Paxlovid does not increase risk of COVID reinfection: study

Published Date: 16 Feb 2023

Although there are concerns that the use of Paxlovid increases the risk of COVID-19 returning, the results are clear.

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Diagnosing Alpha-Gal Syndrome in Children

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

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Todays Updates

FDA Declines to Approve Achieve Life Sciences' Smoking-cessation Drug

The U.S. Food and Drug Administration has declined to approve Achieve Life Sciences' drug to treat nicotine dependence in adults, ⁠citing unresolved issues found at a...

The New Perfectionism Problem in Medical Training

The profession has always attracted perfectionists. Experts worry a more fear-based version of the trait could affect both doctors and patients.

Rucaparib Delays Next Lines of Therapy in Ovarian Cancer

Rucaparib maintenance delays both first and second subsequent therapies among patients with advanced ovarian cancer.

Latest News

Less than 1% of patients with primary aldosteronism are diagnosed. The Curbsiders are here to help change that with practical screening and treatment tips.

Dr. Hodge emphasizes that carefully taking a history is the first step toward diagnosing this relatively rare syndrome in children.

Social anxiety disorder is now one of the most common mental health challenges in Canada, with a 71% increase in prevalence since 2002.

Former cigarette smokers who switch to noncombustible nicotine or tobacco products have a higher risk for major vision-impairing eye diseases than those who quit tobacco and nicotine entirely.

A proof-of-concept study suggests the 5-HT4 receptor agonist prucalopride, which is approved for chronic constipation, improves cognition in patients with remitted depression.

Clinicians are urging GPs to treat gambling harm with the same routine scrutiny as alcohol and tobacco misuse, as World Cup gambling activity peaks.

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Can Chemoradiation Improve Outcomes in Pancreatic Cancer?

New data suggest adding chemoradiotherapy to adjuvant gemcitabine does not improve overall survival after pancreatic cancer resection, but one subgroup appears to benefit.

Monoclonal Antibodies May Complicate Transfusion Testing

Monoclonal antibody-based therapies can affect the results of transfusion tests, potentially leading to dangerous misinterpretations of the findings.

Does High-Dose Omega-3 Benefit Cognition in Older Adults?

High-dose omega-3 supplements reach the brain but offer no cognitive benefits in older adults at high-risk for Alzheimer’s disease, a new trial suggests.

Pneumococcal Vaccine Extended to High-Risk Children, Teens

FDA approves expanded indication for individuals aged 2-17 years with chronic medical conditions.

FDA Delays iPLEDGE Modifications Until November 2026

FDA Delays iPLEDGE modification implementation until November 15, 2026, to allow additional time to test system updates, minimize technical glitches.

AI Predicts Abiraterone Benefit in High-Risk Prostate Cancer

A multimodal AI model identified a subset of men with very high-risk localized prostate cancer who derived substantial benefit from adding abiraterone to standard therapy.

AI in Gastroenterology: Benefits, Risks, and Safeguards

In gastroenterology, LLMs can draft notes, summarize data, and assist with patient messaging but can also err, introduce bias, or compromise privacy.

Clinicians Get New Rules for Prescribing Weight-Loss Drugs

The guidance still centers on lifestyle changes but recognizes the progress made in pharmacologic treatments for overweight and obesity.

What Space Travel Teaches Us About Cancer Biology

Could low-orbit microgravity accelerate cancer research on Earth? Prof David Kerr unpacks a Lancet Oncology study on the ISS as a cancer biology platform.

AI's Prescription for Moral Injury

George Lundberg, MD, asked an LLM how to cope with the profound moral distress of our era. The algorithm’s surprisingly grounding advice might help you, too.

Why Readiness Is Not a Prerequisite for Lifestyle Change

Dr Padmaja Patel challenges the idea that lifestyle interventions only work for motivated patients, offering tips on how motivation can be built in the clinical setting.

ASM Levels Equivalent in Maternal and Cord Blood

Antiseizure medication levels in maternal and cord blood at delivery are similar in pregnant women with epilepsy, indicating significant placental passage, a study shows.

Frequent Migraines? Hold the Toothpaste

Switching from toothpaste to saline for brushing teeth was associated with significant reductions in migraine frequency and severity, a new short-term study suggests.

Expanded Diagnostic Criteria Behind ADHD, Autism Rise?

Genetic data suggest that expanding diagnostic criteria may account for much of the increase in ADHD and autism diagnoses.

Blinatumomab Outperforms Chemotherapy in High-Risk B-ALL

Children receiving blinatumomab instead of two chemotherapy blocks have higher event-free survival and fewer relapses.

Poor Sleep in Midlife Tied to Worse Well-Being Years Later

Sleep problems in midlife may cast a long shadow on psychological well-being, with women showing greater vulnerability than men nearly a decade later.

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