Paxlovid does not increase risk of COVID reinfection: study

Published Date: 16 Feb 2023

Although there are concerns that the use of Paxlovid increases the risk of COVID-19 returning, the results are clear.

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In patients with ulcerative colitis, endoscopic remission rates are more than twofold higher after an induction with upadacitinib plus vedolizumab vs vedolizumab monotherapy.

Oncologists spend years learning to trust their own judgment, an ability that marries intuition with reasoning. What happens to that hard-won skill when AI starts doing the pattern-matching for them?

Smartphone acquisition at 13 years of age is linked to insufficient sleep at 14 years of age; a greater duration of use is associated with higher risks for depression, obesity, and insufficient sleep.

A BMJ investigation finds nearly £400 million of NHS funding for medical student placements is unaccounted for — and mandatory reporting has now been dropped.

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

Less than 1% of patients with primary aldosteronism are diagnosed. The Curbsiders are here to help change that with practical screening and treatment tips.

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Novel Narcolepsy Drug Delivers Benefits Beyond Wakefulness

The oral orexin receptor 2 agonist improved cognitive performance, daily functioning, and work productivity in addition to wakefulness and cataplexy control, new phase 3 data show.

US Doctors Seek Better Working Conditions in Canada

US doctors are emigrating to Ontario, British Columbia, and Nova Scotia in response to increasing healthcare bureaucracy and political tensions at home.

A Simple Question May Flag Poor Quality Sleep

Asking adults how old they feel may help identify those at poor sleep risk. Adults who feel older than their age report more insomnia, poorer sleep regularity, and greater sleep-related impairment.

Can Chemoradiation Improve Outcomes in Pancreatic Cancer?

New data suggest adding chemoradiotherapy to adjuvant gemcitabine does not improve overall survival after pancreatic cancer resection, but one subgroup appears to benefit.

Multiple Clinical Factors Tied to Poor Bipolar Med Adherence

A meta-analysis identifies key clinical and sociodemographic factors linked to poor psychopharmacologic treatment adherence in adults with bipolar disorder.

Does High-Dose Omega-3 Benefit Cognition in Older Adults?

High-dose omega-3 supplements reach the brain but offer no cognitive benefits in older adults at high-risk for Alzheimer’s disease, a new trial suggests.

Monoclonal Antibodies May Complicate Transfusion Testing

Monoclonal antibody-based therapies can affect the results of transfusion tests, potentially leading to dangerous misinterpretations of the findings.

Pneumococcal Vaccine Extended to High-Risk Children, Teens

FDA approves expanded indication for individuals aged 2-17 years with chronic medical conditions.

FDA Delays iPLEDGE Modifications Until November 2026

FDA Delays iPLEDGE modification implementation until November 15, 2026, to allow additional time to test system updates, minimize technical glitches.

AI Predicts Abiraterone Benefit in High-Risk Prostate Cancer

A multimodal AI model identified a subset of men with very high-risk localized prostate cancer who derived substantial benefit from adding abiraterone to standard therapy.

AI in Gastroenterology: Benefits, Risks, and Safeguards

In gastroenterology, LLMs can draft notes, summarize data, and assist with patient messaging but can also err, introduce bias, or compromise privacy.

Clinicians Get New Rules for Prescribing Weight-Loss Drugs

The guidance still centers on lifestyle changes but recognizes the progress made in pharmacologic treatments for overweight and obesity.

What Space Travel Teaches Us About Cancer Biology

Could low-orbit microgravity accelerate cancer research on Earth? Prof David Kerr unpacks a Lancet Oncology study on the ISS as a cancer biology platform.

AI's Prescription for Moral Injury

George Lundberg, MD, asked an LLM how to cope with the profound moral distress of our era. The algorithm’s surprisingly grounding advice might help you, too.

Why Readiness Is Not a Prerequisite for Lifestyle Change

Dr Padmaja Patel challenges the idea that lifestyle interventions only work for motivated patients, offering tips on how motivation can be built in the clinical setting.

ASM Levels Equivalent in Maternal and Cord Blood

Antiseizure medication levels in maternal and cord blood at delivery are similar in pregnant women with epilepsy, indicating significant placental passage, a study shows.

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