Metformin changes blood metal levels in humans, offering further insight into its mechanism of action

Published Date: 01 Sep 2025

The widely used diabetes drug metformin changes blood metal levels in humans. The Kobe University study is an important step in understanding the drug's many actions and designing better ones in the future.

Read Full News

Latest News

Do fatalistic attitudes affect clinical outcomes in type 2 diabetes?

University of Wisconsin-Milwaukee and University at Buffalo investigators report that diabetes fatalism is associated with lower mental health-related quality of life over 12 months in African American adults with poorly ...

Big sex differences found in how diet and insulin rewire muscle for better blood sugar

New research found that restricting calories dramatically rewires proteins in rat skeletal muscle, causing molecular changes that boost insulin sensitivity—crucial for blood sugar control in older adults, say scientists ...

Normalizing blood sugars could cut type 2 diabetes risk in half

Prediabetes has long been thought to lead to type 2 diabetes, but according to new Deakin research, for some that isn't always the case.

Why type 1 diabetes is more aggressive in young children

Scientists have made a major breakthrough in understanding why type 1 diabetes is more aggressive in young children, offering the clearest explanation to date of why the condition is particularly difficult to manage when ...

One-hour blood glucose level: A better chance to prevent diabetes

An elevated blood glucose level one hour after the oral glucose tolerance test (OGTT) signals a critical metabolic state—even before prediabetes. Affected individuals respond particularly well to lifestyle interventions. ...

Oral insulin trial marks milestone toward personalized prevention of type 1 diabetes

The Primary Oral Insulin Trial (POInT) investigates whether type 1 diabetes in at-risk children can be prevented through oral insulin treatment. First results mark an important step toward the prevention of type 1 diabetes, ...

Todays Updates

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

Nurses Speak Out on Burnout, Mandatory Overtime, and Burning the Candle at Both Ends

Emotionally drained, sleep-deprived, and skipping meals to keep up: what nurse leaders say needs to change to prevent burnout.

Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

Bloating is one of patients' most common gastrointestinal complaints. Dr Alicia Muratore kicks off this six-part series by asking why bloating is often treated as an afterthought.

S1 Episode 4: Urinary Tract Infections and Sexual Function

Drs Anne Lenore Ackerman and Rachel S. Rubin discuss urinary tract infections, sexual function, quality of life, and the importance of patient education.

Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

State telehealth coverage parity laws require private insurers to cover outpatient telehealth visits increasing access for HF patients. This analysis examines whether this affected clinical outcomes.

Todays Updates

Many Clinical Paths Are Open to NPs. Here’s Help in Picking

‘A strength of the nurse practitioner profession is its versatility,’ one expert says.

Nurses Speak Out on Burnout, Mandatory Overtime, and Burning the Candle at Both Ends

Emotionally drained, sleep-deprived, and skipping meals to keep up: what nurse leaders say needs to change to prevent burnout.

Most Family Physicians Struggle With After-Hours Admin Work

Most family physicians face heavy administrative burden, but improved electronic health records and staff support may help to ease some of the load.

'Just Bloating': Stop Dismissing This Common GI Complaint

Bloating is one of patients' most common gastrointestinal complaints. Dr Alicia Muratore kicks off this six-part series by asking why bloating is often treated as an afterthought.

S1 Episode 4: Urinary Tract Infections and Sexual Function

Drs Anne Lenore Ackerman and Rachel S. Rubin discuss urinary tract infections, sexual function, quality of life, and the importance of patient education.

Immunotherapy Promises New Era in Cancer Prevention

Prof David Kerr explores whether PD-1 inhibitors and targeted vaccines can regress polyps and prevent secondary cancers in Lynch syndrome.

HF Hospitalizations and Telehealth Coverage Parity Laws

State telehealth coverage parity laws require private insurers to cover outpatient telehealth visits increasing access for HF patients. This analysis examines whether this affected clinical outcomes.

Latest News

University of Wisconsin-Milwaukee and University at Buffalo investigators report that diabetes fatalism is associated with lower mental health-related quality of life over 12 months in African American adults with poorly ...

