Epigenetics, predictive signals of satiety and obesity

Novo Nordisk Launches Higher-dose Wegovy in the United States

Novo Nordisk said on Tuesday that it has made ⁠a higher-dose version of its blockbuster weight-loss drug Wegovy ⁠available across the United States.

Weight Loss After Tirzepatide Varies by Prior Weight Change

Tirzepatide produced notable weight loss in real-world settings, but patients with prior weight loss experienced smaller additional reductions than those without.

Continuous Glucose Monitoring Expands in Type 2 Diabetes

Continuous glucose monitoring is expanding beyond type 1 diabetes, offering detailed glycemic insights that may support earlier intervention in patients with type 2 diabetes.

Can Oestrogen Patches Replace LHRH Agonists for Prostate Tx?

Transdermal oestradiol patches are non-inferior to luteinising hormone-releasing hormone agonists for metastasis free survival in locally advanced prostate cancer, a study shows.

Prior Bariatric Surgery Lowers Postop Risk Over GLP-1s

Another Pregnancy Can Worsen Insulin Sensitivity Over Time

In parous women, an additional pregnancy is linked to a selective decline in whole-body insulin sensitivity over 10 years, with no clear changes in beta-cell function or blood glucose levels.

Tirzepatide Effective Despite Weight-Inducing Meds

Tirzepatide is linked to significant weight loss in adults with overweight or obesity who are taking weight-inducing medications, suggesting benefits even when these therapies are continued.

US FDA Clarifies Policies on Compounding Of GLP-1 Medicines

The U.S. Food and Drug Administration on Wednesday clarified its policies on compounded versions of ⁠popular GLP-1 drugs, signaling tighter limits on their production as...

Analysis Links RAI Therapy to Breast Cancer Risk

Clinicians may want to discuss radioactive iodine therapy’s potential for increasing breast cancer risk with patients undergoing hyperthyroidism treatment, researchers say.

Immunovant's Treatment for Eye Disease Fails in Late-stage Trials

Immunovant said on Thursday that its therapy failed to reduce eye bulging ⁠when tested in patients with moderate-to-severe thyroid eye disease in two late-stage...

Sugary-Drink Taxes May Not Cut Fast-Food Beverage Calories

An analysis of Taco Bell drive-through sales data finds no overall reduction in the number of calories from beverages after the implementation of taxes on sugary drinks.

FDA Data Reveal Different Risks for GLP-1s

GLP-1s are linked to a broad range of adverse events — largely gastrointestinal, metabolic, and psychological — across indications, according to analysis of FDA reporting.

Sugar Tax Debate Intensifies as Health Evidence Builds

Evidence suggests that sugar taxes may influence obesity patterns among younger populations.

Airline Websites Vary on Info for Passengers With Obesity

Across 50 leading airlines globally, all offer some content for passengers with obesity, but the specifics vary widely.

Gene Therapy to Be Studied for Treating Type 1 Diabetes

A phase 1/2 trial of a novel viral vector gene therapy in adults with type 1 diabetes is scheduled to begin this year.

Viridian Eye Disease Drug Disappoints on Efficacy Despite Trial Success

Viridian Therapeutics' experimental treatment for thyroid eye ⁠disease lagged rivals in efficacy in a late-stage...