Epigenetics, predictive signals of satiety and obesity

Published Date: 02 Mar 2023

Researchers seek to predict markers of the state of obesity, the risk of associated complications and the response to diet or bariatric surgery.

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Adults with overweight or obesity receiving semaglutide eat significantly fewer calories than those on placebo through week 60, despite early gains in appetite control waning after week 20.

Those who use hormonal birth control, particularly those who switch methods multiple times, are far more likely to take semaglutide later in life.

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Adjunctive treatment with semaglutide or tirzepatide in patients with inflammatory bowel disease and obesity and/or diabetes may not reduce the risk for disease relapse.

A new review finds that pregnancy among trans men is real but still poorly studied, leaving clinicians without clear evidence-based guidance.

Researchers identify a new subphenotype of obesity marked by fast gastric emptying, low GLP-1 levels, and greater postmeal hunger that is tied to substantially greater weight loss with tirzepatide.

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