Is Alzheimer's disease, relentless and slow, a better target for clinical trials?

FAST-Forward Trial Confirms 1-Week Breast RT at 10 Years

After a decade of follow-up, a 1-week RT regimen remains noninferior to standard treatment for early breast cancer, with similar rates of recurrence and long-term adverse events.

Vibrating Ingestible Capsule Flags Anorexia Relapse Risk

A vibrating capsule identifies subtle deficits in gut-brain signaling that are associated with relapse 6 months after weight restoration in anorexia nervosa.

ADHD Diagnosis Gap Persists, Below Prevalence in England

Attention-deficit/hyperactivity disorder diagnosis rates in England remain markedly below global prevalence estimates for all age groups, with varying gaps between diagnoses and published estimates.

Poor Teen Sleep Tied to Worse Adult Health

Outpatients Prescribed Antibiotics for Simple Diverticulitis

Practice at Veterans Affairs healthcare facilities runs counter to a decade-old AGA guideline reserving antibiotics for select diverticulitis patients only.

Hundreds Harmed by Nottingham Maternity Services

Donna Ockenden's 3-year review finds a bullying culture and deep-rooted failures at Nottingham University Hospitals led to the needless deaths and harm of more than 500 mothers and babies.

Combination Therapy Boosts Remission in Ulcerative Colitis

In patients with ulcerative colitis, endoscopic remission rates are more than twofold higher after an induction with upadacitinib plus vedolizumab vs vedolizumab monotherapy.

The Force Is With You: How Trust Shapes Cancer Care

Oncologists spend years learning to trust their own judgment, an ability that marries intuition with reasoning. What happens to that hard-won skill when AI starts doing the pattern-matching for them?

Youth Who Get Smartphones at 13 Likely to Face Health Issues

Smartphone acquisition at 13 years of age is linked to insufficient sleep at 14 years of age; a greater duration of use is associated with higher risks for depression, obesity, and insufficient sleep.

NHS Trusts Unable to Account for £400m of Training Cash

A BMJ investigation finds nearly £400 million of NHS funding for medical student placements is unaccounted for — and mandatory reporting has now been dropped.

Diagnosing Alpha-Gal Syndrome in Children

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

High Blood Pressure? Consider the Aldosterone Connection

Less than 1% of patients with primary aldosteronism are diagnosed. The Curbsiders are here to help change that with practical screening and treatment tips.

Social Anxiety Disorder Surging in Canada

Social anxiety disorder is now one of the most common mental health challenges in Canada, with a 71% increase in prevalence since 2002.

Trading Cigarettes for Vapes May Still Be Harmful for Vision

Former cigarette smokers who switch to noncombustible nicotine or tobacco products have a higher risk for major vision-impairing eye diseases than those who quit tobacco and nicotine entirely.

Can a Constipation Drug Clear Depression’s ‘Brain Fog’?

A proof-of-concept study suggests the 5-HT4 receptor agonist prucalopride, which is approved for chronic constipation, improves cognition in patients with remitted depression.

GPs Urged to Screen for Gambling During World Cup

Clinicians are urging GPs to treat gambling harm with the same routine scrutiny as alcohol and tobacco misuse, as World Cup gambling activity peaks.