STI Diagnoses Drop, but Syphilis in Women Rises

Published Date: 05 Jun 2026

England saw its sharpest fall in STI diagnoses in years in 2025, though syphilis trends in women are moving in the wrong direction.

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The Future of Oncology Clinical Pathways in VHA

VA oncology Clinical Pathways logged 26,613 entries for 11,835 patients in FY25, standardizing care and paving the way to Oracle Health EHR.

Normal, but Not Optimal: Rethinking Perimenopause

In this roundtable, Drs Rachel Rubin, Makeba Williams, and Anna Cabeca discuss the changing landscape of perimenopause care — and why every clinician should join the conversation.

Inflammation on Imaging May Help Predict Hand OA Progression

Synovitis detected using ultrasonography and MRI is associated with increased odds of structural worsening in thumb base and finger joints in patients with hand osteoarthritis.

Allo-HSCT Shows Long-Term Benefit in Hepatosplenic Lymphoma

Researchers examine the roles of allogeneic and autologous HSCT in patients with hepatosplenic T-cell lymphoma and identify factors linked to survival after transplantation.
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Cenobamate May Offer Benefits in Rare Childhood Epilepsy

Cenobamate is linked to sustained seizure control and higher treatment retention rates over 12 months in children with developmental and epileptic encephalopathies.

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Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

Todays Updates

Sevabertinib Approved for First-Line Mutated NSCLC

The oral HER2 TKI was previously given accelerated approval in the second line for the indication.

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In this roundtable, Drs Rachel Rubin, Makeba Williams, and Anna Cabeca discuss the changing landscape of perimenopause care — and why every clinician should join the conversation.

Synovitis detected using ultrasonography and MRI is associated with increased odds of structural worsening in thumb base and finger joints in patients with hand osteoarthritis.
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Insomnia diagnoses and related pharmacologic prescriptions show a rise among adults in Central Catalonia; those with insomnia and polypharmacy are more likely to receive pharmacologic treatment.

Cenobamate is linked to sustained seizure control and higher treatment retention rates over 12 months in children with developmental and epileptic encephalopathies.

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Digital Pillbox Boosts Short-Term Viral Control in Young PWH

A digital pillbox with medication reminders and adherence feedback improves viral suppression in young people with HIV over 6 months, a trial finds.

Ketamine Infusions Shows Benefit in Bipolar Depression

Adjunctive serial IV ketamine infusions significantly reduced depressive symptoms in TRBD, with no cases of mania, hypomania, or psychosis observed in the randomized trial.
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BRCA Mutation Carriers Likely to Have Risk-Reducing Surgery

Researchers conduct a study of about 4000 women with pathogenic variants in at least one of 13 breast cancer susceptibility genes to see their utilization of cancer risk-reducing procedures.

Distinct Risk Factor Profiles Tied to Endometriosis Subtypes

Various factors such as menstrual history, pain conditions, and immune disorders are distinctly tied to endometriosis lesion types — superficial lesions, ovarian cysts, and deep lesions.
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A Public Utility Model for Primary Care?

As more struggling practices turn to private equity, Dr Kenny Lin asks who benefits — and whether a public utility model offers a workable alternative.
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Greater Depression Severity Predicts Higher iCBT Benefits

An individual treatment benefit prediction model reveals that patients with more severe depression receive greater benefits from internet-based cognitive-behavioural therapy.
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Does Liver Disease Affect Cholangiocarcinoma Outcomes?

Patients diagnosed with cholangiocarcinoma who have preexisting chronic liver disease experience improved survival compared with those who do not have prior chronic liver disease.
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