New research found that restricting calories dramatically rewires proteins in rat skeletal muscle, causing molecular changes that boost insulin sensitivity—crucial for blood sugar control in older adults, say scientists ...

Prediabetes has long been thought to lead to type 2 diabetes, but according to new Deakin research, for some that isn't always the case.

Scientists have made a major breakthrough in understanding why type 1 diabetes is more aggressive in young children, offering the clearest explanation to date of why the condition is particularly difficult to manage when ...

An elevated blood glucose level one hour after the oral glucose tolerance test (OGTT) signals a critical metabolic state—even before prediabetes. Affected individuals respond particularly well to lifestyle interventions. ...

The Primary Oral Insulin Trial (POInT) investigates whether type 1 diabetes in at-risk children can be prevented through oral insulin treatment. First results mark an important step toward the prevention of type 1 diabetes, ...

News All Time

Finerenone reduces kidney damage in type 1 diabetes by lowering protein in urine

The drug finerenone has a positive effect on patients with type 1 diabetes and chronic kidney disease. The drug reduces the amount of proteins excreted in the urine of these patients. This reduction indicates that the degree ...

Therapies against cellular aging may help treat metabolic diseases

A growing body of evidence implicates cellular senescence—when cells age and permanently stop dividing—as an important contributor to metabolic dysfunction that can lead to obesity, type 2 diabetes, and metabolic syndrome.

Real-time glucose monitoring with professional support can improve type 1 diabetes control

People with type 1 diabetes achieved significantly better long-term blood glucose when their levels were monitored by health care professionals in real time, via a sensor under the skin, and they received regular advice in ...

Evolutionary comparison points to pigs as superior models for human pancreas and diabetes research

Pancreas development in pigs resembles humans much more closely than does the established mouse model. An international team headed by Helmholtz Munich and the German Center for Diabetes Research (DZD) has now produced a ...

Closed-loop insulin system improves glucose control during pregnancy, clinical trial finds

A collaborative effort across 14 clinical centers in Canada and Australia reports that pregnant women with type 1 diabetes using a closed-loop insulin system spent more time in the pregnancy-specific glucose range than those ...

Healthy lifestyle combined with newer diabetes medications lowers cardiovascular risk, preliminary study suggests

People with type 2 diabetes who combined healthy lifestyle habits with GLP-1 receptor agonist (GLP-1 RA) medications had a greater reduction in risk of major adverse cardiovascular events, including heart attack, stroke or ...

Cartoon-based diabetes education can enhance children's knowledge and physical activity

Researchers at University of Tsukuba reported that using manga as an educational tool in diabetes instruction for children can be equally effective as traditional lectures in enhancing diabetes-related knowledge and engagement ...

New model shows how treating diabetes early makes a difference

Could slightly elevated blood sugar levels lead to serious health problems in the future? A single patient's question sparked nearly a decade of research leading to the development of a landmark model that could shape how ...

Researcher provides new hope in managing diabetic ketoacidosis

A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels in diabetic patients and increasing exercise capacity for better health outcomes. That could be ...

Chemists design candidate drug against diabetes

Researchers from the University at Albany and NYU Grossman School of Medicine have found a way to block a key cellular pathway known to drive chronic inflammation and impaired wound healing in people with diabetes.

Exercise-induced vesicles help protect pancreatic cells and guard against diabetes

Exercise is known for the positive effects on metabolic diseases, partly because of the release of circulating extracellular vesicles (EVs) that mediate intercellular communication and organ crosstalk.

AI-powered diabetes prevention program shows similar benefits to those led by people

Researchers from Johns Hopkins Medicine and the Johns Hopkins Bloomberg School of Public Health report that an AI-powered lifestyle intervention app for prediabetes reduced the risk of diabetes similarly to traditional, human-led ...

Bariatric surgery in a pill bottle

More than 37 million Americans have type 2 diabetes, a chronic disorder affecting the body's ability to regulate and use sugar. According to the CDC, it's the country's seventh leading cause of death. Type 2 diabetes can ...

