Possible treatment for hemophilia

Published Date: 13 Mar 2023

Hemophilia A is a rare bleeding disorder caused by a genetically encoded factor VIII mutation that affects blood clotting. sick...

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Congo's Ebola Outbreak Spreads to New Health Zones

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HIV Care Coordination Program May Reduce Deaths in NYC

New York City’s revised Care Coordination Program may help reduce risks for all-cause and HIV-related deaths among people with HIV infection, including those at the highest risk for poor outcomes.

Teplizumab Approved for Pediatric Stage 3 Type 1 Diabetes

The drug was previously approved for stage 2 T1D.

One in Four Teen Girls and Young Women at Risk for PMOS

Findings suggest young females should be assessed and, if at risk, monitored.

Palopegteriparatide Benefits Sustained Beyond 3 Years

Final results from the PaTHway trial show the long-acting parathyroid hormone therapy enabled patients with hypoparathyroidism to achieve independence from high-dose calcium and vitamin D supplements.

Testosterone Prescribing Often Ignores Guidelines

Only 12% of patients prescribed testosterone underwent appropriate diagnostic testing, and overprescribing was common in a single-center US study.

Encaleret Shows Rapid Response in ADH1

The oral modulator of the calcium-sensing receptor targets the causes of ADH1, significantly improving serum and urine calcium levels.

Off-Label Rxs: Thinking Out of the Box for Skin Diseases

Off-label alternatives for FDA-approved therapies can be as effective, cheaper, and in some cases safer despite never having been submitted for regulatory approval.

Latest News

Analysis of electronic health record data shows unhoused patients with diabetes have more severe diabetic retinopathy and higher rates of vision-threatening complications than stably housed patients.

Congo's Ebola outbreak has spread ⁠to three new health zones, according to ⁠a government report published on Thursday that ⁠showed the ‌number of confirmed cases had risen...

India's drug price regulator raised ceiling rates for two key platinum-based cancer drugs by 50% after a surge ⁠in raw material costs triggered widespread shortages,...

Even though the real-world patients in a phase 4 study were older and heavier, ublituximab provided safety and tolerability at least comparable to that in 2 pivotal trials.

Congo's Ebola outbreak has spread to a new health zone in the northeastern ⁠province of Ituri, authorities said on Wednesday, as fresh infections underline sustained...

A cold snap that hit hundreds of thousands showed how quickly hospitals can lose order, with radiology calling for empathy, leadership, and real disaster protocols.

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Psilocybin May Boost Abstinence in Cocaine Use Disorder

Psilocybin added to psychotherapy is associated with a greater likelihood of abstinence in cocaine use disorder than an adjunct active placebo, a study shows.

Ebola Recoveries Bring Signs Of Hope in DRC as Suspected Cases Emerge Outside Africa

Four nurses who were being treated for Ebola caused by the Bundibugyo strain of the virus have been discharged from a hospital in Bunia in the Democratic ⁠Republic of Congo...

Dual Pulmonary Hypertension Therapy Safer for Angioplasty

Dual therapy for pulmonary hypertension before balloon pulmonary angioplasty is linked to fewer thoracic complications than monotherapy in patients with chronic thromboembolic pulmonary hypertension.

Eye Inflammation Tied to Anti-Adalimumab Antibody Formation

Patients with autoimmune diseases who experience ocular inflammation while on adalimumab have an increased risk of developing antibodies against the drug, according to a recent retrospective study.

Ralinepag Offers Once Daily Oral Option for PAH

Phase 3 data provide the foundation for a planned New Drug Application.

Suspected and Confirmed Measles Deaths Top 500 in Bangladesh

It's one of the country's worst outbreaks in decades.

Experimental Treatments Could Help US Ebola Patient

The U.S. missionary who tested positive for Ebola and is undergoing treatment in a German hospital has been given drugs aimed at reducing disease symptoms after exposure to...

WHO Chief Says Fast-moving Ebola Epidemic Is Outpacing Response Efforts

The head of the World Health Organization said on Monday that the ⁠fast-moving Ebola outbreak in Democratic Republic of Congo and Uganda was outpacing response ⁠efforts,...

Pill for Obstructive Sleep Apnea Shows Potential

AD109 works by targeting neuromuscular dysfunction of upper airway muscles during sleep, representing a potential new strategy to help people with obstructive sleep apnea.

Accuracy of Proposed CTE Diagnostic Criteria Questioned

Most individuals who meet proposed clinical criteria for chronic traumatic encephalopathy lack the disease’s hallmark pathology at autopsy, raising questions about the criteria’s diagnostic reliability.

EMA OKs New Option for Pulmonary Fibrosis

The oral therapy is intended for adults with idiopathic pulmonary fibrosis or progressive pulmonary fibrosis, two fibrotic lung diseases with limited treatment options.

Higher Caffeine Intake Tied to Greater Depression Severity

Insomnia, sleepiness, fatigue, and stress were associated with higher depression scores, but caffeine appeared to lessen the association between depression and severe insomnia.

First Real-World Study Supports Sotatercept for PAH

Researchers share their experience with sotatercept in 91 patients with pulmonary arterial hypertension, the first report on outcomes outside clinical studies.

Air Pollution Linked to Reduced Midlife Cognitive Function

Everyday exposure to traffic, industry, and wildfire smoke was associated with vascular brain injury in middle age.

Perinatal Grief and Disney’s Versa: Can Films Change Care?

Spanish clinicians and grief advocates stress that compassionate communication and bereavement support shape how families process perinatal loss.

Self-Screening Tool for AxSpA Aims to Lower Diagnostic Delay

The patient self-screening tool that was developed to help identify axial spondyloarthritis promises to cut time to diagnosis and is being evaluated in a large European cohort.

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