Paxlovid does not increase risk of COVID reinfection: study

Published Date: 16 Feb 2023

Although there are concerns that the use of Paxlovid increases the risk of COVID-19 returning, the results are clear.

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Proteinuria Remission Predicts Outcomes in Pediatric IgAN

Children with IgA nephropathy who achieve sustained proteinuria remission have significantly better long-term kidney function over 5 years than those who do not.

Digital Pillbox Boosts Short-Term Viral Control in Young PWH

A digital pillbox with medication reminders and adherence feedback improves viral suppression in young people with HIV over 6 months, a trial finds.

Ketamine Infusions Shows Benefit in Bipolar Depression

Adjunctive serial IV ketamine infusions significantly reduced depressive symptoms in TRBD, with no cases of mania, hypomania, or psychosis observed in the randomized trial.

Once-Nightly Eye Drop Aids Dim-Light Vision

In patients who face difficulty seeing in low light, a once-nightly eye drop significantly improves night vision and reduces glare, halos, and starbursts, a phase 3 trial shows.

BRCA Mutation Carriers Likely to Have Risk-Reducing Surgery

Researchers conduct a study of about 4000 women with pathogenic variants in at least one of 13 breast cancer susceptibility genes to see their utilization of cancer risk-reducing procedures.

Distinct Risk Factor Profiles Tied to Endometriosis Subtypes

Various factors such as menstrual history, pain conditions, and immune disorders are distinctly tied to endometriosis lesion types — superficial lesions, ovarian cysts, and deep lesions.

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FDA Approves Camizestrant for ESR1-Mutated Breast Cancer

The accelerated approval enables an endocrine therapy switch when the ESR1 resistance mutation is detected, rather than waiting for evidence of disease progression.

Todays Updates

FDA Approves Camizestrant for ESR1-Mutated Breast Cancer

The accelerated approval enables an endocrine therapy switch when the ESR1 resistance mutation is detected, rather than waiting for evidence of disease progression.

Latest News

Children with IgA nephropathy who achieve sustained proteinuria remission have significantly better long-term kidney function over 5 years than those who do not.

A digital pillbox with medication reminders and adherence feedback improves viral suppression in young people with HIV over 6 months, a trial finds.

Adjunctive serial IV ketamine infusions significantly reduced depressive symptoms in TRBD, with no cases of mania, hypomania, or psychosis observed in the randomized trial.

In patients who face difficulty seeing in low light, a once-nightly eye drop significantly improves night vision and reduces glare, halos, and starbursts, a phase 3 trial shows.

Researchers conduct a study of about 4000 women with pathogenic variants in at least one of 13 breast cancer susceptibility genes to see their utilization of cancer risk-reducing procedures.

Various factors such as menstrual history, pain conditions, and immune disorders are distinctly tied to endometriosis lesion types — superficial lesions, ovarian cysts, and deep lesions.

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Establishing a CWO at a VAMC to Improve Clinician Well-Being

A Chief Well-Being Officer can improve organizational health and clinician quality of life, and multiple VHA facilities have developed the position at their institutions.

Medical Societies Join Forces to Restore Trust in Vaccines

The AMA, the Vaccine Integrity Project, and four specialty societies have joined forces to deliver evidence-based recommendations for the 2026-2027 respiratory virus season.

Serious Neutropenia in Clozapine Use: Rare, Occurs Early

Serious neutropenia requiring clozapine cessation is rare, occurs within the first 15 weeks of treatment, and is predicted strongly by older age and a low WBC count.

Another Severe Chemo Shortage: Why Is the US So Vulnerable?

A critical ifosfamide shortage is forcing cancer centers to ration a decades-old chemotherapy, once again highlighting structural weaknesses in the US market for essential generic drugs.

Belgian Physician Hans Kluge Enters Race to Lead WHO

Belgium has put Hans Kluge forward as the WHO’s top post, setting up a leadership contest that will shape global health priorities after Tedros’s final term ends in 2027.

Frailty Score Can Predict Mortality in Dialysis Patients

A simple bedside frailty rating by nurses can help predict mortality among patients undergoing dialysis, supporting its practical role as a complementary tool for risk assessment in routine care.

Survey Finds Patients Withhold Symptoms

Women and younger adults are more likely to hold back during medical visits, according to a German survey of 1791 adults.

Higher Resilience Tied to Lower End-of-Life Symptom Burden

Higher psychological resilience, assessed years before death, is linked to lower rates of depression, fatigue, pain, and incontinence at the end of life.

Antiseizure Drugs in Pregnancy Linked to Poor Fetal Growth

Infants exposed prenatally to antiseizure medication, particularly polytherapy and certain monotherapies, have higher risk for reduced birth weight and small for gestational age.

How No Burp Syndrome Went From Mystery to Diagnosis

Internet forums have exposed this painful condition marked by a previously unrecognized symptom: the inability to belch.

Low B12, Folate in Fathers Linked to Birth Defects

Nutrient deficiencies among both parents during conception and early pregnancy were associated with a greater risk for birth defects in a new study.

Shorter RT Schedule Linked to Worse Glioblastoma Survival

New research finds a 2-week ultrahypofractionated radiation regimen is associated with shorter overall survival and more radiation necrosis than standard 6-week chemoradiation.

FDA Psychiatry Digest: August 2026

A monthly snapshot of FDA activity involving therapies used in the prevention, diagnosis, and treatment of psychiatric conditions.

OnabotulinumtoxinA Effective in Hard-to-Treat Migraine

OnabotulinumtoxinA reduces headache days and resolves medication overuse in patients with chronic migraine and multiple prior preventive treatment failures.

Depression May Mask Early Cognitive Decline

Depression and early dementia can look alike in primary care, and experts say longitudinal cognitive monitoring is key to telling them apart.

Sharp Rise in Children Attending A&E in Mental Health Crisis

New analysis reveals a steep rise in children attending A&E in England with mental health concerns.

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