Psilocybin reduces symptoms of major depression: The Lancet

Published Date: 04 Mar 2023

A new study by Robin von Rotz and his team found that moderate doses of psilocybin for at least two weeks reduced symptoms of depression...

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Retaining APPs: Why One APP Won’t Leave Rheumatology

Clear expectations, mutual respect with physicians, and compensation models all play important roles in retaining advanced practice providers, a physician assistant says.

Pneumonia Tied to Noncommunicable Disease Risk in Adults

Hospitalization for community-acquired pneumonia is linked to an increased risk of developing multiple chronic noncommunicable diseases over 5 years in adults.

Is ‘Spring Fatigue’ Real? Sleep Study Questions It

In a nine-wave online survey of 418 adults over 18 months, researchers find fatigue levels do not fluctuate seasonally — only everyday activity fatigue falls as days lengthen.

Telemedicine Matches Clinic Visits in IIH Care

Remote consults using optical coherence tomography data show high agreement with traditional clinic evaluations for the management of patients with idiopathic intracranial hypertension.

When Medications May Contribute to Cognitive Decline

Medication-related cognitive impairment is common, mimics neurodegenerative disease, increases with polypharmacy, and may be prevented with regular cognitive assessment monitoring.

Access to Mental Health Support ‘Uneven’ for Young Canadians

The need for mental health support services is high in Canada, especially among youth, but many are unable to access the care they need in a timely manner.

Todays Updates

Insulin Resistance Detected Early May Guide HS Therapy

Screening for insulin resistance early after the diagnosis of hidradenitis suppurativa shows promise for guiding therapies to improve the disease course.

Dermatomyositis: Targeted Drug Shows Promise vs Placebo

At 52 weeks, the 30-mg daily oral dose of brepocitinib outperformed the 15-mg dose in a study of patients with dermatomyositis resistant to previous treatments.

Melasma: A New Era of Topical Treatment Options Galore

Combination therapies remain key as multiple agents for melasma hit the market.

LAAC an Alternative for NOAC in Lower-Risk AF Patients

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Fibrinolytic Beats Current Standard for Intermediate-Risk PE

For intermediate-risk pulmonary embolism, a low-dose fibrinolysis strategy reduced PE-related events by half with no significant increase in bleeding vs standard therapy.

PCKS9 Inhibitors Seen Driving Down LDL-C in Diabetes

A subgroup analysis of the VESALIUS-CV trial showed evolocumab significantly cut LDL cholesterol and cardiovascular event risk in people with diabetes but no known atherosclerosis.

High Dx Yield Supports Workup for INOCA

Performed with favorable safety, the diagnostic yield for coronary function testing in patients with ischemia but nonobstructive arteries was found to exceed 90%.

Todays Updates

Insulin Resistance Detected Early May Guide HS Therapy

Screening for insulin resistance early after the diagnosis of hidradenitis suppurativa shows promise for guiding therapies to improve the disease course.

Dermatomyositis: Targeted Drug Shows Promise vs Placebo

At 52 weeks, the 30-mg daily oral dose of brepocitinib outperformed the 15-mg dose in a study of patients with dermatomyositis resistant to previous treatments.

Melasma: A New Era of Topical Treatment Options Galore

Combination therapies remain key as multiple agents for melasma hit the market.

LAAC an Alternative for NOAC in Lower-Risk AF Patients

CHAMPION-AF finds left atrial appendage closure and anticoagulation therapy for atrial fibrillation about equal but raises doubts about whether the former is a true alternative.

Fibrinolytic Beats Current Standard for Intermediate-Risk PE

For intermediate-risk pulmonary embolism, a low-dose fibrinolysis strategy reduced PE-related events by half with no significant increase in bleeding vs standard therapy.

PCKS9 Inhibitors Seen Driving Down LDL-C in Diabetes

A subgroup analysis of the VESALIUS-CV trial showed evolocumab significantly cut LDL cholesterol and cardiovascular event risk in people with diabetes but no known atherosclerosis.

High Dx Yield Supports Workup for INOCA

Performed with favorable safety, the diagnostic yield for coronary function testing in patients with ischemia but nonobstructive arteries was found to exceed 90%.