Early trigger of diabetic eye disease identified

A team led by UCL scientists has identified a key protein that triggers diabetic retinopathy—a condition caused by high blood sugar damaging the retina's blood vessels and a leading cause of sight loss among working-age ...

African-Caribbean ethnicity key risk factor for sight-threatening diabetic eye disease

People of African-Caribbean ethnicity with Type 2 diabetes are a third more likely to develop a condition called sight-threatening diabetic retinopathy (STDR) than other ethnic groups, according to researchers from King's.

Remission achievable for 1 in 3 Indian diabetics through intensive app-based lifestyle program, study suggests

Nearly one-third of people with type 2 diabetes (T2D) in an Indian cohort have achieved remission through an intensive lifestyle intervention program, according to a study published in PLOS One by Pramod Tripathi of the Freedom ...

Recommended News For You

A Lot Can Be Said About You by Including Yourself in Photos.

More Support for Early Detection; Cancer in Men Rising; Diet Drives Colon Cancer

Belgian Algorithm Reshapes Endometrial Cancer Care

Renewing the call for a national Cancer Patient's Bill of Rights

Mosunetuzumab in Follicular Lymphoma: Durable Responses and Manageable Safety

Real-World EV Plus Pembro Success Seen in Urothelial Cancer

ctDNA Predicts Relapse in Locally Advanced Cervical Cancer

Recommended Articles For You

Understanding the Importance of Knowing Your MCV Normal Range 

Role of Type I Interferons and KDM1B in Driving Cancer Stemness and Therapeutic Evasion 

Thyroidectomy & Survival: Highlights from ASCO 2025 and Current U.S. Findings 

Gynecologic Oncology: Advances, Education, and Clinical Excellence 

Whats more on Hidoc Dr.

Medical Updates
KOL Videos
Surveys
Events

Daily news to keep you up to date

Gain valuable insights with our in-depth KOL Video discussions

Participate and win cash vouchers

Get updates on the latest events happening around the world
Featured News
Featured Articles
Featured Events
Featured KOL Videos

1.

New surgical method shows promising results for cervical cancer treatment

2.

Babies Are Bleeding to Death as Parents Reject a Vitamin Shot Given at Birth

3.

GuCS Future Focus: Future Focus from the Genitourinary Cancers Symposium

4.

Study confirms safety and efficacy of higher-dose-per-day radiation for early-stage prostate cancer

5.

Can Prior Authorization Be Better With Artificial Intelligence?

1.

Checkpoint Inhibitors in Oncology: Advances in PD-1/PD-L1 and CTLA-4 Targeted Therapy

2.

Public Health Strategies for Improving Cancer Survivorship Support Systems

3.

Analyzing the Mechanisms and Efficacy of Carboplatin, Abraxane, and Albumin-Bound Formulations

4.

Treating Methemoglobinemia: What You Need to Know Now!

5.

Red Cell Deformability as a Target in Critical Illness

1.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

2.

International Cancer Conference

3.

Asian Symposium on Advancement in Hematology and Oncology (ASAHO)

4.

Asian Symposium on Advancement in Hematology and Oncology

5.

Asian Symposium on Advancement in Hematology and Oncology

1.

Expert Group meeting with the management of EGFR mutation positive NSCLC - Part IV

2.

Managing CNS diseases at the point of diagnosis in ALK + NSCLC

3.

Understanding the Multifaceted Advantages of CDK4/6 Inhibitors in HR+/HER2- PALOMA 2 Study.

4.

Revolutionizing Treatment of ALK Rearranged NSCLC with Lorlatinib - Part II

5.

Updates on Standard V/S High Risk Myeloma Treatment


Fastest Growing Medical Platform for Doctors

Address :
Hidoc Dr. Inc. | Delaware C Corp | 1309 Coffeen Ave. Suite 1200, Sheridan WY, 82801

Phone :
+1-415-463-3094

Email :
anishagadia@hidoc.co

Quick Links

Drug DatabaseDrug InteractionDiseases Database
KOL VideosKnowledge HubQuizzes
Medical UpdatesEventsAbout Us

© Copyright 2026 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
Home
Profile
Login
bot