Paxlovid does not increase risk of COVID reinfection: study

Published Date: 16 Feb 2023

Although there are concerns that the use of Paxlovid increases the risk of COVID-19 returning, the results are clear.

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Growing Shortage of Pediatric Healthcare Workforce

A profound shortage of pediatric healthcare professionals threatens children's health.

Precompetition Abstinence: Evidence Challenges Myth

Published findings suggest clinicians should avoid blanket abstinence and offer individualized, stigma-free guidance on sleep and recovery for competitive athletes.

Longer Colonoscopy Time May Improve Flat Adenoma Detection

Examining the proximal colon for 3 minutes or longer during screening colonoscopy may improve detection of flat adenomas.

How Nanotech Made an Old Leukemia Drug 22,000x Stronger

Structural nanomedicine — what helped give us the COVID vaccine — may now be the key to a potent blood cancer treatment that’s had remarkable early results.

Medium-Chain Triglycerides Can Improve Quality of Life in RA

Incorporating medium-chain triglycerides into the regular diet of patients with rheumatoid arthritis can improve their mental well-being and social functioning, a 16-week randomized trial shows.

Zongertinib Picks Up First-Line Metastatic NSCLC Indication

The accelerated approval for patients with HER2 (ERBB2)-mutated disease follows an approval last August for use after prior systemic therapy.

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Immunotherapy Remains Little Used in Head and Neck Cancer

Immune checkpoint inhibitors have been FDA-approved for head and neck cancer for a decade, but their use has only marginally increased among patients younger than 65.

EVP Beats Cisplatin for Resectable MIBC

As the first chemotherapy-free regimen to beat gemcitabine/cisplatin, perioperative enfortumab vedotin plus pembrolizumab could shift muscle-invasive bladder cancer care — but questions remain.

Belzutifan Combo Could be Second-Line Option in Advanced RCC

Belzutifan plus lenvatinib significantly improves outcomes vs single agent cabozantinib in patients with advanced RCC who progressed after anti-PD-(L)1 therapy, new data show.

Todays Updates

Immunotherapy Remains Little Used in Head and Neck Cancer

Immune checkpoint inhibitors have been FDA-approved for head and neck cancer for a decade, but their use has only marginally increased among patients younger than 65.

EVP Beats Cisplatin for Resectable MIBC

As the first chemotherapy-free regimen to beat gemcitabine/cisplatin, perioperative enfortumab vedotin plus pembrolizumab could shift muscle-invasive bladder cancer care — but questions remain.

Belzutifan Combo Could be Second-Line Option in Advanced RCC

Belzutifan plus lenvatinib significantly improves outcomes vs single agent cabozantinib in patients with advanced RCC who progressed after anti-PD-(L)1 therapy, new data show.

Latest News

A profound shortage of pediatric healthcare professionals threatens children's health.

Published findings suggest clinicians should avoid blanket abstinence and offer individualized, stigma-free guidance on sleep and recovery for competitive athletes.

Examining the proximal colon for 3 minutes or longer during screening colonoscopy may improve detection of flat adenomas.

Structural nanomedicine — what helped give us the COVID vaccine — may now be the key to a potent blood cancer treatment that’s had remarkable early results.

Incorporating medium-chain triglycerides into the regular diet of patients with rheumatoid arthritis can improve their mental well-being and social functioning, a 16-week randomized trial shows.

The accelerated approval for patients with HER2 (ERBB2)-mutated disease follows an approval last August for use after prior systemic therapy.

News All Time

SNNOOP10 to Screen for Primary vs Secondary Headaches

Dr Nina Lum discusses the SNNOOP10 mnemonic for screening for primary vs secondary headaches.

Infographic: Foreign-Trained Docs Help With Shortage Here

Strong majorities of physicians in the US think doctors trained in other countries receive solid schooling and training and could help with shortages here.

Episode 3: Primary Aldosteronism and Secondary Hypertension

Drs Marwah Abdalla and Vivek Bhalla discuss the screening, management, and future of primary aldosteronism -- a common cause of secondary hypertension.

Managing Chronic Hepatitis B: New Guideline Expands Options

Joint AASLD/IDSA practice recommendations reflect new data on prevention, treatment, and surveillance of chronic hepatitis B, emphasizing collaborative decision-making.

Treating Cancer by Molecular Footprint, Not Organ

Shifting the focus from organ to biomarker has unlocked new options for rare and advanced cancers. Uneven efficacy, diagnostic access, and regulation still slow clinical rollout.

Risk-Reducing Mastectomy in BRCA1/2: Does It Save Lives?

Two recent studies aim to clarify whether risk-reducing bilateral mastectomy among BRCA1/2 carriers can improve survival, but the findings underscore the limits of the current evidence.

Galleri Cancer Detection Test Fails in Key Trial: Now What?

Despite efforts by test maker Grail to highlight outcomes the company considers positive, some experts are warning against using the Galleri test and others like it.

New Deprescribing Guidance Marks ‘Important Moment’ in Psych

A new consensus statement from the American Society of Clinical Psychopharmacology offers guidance on when — and whether — to discontinue psychotropic medications.

CKD Linked to Higher Risk for Workforce Detachment

Chronic kidney disease is associated with a significantly increased risk for workforce detachment among adults of working age, a Danish study finds.

Residents With Children Are at a Financial Breaking Point

As childcare costs soar and pay lags behind inflation, residents are forced into impossible choices about family and training.

Maternity Services ‘Still Failing’ Women and Babies

An interim review finds discrimination, staffing gaps, and poor facilities continue to undermine NHS maternity care in England.

Hospitals Face Measles Challenge: Few Doctors Have Seen It

As the US hospitals face an increasing risk of encountering measles, healthcare workers face an unusual barrier: Many don’t know what it looks like.

Blood Test Predicts Timing of Alzheimer’s Onset

Plasma p-tau217 levels predict the timing of Alzheimer’s onset in cognitively unimpaired adults in the research that could potentially guide research and preventive trials.

Higher Genetic Risk for IBD Linked to Disease Severity

Higher genetic risk for inflammatory bowel disease is linked to more severe disease and increased risks for hospital stays and earlier need for advanced treatments.

MDMA Analogue Shows Rapid, Durable Benefit in PTSD

A novel, non-hallucinogenic, experimental drug shows statistically significant, rapid, and durable improvement in PTSD symptom severity in a phase 2 trial.

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