Lipid-Lowering Med Advances to Alzheimer’s Prevention Trial

Published Date: 24 Jul 2026

The lipid-lowering drug obicetrapib produces the greatest reductions in the Alzheimer’s biomarker p-tau217 among APOE4 carriers, providing the rationale for a planned Alzheimer’s prevention trial.

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Patients with obstructive sleep apnea who live in disadvantaged neighborhoods experience more severe sleep-related hypoxemia and have a higher risk for cardiovascular events.

CGM and A1c increasingly disagree, especially with AID pumps. When should clinicians trust time in range over A1c? The evidence, the guideline gaps, and access disparities in type 1 and 2 diabetes.

The magnitude of the risk varies widely by cancer type, being highest for patients with lung or pancreatic cancers.

Elevated markers of liver fat, fibrosis, and functional decline are associated with an increased risk for cardiovascular disease in people without clinical liver disease at baseline.

Functional angiography is linked to a 38% lower risk for the primary outcome over conventional angiography in STEMI patients with multivessel disease.

Large cohort study shows sweet spot at 1-3 g/dL above the WHO threshold.

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