact earlier and mortality, lower.

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Case of Severe Delayed ICI-Mediated Colitis and Pneumonitis

Immune checkpoint inhibitors have revolutionized the treatment of advanced malignancies by restoring T-cell mediated antitumor immunity.

Teleoncology Model to Improve Access for Vets With GU Cancer

This study evaluated the impact of a VA teleoncology hub-and-spoke model on care access and travel burden for veterans with genitourinary malignancies.

Racial Disparities in Nonmelanoma Skin Cancer Mortality

This study evaluated racial differences in age-adjusted mortality rates for nonmelanoma skin cancer mortality trends in the US from 1999-2023.

Swapping Sedentary Time for Activity May Curb Depression

Reallocating 15 minutes of daily sedentary behaviour with moderate-to-vigorous physical activity is associated with lower depressive symptoms among university students.

Family History May Up CRC Risk in IBD, in General Population

Patients with IBD who have multiple first-degree relatives with colorectal cancer face an elevated risk for colorectal cancer, as do individuals without IBD who have a similar family history.

Q&A: Is Perimenopause a Medical Condition?

JoAnn Manson, MD, MPH, DrPH, discusses the management of perimenopause and its ascendance in the minds of women and the media.

Suicidal Ideation Linked to Adolescent Suicide Attempt Risk

Adolescents with suicidal ideation face elevated odds of suicide attempts regardless of their overall mental health status, an analysis of a survey shows.

Could Tavapadon Change Parkinson's Care?

If approved by the FDA, tavapadon would be the first new dopamine agonist for Parkinson's disease in decades. What does the research show about efficacy and safety?

White House Says It Will Send $500 Obamacare Refunds to Nearly a Million Americans

The White House said on Thursday it will send $500 to nearly one million Americans in 30 states who are enrolled in Obamacare health insurance plans, payments it described...

Disparities in Urban and Rural Mortality from Non-Melanoma Skin Cancers

This study assessed differences in age-adjusted mortality rates in nonmelanoma skin cancer in U.S. urban and rural populations.

Improving Resident Attitudes Toward Patients with SCA

This study evaluated whether a CAB-designed educational intervention could improve resident physician attitudes toward patients with SCA.

Does This New Clue Explain the Smoking-Parkinson’s Mystery?

Carbon monoxide may help explain the long-observed but perplexing association between smoking and a lower risk for Parkinson’s disease.

Cancer Screening Lower for Adults With Disabilities

A new study finds millions of adults with disabilities are missing critical cancer screenings, but those with disabilities have higher rates of at-home stool testing for colorectal cancer.

Early Remdesivir May Protect Kidney Grafts After COVID

Early antiviral intervention is associated with lower risks for graft loss and cardiovascular events in kidney transplant recipients with COVID.

The Future of Oncology Clinical Pathways in VHA

VA oncology Clinical Pathways logged 26,613 entries for 11,835 patients in FY25, standardizing care and paving the way to Oracle Health EHR.

Normal, but Not Optimal: Rethinking Perimenopause

In this roundtable, Drs Rachel Rubin, Makeba Williams, and Anna Cabeca discuss the changing landscape of perimenopause care — and why every clinician should join the conversation.

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Trump Issues Gag Order for CDC, FDA; Stalled Hearing for RFK Jr.; Sex After Cancer

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