Breast cancer is very expensive around the world.

Published Date: 16 Feb 2023

Study documents huge financial costs of breast cancer treatment for women in high and low/middle income countries and offers opportunities for intervention.

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EU Agrees Draft Deal to Tackle Essential Medicine Shortages

European Union lawmakers and member states reached a provisional deal on Tuesday to strengthen the bloc's supply ⁠of essential medicines by boosting domestic production and...

Free Birth Movement Presents Ethical Quandary: Ethicist

Art Caplan discusses the medical ethics involved in a free birth that went terribly wrong.

Obesity Management After Unsuccessful Dieting

A 45-year-old woman with a BMI of 38 kg/m2 presents with obesity despite lifestyle modifications. This case discussion on obesity highlights management strategies with novel incretin-based therapies.

The Ivermectin Paradox in Oncology

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Only 1 in 4 Eligible Adults Receive Lung Screening

Complicated eligibility rules, stigma surrounding smoking and lung cancer, and confusion about the screening process continue to keep many high-risk patients from getting screened.

Low PSA May Not Fully Predict Survival in Prostate Cancer

A recent post hoc analysis assesses whether PSA changes can predict survival outcomes in patients with metastatic or very high risk nonmetastatic prostate cancer.

FDA Warns of Secondary Blood Cancer Risk With Tazverik

The FDA says the increased risk of hematologic secondary primary malignancies with tazemetostat now outweighs the benefits of the drug; Ipsen pulls it from the market.

FDA Approves Next-Gen Agent for Mantle Cell Lymphoma

The BCL-2 inhibitor was granted accelerated approval based on findings from the phase 1/2 BGB-11417-201 study.

Todays Updates

Only 1 in 4 Eligible Adults Receive Lung Screening

Complicated eligibility rules, stigma surrounding smoking and lung cancer, and confusion about the screening process continue to keep many high-risk patients from getting screened.

Low PSA May Not Fully Predict Survival in Prostate Cancer

A recent post hoc analysis assesses whether PSA changes can predict survival outcomes in patients with metastatic or very high risk nonmetastatic prostate cancer.

FDA Warns of Secondary Blood Cancer Risk With Tazverik

The FDA says the increased risk of hematologic secondary primary malignancies with tazemetostat now outweighs the benefits of the drug; Ipsen pulls it from the market.

FDA Approves Next-Gen Agent for Mantle Cell Lymphoma

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European Union lawmakers and member states reached a provisional deal on Tuesday to strengthen the bloc's supply ⁠of essential medicines by boosting domestic production and...

Art Caplan discusses the medical ethics involved in a free birth that went terribly wrong.

A 45-year-old woman with a BMI of 38 kg/m2 presents with obesity despite lifestyle modifications. This case discussion on obesity highlights management strategies with novel incretin-based therapies.

Dr Arturo Loaiza-Bonilla examines the gap between ivermectin’s lab data and clinical reality, offering a guide to debunking ‘miracle cure’ myths while maintaining patient trust.

Two studies take different approaches to improving constipation, one examining the influence of TikTok and the other examining the effect of physical positioning.

As peptides for wellness surge in popularity, two safety groups warn many users may be injecting unapproved substances with little evidence they are safe or effective.

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Genotype-Guided SSRI Prescribing Offers Mixed Results

Use of genotype-guided SSRI shows no symptom improvement at 3 months in people with depression but is linked to higher remission rates at 6 months.

Ultraprocessed Food Linked to Increased Dementia Risk

High consumption of heavily processed foods is linked to increased dementia risk and lower attention in midlife, irrespective of adherence to a healthy diet, a study shows.

CGRP Inhibitors for Migraine Linked to Reduced Glaucoma Risk

The use of calcitonin gene-related peptide (CGRP) inhibitors to treat adults with migraine is linked to a 25% lower risk for glaucoma than the use of non-CGRP inhibitors, a new study shows.

Real-World Use of Upadacitinib Effective in Perianal Crohn's

Upadacitinib is effective in inducing clinical response and remission and is generally well tolerated in patients with perianal Crohn's disease, a real-world study shows.

Once Daily, 10 Minute Rehab Maybe Be Enough in Mild Stroke

Just 10 min of daily early mobility training may suffice for patients with mild stroke, but those with moderate stroke may benefit from two daily sessions, as per results from the AVERT DOSE trial.

Does Vaping Cause Cancer?

A sweeping research review says that e-cigarettes likely contribute to cancer risk, based on biomarker, animal, and mechanistic data — but definitive evidence could take many more years.

NordICC 13-Year Update: Colonoscopy Curbs CRC; Deaths Stable

Updated data from the NordICC trial are consistent with previous results, while subgroup analyses provide new insights.

Intrusive Memories Tied to Cravings in Cocaine Use Disorder

Real-time data reveal that intrusive memories of drug use often occur without craving but can drive its intensity, suggesting new targets for psychotherapy in cocaine use disorder.

Early Antiviral Prophylaxis Reduces Nursing Home Admissions

A US study found that giving oseltamivir to ≥ 70% of nursing home residents within 48 hours of an outbreak cut hospitalizations — but German logistics may hinder rapid rollout.

Gastric Sleeve Endoscopy Continues Weight Loss after GLP-1s

Researchers link the minimally invasive procedure to significantly greater total weight loss compared to lifestyle modification alone at 1 year after stopping GLP-1 therapy.

NICE Recommends Givinostat for Duchenne Muscular Dystrophy

NICE has recommended givinostat for all DMD types, offering around 530 patients a drug that may delay disease progression by up to 5 years.

DEI Bans Won’t Erase Health Disparities

Dr George Lundberg explains why treating equity as a banned political buzzword undermines the very foundations of public health and medical care.

Tegoprazan TRIUMpHs Over PPI For Erosive Esophagitis

Tegoprazan is superior to the proton pump inhibitor lansoprazole for healing erosive esophagitis as early as week 2, but one expert finds these results underwhelming.

Second Cancer Rates Vary Widely Among Survivors

Not all cancer survivors face the same likelihood for a second cancer. New data show striking differences by age, cohort, and initial diagnosis.

Q&A: Progress in Thwarting ‘Chemobrain’

Recent trials suggest that simple steps during chemotherapy — including moderate exercise and a daily ibuprofen — may lessen treatment-related cognitive symptoms.

Digital NHS Risks Leaving Older Patients Behind

Older people lack the skills, devices, or support to book GP appointments online — and many are giving up on trying.

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