Is Alzheimer's disease, relentless and slow, a better target for clinical trials?

Published Date: 16 Feb 2023

According to a report by the Alzheimer's Association task force, it's time to reframe what "clinically meaningful" means and change expectations about clinical trials.

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The Hopkins protocol may have solved one of the biggest problems in reduced-intensity sickle cell transplant — graft failure in children — with the added bonus of preserving fertility.

Although a new phase 2 study missed its primary endpoint, the anti-tau therapy diranersen reduces tau pathology and shows signs of slowing clinical decline in early AD.

Structural inequities and lack of information may keep patients from getting the therapies.

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