Identifying pathogenic proteins leads to potential new treatments for diseases such as diabetes.

Published Date: 02 Mar 2023

New research has identified hundreds of proteins that can lead to the development of metabolic diseases, such as type 2 diabetes mellitus, and therefore have treatment potential.

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Standalone Traumatic Brain Injuries Rarely Lead to Chronic Traumatic Encephalopathy Development Enna Selmanovic, Louie Pasculli

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Semaglutide Provides Cardiorenal Benefits in CKD With or Without Diabetes

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Researchers from the German Cancer Research Center and the University of Freiburg show how certain painkillers influence the iron metabolism of liver cancer cells and can thus contribute to iron deficiency and anemia in cancer ...

For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease. But a critical question remained: do the failing mitochondria cause Parkinson's, or do they ...

For most women, menopause occurs naturally around the age of 49. In the lead up to menopause, the quality and quantity of eggs declines over time. Then the ovaries stop releasing eggs completely.

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Lactulose and tai chi show promise preventing falls for cirrhosis patients

Lactulose and tai chi can prevent falls in patients with cirrhosis, according to results from the LiveSMART Trial. Michigan Medicine hepatologists reported the findings as a late breaking abstract at The Liver Meeting 2025 ...

Nutritional supplement could help with fat metabolism activation therapies

Dr. Ann Coulter of Pennington Biomedical Research Center recently presented research on a novel nutritional supplement that targets fat cells to stimulate weight loss at the Bio on the Bayou conference in New Orleans.

Early-life ketone signaling may shape long-term metabolic health

In a major advance in metabolic research, scientists from National Taiwan University have discovered that ketone bodies produced naturally during the lactation period are not merely an alternative fuel, but act as powerful ...

Sleep-related disorders associated with hypertension in postmenopausal women

Postmenopausal women are especially vulnerable to hypertension, which is a major cardiovascular risk factor. Women transitioning through or past the menopause transition are also more likely to report sleep disturbances (shorter ...

Experimental drug protects mitochondria and prevents kidney injury in mice

Serious damage to short-term kidney function—known as acute kidney injury, or AKI—can be fatal and also increase the risk of irreversible chronic kidney disease. It can be triggered by stressors ranging from sepsis to ...

Blocking gene improves metabolic health in obese mice without weight loss

Weill Cornell Medicine investigators have identified an early step in a cellular process that leads to inflammation in fat cells and may result in type 2 diabetes in people with obesity.

The flexible brain: How circuit excitability and plasticity shift across the day

Our brains do not react in a fixed, mechanical way like electronic circuits. Even if we see the same scene every day on our commute to work, what we feel—and whether it leaves a lasting impression—depends on our internal ...

Estrogen's role in boosting dopamine and cognition: Experiments uncover how hormones influence learning

Researchers have long established that hormones significantly affect the brain, creating changes in emotion, energy levels, and decision-making. However, the intricacies of these processes are not well understood.

Cutting key amino acids from mouse diets triggers weight loss through heat burning

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Routine use of metabolic drug recommended for all kidney function levels

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Urolithin A nudges aging immune cells toward a youthful profile in 28 days

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Why morning exercise feels so hard

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Widely used pesticides may lower sperm count

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Missing enzyme may explain impaired bone growth

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