Even if the pain is mild or hard on the brain

Published Date: 08 Mar 2023

A new study shows structural and functional changes in the brain associated with anxiety and depression after mild COVID-19 infection.

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Latest News

Combination Therapy Boosts Remission in Ulcerative Colitis

In patients with ulcerative colitis, endoscopic remission rates are more than twofold higher after an induction with upadacitinib plus vedolizumab vs vedolizumab monotherapy.

The Force Is With You: How Trust Shapes Cancer Care

Oncologists spend years learning to trust their own judgment, an ability that marries intuition with reasoning. What happens to that hard-won skill when AI starts doing the pattern-matching for them?

Youth Who Get Smartphones at 13 Likely to Face Health Issues

Smartphone acquisition at 13 years of age is linked to insufficient sleep at 14 years of age; a greater duration of use is associated with higher risks for depression, obesity, and insufficient sleep.

NHS Trusts Unable to Account for £400m of Training Cash

A BMJ investigation finds nearly £400 million of NHS funding for medical student placements is unaccounted for — and mandatory reporting has now been dropped.

Diagnosing Alpha-Gal Syndrome in Children

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

High Blood Pressure? Consider the Aldosterone Connection

Less than 1% of patients with primary aldosteronism are diagnosed. The Curbsiders are here to help change that with practical screening and treatment tips.

Todays Updates

Roosevelt’s Public Image and Overlooked Illness

A 2023 review reexamines Yalta through a medical lens, showing how Roosevelt’s deteriorating cardiovascular status may have been underestimated.

Gaps Exist in Cardiometabolic Risk Factor Treatment for CKM

Management of cardiometabolic risk factors for cardiovascular-kidney-metabolic syndrome falls short, particularly for younger adults, who have the lowest treatment rates.

Statin Initiation Tied to Lower Frailty Risk in Older Adults

Starting statins is associated with a reduced risk for frailty in older adults, including those with prefrailty at baseline.

FDA Okays Drug to Curb Pancreatitis in Hypertriglyceridemia

The expanded indication makes olezarsen the first therapy approved to reduce the acute pancreatitis risk in adults with severe hypertriglyceridemia.

Patient Communication Is Your Best Resource in Rheumatology

Investing time in upfront patient communication improves self-management, builds trust, and reduces the need for long-term clinic visits.

Extreme Heat: Are Health Risks Being Underestimated?

Extreme heat affects the heart, lungs, kidneys, and brain while increasing hospital admissions, preterm birth, and pressure on the healthcare system.

Drug to Prevent Organ Rejection After Kidney Transplant Tops Standard Treatment in Trial

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays)

Todays Updates

Roosevelt’s Public Image and Overlooked Illness

A 2023 review reexamines Yalta through a medical lens, showing how Roosevelt’s deteriorating cardiovascular status may have been underestimated.

Gaps Exist in Cardiometabolic Risk Factor Treatment for CKM

Management of cardiometabolic risk factors for cardiovascular-kidney-metabolic syndrome falls short, particularly for younger adults, who have the lowest treatment rates.

Statin Initiation Tied to Lower Frailty Risk in Older Adults

Starting statins is associated with a reduced risk for frailty in older adults, including those with prefrailty at baseline.

FDA Okays Drug to Curb Pancreatitis in Hypertriglyceridemia

The expanded indication makes olezarsen the first therapy approved to reduce the acute pancreatitis risk in adults with severe hypertriglyceridemia.

Patient Communication Is Your Best Resource in Rheumatology

Investing time in upfront patient communication improves self-management, builds trust, and reduces the need for long-term clinic visits.

Extreme Heat: Are Health Risks Being Underestimated?

Extreme heat affects the heart, lungs, kidneys, and brain while increasing hospital admissions, preterm birth, and pressure on the healthcare system.

Drug to Prevent Organ Rejection After Kidney Transplant Tops Standard Treatment in Trial

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays)

Latest News

In patients with ulcerative colitis, endoscopic remission rates are more than twofold higher after an induction with upadacitinib plus vedolizumab vs vedolizumab monotherapy.

