Ketamine IV for the prevention of depression in the elderly: new data

Published Date: 13 Mar 2023

Intravenous (IV) ketamine is effective in adults resistant to depression. The response was similar to that seen in younger patients, two new studies show.

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A&E Waits Hit Over-80s Hardest, Analysis Shows

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ED-Discharged Current Smokers Open to Cessation Support

Most current smokers discharged from the emergency department who are reached by automated calls express interest in quitting smoking, but only about 1 in 5 accept a Quitline referral, a study finds.

Endometriosis Linked to More Severe PID

Women with endometriosis hospitalized for pelvic inflammatory disease faced higher risk of treatment failure and disease recurrence than those without endometriosis.

Health Rounds: MannKind Injection Helps Heart Failure Patients Avoid ER Infusions

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays)

Todays Updates

Defibrotide Prophylaxis May Reduce SOS Risk After HSCT

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Todays Updates

Defibrotide Prophylaxis May Reduce SOS Risk After HSCT

A study evaluates whether defibrotide prophylaxis during HSCT reduces the risk for sinusoidal obstruction syndrome in children with relapsed or refractory B-ALL receiving prior inotuzumab.

Latest News

The U.S. FDA on Wednesday approved the first freeze-dried plasma product for use in the country, providing an ⁠option for patients when conventional plasma is...

GMC data show fitness to practise concerns rose 25% in 2025, though 90% failed to meet the threshold for a full investigation.

New Nuffield Trust analysis finds over-80s in England are more than twice as likely as younger patients to face 12-hour A&E waits.

Most current smokers discharged from the emergency department who are reached by automated calls express interest in quitting smoking, but only about 1 in 5 accept a Quitline referral, a study finds.

Women with endometriosis hospitalized for pelvic inflammatory disease faced higher risk of treatment failure and disease recurrence than those without endometriosis.

(This is an excerpt of the Health Rounds newsletter, where we present latest medical studies on Tuesdays and Thursdays)

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Algorithm Rules Out Pulmonary Embolism in Cancer Patients

A clinical trial finds that an algorithm routinely used to rule out pulmonary embolism works in patients with cancer, too — and could avoid up to 80,000 CT scans per year in the US.

Emergency Department Noise Levels Exceed Safety Thresholds

Emergency department noise levels consistently exceed recommended safety thresholds and coincide with more communication-related safety events, a study finds.

AKA Underdiagnosed in Alcohol-Related ED Visits

More than 1 in 10 patients with alcohol-related emergency visits have alcoholic ketoacidosis, a study finds, highlighting that the condition is often underdiagnosed.

Public Wary of AI Scribes for Sensitive Consultations

A Healthwatch England poll finds most people want explicit consent and human oversight when AI scribes are used in NHS appointments.

Heat Exposure Tied to AD Biomarker Changes in Women

Long-term exposure to outdoor heat was associated with lower amyloid-beta42/40 and higher p-tau181 levels in older women, but not men, suggesting heat may influence early AD-related pathology.

Ingestion of Multiple Drugs Common in Self-Poisoning

Nearly half of the patients presenting to the emergency department for intentional self-poisoning previously ingested multiple medications, majorly central nervous system drugs, a study finds.

Soccer-Masked World Cup Players Spotlight Soccer's Overlooked Facial Injury Risk

When soccer players collide in midair, the toll is not always counted in concussions, torn ligaments or twisted ankles.

ED Palliative Care Consultations Surge in Cancer Care

Emergency department-initiated hospice and palliative care consultations for patients with cancer surged from 2016 to 2023, particularly after the onset of the COVID-19 pandemic, a study finds.

Former Elite Soccer Players Show Altered Brain Health

Former elite soccer players show lower gray matter volume on MRI and report more depression, anxiety, and executive dysfunction than controls, despite similar performance on objective cognitive tests.

Buprenorphine XR Injections Cut 'Need-Based' Opioid Craving

Extended-release buprenorphine injections increase the number of opioid-free days primarily via direct pathways and by suppressing need-related craving, a causal mediation analysis shows.

DEA Targets Synthetic 7-OH Products With Schedule I Proposal

The DEA’s proposal would classify concentrated synthetic 7-OH products as Schedule I drugs, while leaving most botanical kratom outside the ban.

Which Factors Are Driving Older Canadians to the ED?

In Canada, ED overcrowding, particularly with older adults, is a healthcare system failure that must be addressed across disciplines, and with government support, experts say.

Most Childhood Headaches Remain Unclassified in Primary Care

Most cases of headache among children and adolescents in primary care remain unclassified, and many are prescribed acute medication.

Elderly Woman Survives Deadly Injury

The penetrating wound occurred doing pool maintenance

From Syria to Deliberate Pyridostigmine Overdose

Keeping one tragedy from begetting another

Ovarian Cancer Frequently Diagnosed Only After Hospital Admission

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