Latest News

Clear expectations, mutual respect with physicians, and compensation models all play important roles in retaining advanced practice providers, a physician assistant says.

Hospitalization for community-acquired pneumonia is linked to an increased risk of developing multiple chronic noncommunicable diseases over 5 years in adults.

In a nine-wave online survey of 418 adults over 18 months, researchers find fatigue levels do not fluctuate seasonally — only everyday activity fatigue falls as days lengthen.

Remote consults using optical coherence tomography data show high agreement with traditional clinic evaluations for the management of patients with idiopathic intracranial hypertension.

Medication-related cognitive impairment is common, mimics neurodegenerative disease, increases with polypharmacy, and may be prevented with regular cognitive assessment monitoring.

The need for mental health support services is high in Canada, especially among youth, but many are unable to access the care they need in a timely manner.

News All Time

AHS Recommends Annual Migraine Screening for Girls and Women

A new recommendation from the American Headache Society calls for annual migraine screening as part of preventive care for girls and women — from adolescence through menopause.

Biologics Don’t Promote Respiratory Infections

Reassuring data support the safety of biologics as an option for asthma care.

Biologics, Phototherapy in Psoriasis: Cost-Benefit Compared

A simulated analysis in psoriasis highlights divergent patient and payer incentives and inconsistent coverage strategies behind barriers to phototherapy uptake.

Spirituality Linked to Lower Risk for Substance Misuse

Integrating spirituality into patient care might hold potential for substance use prevention and recovery, a new meta-analysis shows.

GSK Gets US FDA Approval for Expanded Use Of RSV Vaccine

British drugmaker GSK said on Friday the U.S. Food and Drug ⁠Administration has expanded the approved age range for its respiratory syncytial virus vaccine, ⁠Arexvy, to...

WHO Confirms 18 Attacks on Healthcare Sites in Iran

The World Health Organization said on Wednesday that it has verified 18 attacks on healthcare centers ⁠in Iran since the start of the U.S. and Israel war on Iran.

How Can First-Year Residents Avoid Clinical Errors?

Experts say that many early residency mistakes stem from structural factors such as workload, supervision, and training environment, rather than from individual performance.

Dry Powder Inhaler May Reduce COPD Exacerbations

In patients with COPD, starting the umeclidinium-vilanterol dry powder inhaler may lower the risk for exacerbations compared with starting glycopyrrolate-formoterol or tiotropium-olodaterol inhalers.

Add-On Vancomycin Taper May Reduce C difficile Recurrence

In patients with a first episode or first recurrence of Clostridioides difficile infection, adding a vancomycin taper after the standard 14-day course may delay or lower the risk for recurrence.

Donna Ockenden to Lead Review of Leeds Maternity Failures

An independent review will examine maternity and neonatal services at Leeds Teaching Hospitals after repeated safety failures.

Tylenol Use Among Women Dropped After Trump Tied It to Autism, Lancet Analysis Shows

Tylenol use among pregnant women fell after U.S. President Donald Trump linked autism to the over-the-counter pain relief medicine, according to an analysis of U.S....

Generic Flovent Approval Expands Options for Asthma

Glenmark Specialty SA has received the FDA’s approval for true generic fluticasone propionate.

ETI Shows Minimal Bone Health Impact in Cystic Fibrosis

Elexacaftor-tezacaftor-ivacaftor combination therapy shows no clinically meaningful improvement in bone health or calcium metabolism in patients with cystic fibrosis, a Danish study shows.

Hospitalists Get Creative to Find Time for Research

Sometimes that may mean carving out an hour here or there during the day and, sometimes, it may mean working on a day off.

Rethinking Osteoarthritis: Inflammation, Metabolism, Repair

Emerging regenerative and cell-based therapies promise cartilage repair, yet most are preclinical or limited by durability and safety — underscoring the need for rigorous stratification.

Jamaica to End Medical Cooperation Program With Cuba

Jamaica will end a medical cooperation program with Cuba, ⁠as the two governments were unable to agree on the terms ⁠for a new arrangement.

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