The Sweetener Trap: Are Sugar Alternatives Backfiring?

Published Date: 23 May 2026

Emerging evidence suggests some sugar substitutes may affect metabolism, gut microbiome, and cardiovascular health more than previously recognized.

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Latest News

Novo Nordisk Says Wegovy Approved in China for MASH

Denmark's Novo Nordisk ⁠said on Thursday its blockbuster ⁠weight-loss drug Wegovy had ⁠been approved ‌in China as the first GLP-1 RA class of drugs for the ‌treatment of MASH.

Obesity Rises Faster in Young Adults, Steeper in Older Adults

Obesity is increasing faster among young adults worldwide, even as older adults still carry the greater overall burden, a new analysis of 196 countries over three decades finds.

Diabetes Care in Danish Care Homes May Miss the Mark

About 1 in 8 Danish care home residents with T2D admitted from 2018 to 2023 used glucose-lowering drugs, and most continued treatment despite having A1c levels below recommended targets.

High Semaglutide Dropout Rates Signal Adherence Challenge

With nearly half of patients discontinuing semaglutide within 12 months — especially younger adults — clinicians face a growing challenge in sustaining long-term treatment.

Menopausal Symptoms Worse in Women With Type 2 Diabetes

An observational study finds a higher number of symptoms and greater severity among midlife women with type 2 diabetes than among those without.

Weekly Basal Insulin + Semaglutide Combo May Benefit T2D

Novo Nordisk’s phase 3b trial shows once-weekly IcoSema improves glycemic control and weight with less hypoglycemia than insulin glargine U100 in adults with type 2 diabetes.

Todays Updates

UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

Tissue-Free ctDNA Predicts Recurrence in Early Breast Cancer

Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

Can Response-Adapted Surgery Improve Outcomes in HNSCC?

Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

TKI Discontinuation Feasible After ALL Treatment

In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

SBRT Plus Atezolizumab Shows No Benefit in Inoperable NSCLC

For patients with early-stage, inoperable lung cancer, adding atezolizumab to standard radiotherapy boosts toxicity, not survival.

Todays Updates

UK Lawmakers Reject Bid to Legalise Assisted Dying

British lawmakers rejected on Friday a proposal to legalise assisted dying for terminally ill people, dealing a major setback to campaigners and bringing the latest effort...

Liberalized Cannabis Policies May Increase Substance Use

In a global review, legalization was associated with increased cannabis use and related emergency department visits, with potential decreases in the use of alcohol and tobacco.

Tissue-Free ctDNA Predicts Recurrence in Early Breast Cancer

Researchers analyzed plasma samples collected from 313 patients with early breast cancer approximately 2 years after they had completed adjuvant chemotherapy.

Can Response-Adapted Surgery Improve Outcomes in HNSCC?

Patients who respond to neoadjuvant immunochemotherapy may be able to undergo less extensive surgery, with high rates of disease control and organ preservation.

TKI Discontinuation Feasible After ALL Treatment

In patients with first- or second-line Philadelphia-positive B-cell acute lymphoblastic leukemia, favorable outcomes are observed with discontinuation of ponatinib.

SBRT Plus Atezolizumab Shows No Benefit in Inoperable NSCLC

For patients with early-stage, inoperable lung cancer, adding atezolizumab to standard radiotherapy boosts toxicity, not survival.

Latest News

Denmark's Novo Nordisk ⁠said on Thursday its blockbuster ⁠weight-loss drug Wegovy had ⁠been approved ‌in China as the first GLP-1 RA class of drugs for the ‌treatment of MASH.

Obesity is increasing faster among young adults worldwide, even as older adults still carry the greater overall burden, a new analysis of 196 countries over three decades finds.

About 1 in 8 Danish care home residents with T2D admitted from 2018 to 2023 used glucose-lowering drugs, and most continued treatment despite having A1c levels below recommended targets.

With nearly half of patients discontinuing semaglutide within 12 months — especially younger adults — clinicians face a growing challenge in sustaining long-term treatment.

An observational study finds a higher number of symptoms and greater severity among midlife women with type 2 diabetes than among those without.

Novo Nordisk’s phase 3b trial shows once-weekly IcoSema improves glycemic control and weight with less hypoglycemia than insulin glargine U100 in adults with type 2 diabetes.

News All Time

How to Help Manage Depression After GLP-1 Weight Regain

Offer realistic expectations when medication use ends and provide the tools to remain on track.

Indian Activists Lodge Concerns About Food Warning Proposal

Activists spearheading calls for food labelling said a government proposal to have red warnings only when two concerning nutrients are high created ⁠an "industry-friendly loophole".

EMA Probes Injectable Iron Medicines for Bone Risks

European regulators launched a safety review of injectable iron medicines following reports of severe hypophosphatemia and osteomalacia.

US FDA Is Working With Manufacturers to Boost Estrogen Patch Supply Amid Access Concerns

The U.S. health regulator said on Thursday it is working with all six manufacturers to increase the supply of estradiol transdermal patches, ⁠used to treat menopause...

Medicare A1c Coverage Boosts Prediabetes Detection

Since Medicare began covering A1c for diabetes screening in 2024, use of the test and detection of prediabetes have risen dramatically among older adults.

GLP-1 Meds Linked to Symptomatic Remission in UC

GLP-1 receptor agonist therapy is linked to higher symptomatic remission rates among patients with ulcerative colitis, with benefits appearing independent of weight loss.

Keto Diet Outperforms Others in Liver Health in Obesity

Liver health improves more on a very-low-carbohydrate ketogenic diet than on a Mediterranean or very-low-fat plant-forward diet.

US Pentagon Issues Clinical Guidelines on Troop Testosterone Screening to Start Immediately

The U.S. Pentagon issued detailed guidance on Wednesday for a new, mandatory testosterone deficiency screening policy ⁠for active-duty and reserve service members age 30 and...

From Hunger to Obesity: Developing World Faces Growing Threat to Child Health

Intan Permatasari's mother simply couldn't refuse her daughter's pleas for food. By the time she was 4, Intan had outgrown all the kindergarten uniforms and had to wear...

Earlier SGLT2 Use After AKI May Improve Outcomes

Earlier SGLT2 inhibitor use after dialysis-requiring AKI is linked to better kidney outcomes in patients with type 2 diabetes, with no increase in safety events.

New Tool Helps Clinicians Screen for Obesity’s Causes

Experts have developed a new 25-minute tool to screen patients for over 30 possible causes of obesity, from genetics to psychological trauma.

Too Weak, Too Strict: India's Food Warning Labels Draw Fire From All Sides

The Indian government is facing fierce opposition on proposed food warning labels from both health experts and food giants - activists say many items will escape scrutiny...

Early Childhood Obesity Linked to Adolescent Obesity Risk

Obesity during early childhood is strongly linked to obesity by adolescence, whereas overweight carries a far smaller risk for progression — even after a recent BMI rise from normal weight.

600,000 Seniors Have Signed Up for Obesity Drugs Under New Medicare Program

U.S. Centers for ⁠Medicare and Medicaid Services Administrator ⁠Dr. Mehmet Oz said ⁠on Monday ‌that 600,000 seniors have signed up to receive GLP-1 weight ‌loss medications...

Hims & Hers Offers GLP-1s, Men's Health Treatments in Australia

Telehealth company Hims & Hers has begun offering GLP-1 weight-loss drugs and other treatments ⁠to men in Australia as it continues to expand its international business.

Time-Restricted Eating Helps Sustain Weight Loss

New research shows an 8-hour eating window can help sustain weight loss for a year. Meal timing, alongside diet quality and exercise may be a useful, personalized tool.

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