Even if the pain is mild or hard on the brain

Published Date: 08 Mar 2023

A new study shows structural and functional changes in the brain associated with anxiety and depression after mild COVID-19 infection.

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May 29 2026 This Week in Cardiology

A life-long treatment for high LDL, a VESALIUS subanalysis, tirzepatide beats semaglutide again, arrhythmia burden in cardiac amyloidosis, and a lipid guideline rebuttal are the topics John Mandrola, MD, discusses in this week’s podcast.

Man Suffers Vagal Bradycardia After Abdominal Trauma

After a baseball collision, a 51-year-old man presents with bradycardia that progresses to shock; imaging finds a large mesenteric hematoma that requires atropine and urgent surgery.

Former FDA Commissioner on Fighting Medical Misinformation

Bob Harringson and former FDA commissioner Rob Califf discuss medical misinformation, its impact on public and individual health, and how to fight against it.

Rising CRC Rates a ‘Wake Up Call’ for Gastroenterologists

With increasing rates of colorectal cancer being seen in younger patients, Dr Alicia Muratore explains why gastroenterologists should be diligent when screening for and addressing risk factors.

Novel Psychedelic Shows Rapid, Lasting Benefit in PPD

Luvesilocin, a novel psychedelic compound, provides rapid and durable symptom improvement in women with postpartum depression, phase 2 trial results suggest.

Early-Life Stress Raises Gastrointestinal Disease Risk

A study finds adverse early events are linked to gut-brain disruptions in mice and humans.

Todays Updates

A Century of Schizophrenia: One Disorder or Many?

Researchers increasingly suggest that biological diversity within schizophrenia may limit efforts to identify a single defining biomarker.

Snus Linked to Gingival Damage, Raising Safety Questions

Research shows that snus and newer oral nicotine pouches are associated with localized soft tissue changes, prompting greater attention to their oral health effects.

Todays Updates

A Century of Schizophrenia: One Disorder or Many?

Researchers increasingly suggest that biological diversity within schizophrenia may limit efforts to identify a single defining biomarker.

Snus Linked to Gingival Damage, Raising Safety Questions

Research shows that snus and newer oral nicotine pouches are associated with localized soft tissue changes, prompting greater attention to their oral health effects.

Latest News

A life-long treatment for high LDL, a VESALIUS subanalysis, tirzepatide beats semaglutide again, arrhythmia burden in cardiac amyloidosis, and a lipid guideline rebuttal are the topics John Mandrola, MD, discusses in this week’s podcast.

After a baseball collision, a 51-year-old man presents with bradycardia that progresses to shock; imaging finds a large mesenteric hematoma that requires atropine and urgent surgery.

Bob Harringson and former FDA commissioner Rob Califf discuss medical misinformation, its impact on public and individual health, and how to fight against it.

With increasing rates of colorectal cancer being seen in younger patients, Dr Alicia Muratore explains why gastroenterologists should be diligent when screening for and addressing risk factors.

Luvesilocin, a novel psychedelic compound, provides rapid and durable symptom improvement in women with postpartum depression, phase 2 trial results suggest.

A study finds adverse early events are linked to gut-brain disruptions in mice and humans.

News All Time

CAR-T Therapy Shows Promise in CNS and Extramedullary B-ALL

A retrospective study evaluates the effectiveness of CD19 CAR T-cell therapy in relapsed/refractory B-cell acute lymphoblastic leukemia with extramedullary or CNS disease.

Reassuring Data for Two High-Efficacy MS Meds in Pregnancy

Two longitudinal studies showed no adverse safety signals associated with prenatal exposure to two high-efficacy drugs for MS.

In Defense of the 2026 Dyslipidemia Guideline

Members of the writing committee for the 2026 ACC/AHA/Multisociety dyslipidemia guidelines respond to a critical column by John Mandrola, MD.

Could AI Bias Make Health Inequalities Worse?

AI bias isn't just a tech problem — it's a potential patient safety issue that every clinician needs to understand.

Machine Learning Predicts Recurrence of Barrett's Esophagus

A machine learning model predicted the risk for recurrence of Barrett's esophagus and related neoplasia in certain patients.

Social Contact, Not Kinship, May Shape Gut Flora

Close social interactions during cooperative breeding, rather than genetic relatedness, may drive sharing of anaerobic gut bacteria, according to an animal study.

Yoga Eases Insomnia, Fatigue, Anxiety in Cancer Survivors

In a phase 3 trial, cancer survivors who practiced gentle yoga reported better sleep and improvements in fatigue, anxiety, and mood disturbance.

Surgery Linked to Slight Cognitive Decline in Older Adults

About 60% of older adults face slight cognitive decline over a period of 6 years after major surgery, a study finds.

‘Something Died in Me’: Why Dedicated Doctors Quit Medicine

Doctors are leaving medicine in growing numbers, and burnout is only part of the story.

Biologics Continue to Revolutionize Psoriasis Care

Biologic therapies have a huge impact on psoriasis treatment, helping patients achieve clearer or clear skin, although issues about cost, access, and how long maintenance therapy is warranted remain.

How This Rheumatologist Missed Her Own Rheumatoid Arthritis

She’d diagnosed rheumatoid arthritis dozens of times but dismissed her own symptoms and fought her eventual diagnosis. Today she’s the best doctor she can be.

First Guidance on Deprescribing Stimulants in Adult ADHD

The first-ever deprescribing consensus guidance for adult ADHD stimulants has been published alongside the largest dose-effect analysis of the drugs to date.

For Farmers, Mental Health Care That Fits

Two recently launched initiatives endorse ‘farm-informed therapy’ to support mental health in the prairie provinces.

Is Venetoclax Retreatment Effective in Relapsed CLL?

Researchers review available clinical evidence for retreatment with venetoclax, alone or in combination, in patients with relapsed chronic lymphocytic leukemia.

Prenatal Vitamin D Linked to Modest Gains in Child Memory

High-dose vitamin D3 supplementation during pregnancy may improve memory in children.

Genetic Testing for Kidney Disease Often Not Discussed

A survey found that clinicians are not discussing genetic testing with 80% of patients with kidney disease who meet established clinical criteria.

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