Lipid-Lowering Med Advances to Alzheimer’s Prevention Trial

Published Date: 24 Jul 2026

The lipid-lowering drug obicetrapib produces the greatest reductions in the Alzheimer’s biomarker p-tau217 among APOE4 carriers, providing the rationale for a planned Alzheimer’s prevention trial.

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Latest News

Customizable polypill for patients with heart failure with reduced ejection fraction may improve adherence and lower pill burden, and its use appears feasible and acceptable.

What patients ‘think’ is important about muscle isn’t usually what will benefit them most — especially if they’re hesitant to strength train.

Extreme heat, humidity, altitude, and travel-related disruptions may challenge 2026 World Cup players’ endurance, recovery, and overall performance.

Life expectancy at age 50 years has increased in US individuals with a history of stroke.

In an observational study, statin use was associated with slower cognitive decline in women with Alzheimer’s disease and elevated low-density lipoprotein cholesterol.

Two experts debated this question at the American Diabetes Association 2026 Scientific Sessions.

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MHRA Contraindicates Domperidone in Phaeochromocytoma

A European safety review found four reports of severe hypertension linked to domperidone in these patients.

Home ECG Alerts Often Do Not Prompt Follow-up for AF

Older adults with hypertension who received atrial fibrillation alerts from home blood pressure monitors rarely sought medical evaluation, and nearly half with confirmed AF remained undiagnosed a year later.

Hypertension in HCM: What Clinicians Should Know

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Thyroid Issues Can Worsen Prognosis of Heart Failure

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Penile Enlargement Surgery: Can Size Improvements Last?

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Tenecteplase Speeds Acute Ischemic Stroke Care

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Adults Aged 75 or Older With MASLD Face Polypharmacy Burden

Among older adults with metabolic dysfunction-associated steatotic liver disease, those aged 75 years or older face a notable burden of polypharmacy.

AI Tool Flags Six Acute Abdominal Emergencies on CT

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5 Smarter Ways to Beat Medical Information Overload

Medical evidence continues to grow rapidly, and these five practical strategies help physicians prioritize high-quality research, use AI effectively, and stay current more efficiently.

Grumblings Over CKM Guideline Not Warranted, Experts Say

Experts push back against concerns of overmedicalization and confusing staging with the new AHA/ACC guideline on cardiovascular-kidney-metabolic syndrome.

Eleven New Molecular Targets Expand Treatment Options

Eleven new molecular drug targets receive approval in 2025, expanding treatment options for rare diseases, cancer, and infectious diseases.

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From pretravel counseling to vaccinations, prophylaxis, and environmental precautions, here is how general practitioners can help travelers reduce risks before and during their trip.

Can Europe Keep Its Medicines Cool in 40 °C+ Summers?

As European heat waves shatter records, aging clinical infrastructure and lack of funding leave lifesaving, temperature-sensitive drugs vulnerable to degradation.

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A genome-wide association study links genetic variants to reduced coronary flow reserve, implicating the nuclear factor kappa B pathway in coronary microvascular disease.

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