Oncologists spend years learning to trust their own judgment, an ability that marries intuition with reasoning. What happens to that hard-won skill when AI starts doing the pattern-matching for them?

Smartphone acquisition at 13 years of age is linked to insufficient sleep at 14 years of age; a greater duration of use is associated with higher risks for depression, obesity, and insufficient sleep.

A BMJ investigation finds nearly £400 million of NHS funding for medical student placements is unaccounted for — and mandatory reporting has now been dropped.

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

Less than 1% of patients with primary aldosteronism are diagnosed. The Curbsiders are here to help change that with practical screening and treatment tips.

News All Time

Novel Narcolepsy Drug Delivers Benefits Beyond Wakefulness

The oral orexin receptor 2 agonist improved cognitive performance, daily functioning, and work productivity in addition to wakefulness and cataplexy control, new phase 3 data show.

US Doctors Seek Better Working Conditions in Canada

US doctors are emigrating to Ontario, British Columbia, and Nova Scotia in response to increasing healthcare bureaucracy and political tensions at home.

A Simple Question May Flag Poor Quality Sleep

Asking adults how old they feel may help identify those at poor sleep risk. Adults who feel older than their age report more insomnia, poorer sleep regularity, and greater sleep-related impairment.

Can Chemoradiation Improve Outcomes in Pancreatic Cancer?

New data suggest adding chemoradiotherapy to adjuvant gemcitabine does not improve overall survival after pancreatic cancer resection, but one subgroup appears to benefit.

Multiple Clinical Factors Tied to Poor Bipolar Med Adherence

A meta-analysis identifies key clinical and sociodemographic factors linked to poor psychopharmacologic treatment adherence in adults with bipolar disorder.

Does High-Dose Omega-3 Benefit Cognition in Older Adults?

High-dose omega-3 supplements reach the brain but offer no cognitive benefits in older adults at high-risk for Alzheimer’s disease, a new trial suggests.

Monoclonal Antibodies May Complicate Transfusion Testing

Monoclonal antibody-based therapies can affect the results of transfusion tests, potentially leading to dangerous misinterpretations of the findings.

Pneumococcal Vaccine Extended to High-Risk Children, Teens

FDA approves expanded indication for individuals aged 2-17 years with chronic medical conditions.

FDA Delays iPLEDGE Modifications Until November 2026

FDA Delays iPLEDGE modification implementation until November 15, 2026, to allow additional time to test system updates, minimize technical glitches.

AI Predicts Abiraterone Benefit in High-Risk Prostate Cancer

A multimodal AI model identified a subset of men with very high-risk localized prostate cancer who derived substantial benefit from adding abiraterone to standard therapy.

AI in Gastroenterology: Benefits, Risks, and Safeguards

In gastroenterology, LLMs can draft notes, summarize data, and assist with patient messaging but can also err, introduce bias, or compromise privacy.

Clinicians Get New Rules for Prescribing Weight-Loss Drugs

The guidance still centers on lifestyle changes but recognizes the progress made in pharmacologic treatments for overweight and obesity.

What Space Travel Teaches Us About Cancer Biology

Could low-orbit microgravity accelerate cancer research on Earth? Prof David Kerr unpacks a Lancet Oncology study on the ISS as a cancer biology platform.

AI's Prescription for Moral Injury

George Lundberg, MD, asked an LLM how to cope with the profound moral distress of our era. The algorithm’s surprisingly grounding advice might help you, too.

Why Readiness Is Not a Prerequisite for Lifestyle Change

Dr Padmaja Patel challenges the idea that lifestyle interventions only work for motivated patients, offering tips on how motivation can be built in the clinical setting.

ASM Levels Equivalent in Maternal and Cord Blood

Antiseizure medication levels in maternal and cord blood at delivery are similar in pregnant women with epilepsy, indicating significant placental passage, a study shows.

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