A mouse study reveals a connection between dementia risk and cold frequency.

Published Date: 05 Apr 2023

Being ill frequently may slow down brain aging and raise the risk of dementia and other forms of cognitive decline.

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Todays Updates

Faster 1-Hour MI Rule-Out Is Safe

The 1-hour troponin pathway was safely implemented in a real-world study but did not impact workflow in busy emergency departments.

Edoxaban Falls Short After Intracranial Hemorrhage in AF

Edoxaban reduced ischemic stroke after intracranial hemorrhage in patients with AF, but excess hemorrhagic stroke and major bleeding offset the benefit.

Drug Benefit Seen in Nonobstructive HCM

A multicenter phase 3 trial has associated a cardiac myosin inhibitor with meaningful clinical benefit in nonobstructive HCM, for which there has been no effective therapies.

Tailored Approach Shortens Endocarditis Therapy

Tailored antibiotic therapy for infective endocarditis was associated with a significant reduction in treatment duration, according to an open-label multicenter trial.

Latest News

Capricor Therapeutics said on Monday the U.S. Food and Drug Administration had extended the review period for ⁠its experimental cell therapy for Duchenne muscular dystrophy...

A reanalysis of lecanemab and donanemab trials suggests cognitive decline accelerates in open-label extensions, matching placebo rates, and challenging claims that cognitive benefits increase over time.

A novel spectacle lens design featuring aspherical lenslets reduced myopia progression in children by more than 70% compared with standard single-vision lenses over 24 months.

Evidence for the effect of THC on seizure threshold is conflicting, clinicians say

— Chlorpyrifos and other organophosphate insecticides had no association at low exposure levels

Louisiana experienced its first confirmed Naegleria fowleri infection since 2013

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Triple reuptake inhibitor centanafadine is indicated for patients ages 6 years and older

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Agency says deramiocel did not meet phase III trial endpoints, contrary to reported data

Feds Delay Autism Meeting; Wildfire Smoke and Migraine; Mortality and MS

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Sugar Rationing in Early Life Linked to Lower Dementia Risk Decades Later

Long-term study looks at what happened when sugar was scarce

FDA Committee Votes Down Duchenne Drug

Agency staff and drug developer disagree on endpoints

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Fauci Successor Imminent; CDC Expands Outbreak List; Pesticides Linked to ALS

Health news and commentary gathered by MedPage Today staff

FDA Approves First-in-Class Narcolepsy Drug

Oveporexton treats more than symptoms, restores orexin signaling

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News and commentary from the world of neurology and neuroscience

Trump Issues Controversial Order on Vaccines, Suggests Autism Link

Order calls for MMR vaccine to be split up, given at separate medical appointments

Pet Hamsters Linked to Rare Brain Disorder

Exposure was associated with autoimmune cerebellar ataxia in a hospital case-control study

CDC Warns of Severe Arboviral Disease With B-Cell Drugs

Cases have included chronic, neurodegenerative encephalitis that played out over months to years

Fact Focus: Trump's False Claims During Childhood Vaccine Order Signing

A closer look at the president's assertions

Trump's Vax Order Hands Some MAHA Voters a Win, but Gives Democrats an Attack Line

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CDC's Zombie Programs: Congress Funds Them, but Few People Are Left to Do the Work

Democrats say what's happening is illegal

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