The white paper recommends extending endoscopic classification of gastroesophageal junction integrity beyond the slope.

Published Date: 08 Mar 2023

A new white paper from the American Foregut Society expands gastrointestinal tract (EGJ) classification, including axial hiatal hernia length, hiatal hernia opening diameter, ...

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Bone Pain in Paediatric IBD: A Rare but Important Link

In children with inflammatory bowel disease, persistent bone pain may signal chronic non-bacterial osteomyelitis, a rare association that commonly affects the lower limbs and pelvis.

Merck's Bowel Disease Drug Meets Main Goal in Late-stage Trial

Merck said on Monday its experimental drug met the main goal and key secondary goals ⁠in a late-stage trial in patients with a type of inflammatory bowel...

Common Anal Problems After Childbirth

Anal conditions affect up to 44% of women in labor yet remain underrecognized and poorly studied. Most cases improve with simple, conservative treatment.

China Approves CARsgen's CAR-T Treatment for Stomach Cancer

China's drug regulator said on Monday it has approved ⁠a CARsgen Therapeutics treatment for stomach cancer, a new milestone for CAR-T ⁠therapies, which engineer patients'...

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Cholera Death Toll in Northeast Nigeria Rises to 90, UN Says

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Todays Updates

Time to Rethink Maintenance Pemetrexed in NSCLC?

For patients with advanced non-small cell lung cancer (NSCLC), adding pemetrexed to maintenance pembrolizumab may only increase toxicity, not survival.

Todays Updates

Time to Rethink Maintenance Pemetrexed in NSCLC?

For patients with advanced non-small cell lung cancer (NSCLC), adding pemetrexed to maintenance pembrolizumab may only increase toxicity, not survival.

Latest News

In children with inflammatory bowel disease, persistent bone pain may signal chronic non-bacterial osteomyelitis, a rare association that commonly affects the lower limbs and pelvis.

Merck said on Monday its experimental drug met the main goal and key secondary goals ⁠in a late-stage trial in patients with a type of inflammatory bowel...

Anal conditions affect up to 44% of women in labor yet remain underrecognized and poorly studied. Most cases improve with simple, conservative treatment.

China's drug regulator said on Monday it has approved ⁠a CARsgen Therapeutics treatment for stomach cancer, a new milestone for CAR-T ⁠therapies, which engineer patients'...

Researchers conducted a population-based nested case-control study including individuals diagnosed with early-onset colorectal cancer and frequency-matched control individuals based on birth year.

At least ⁠90 people have died and more than 12,000 ⁠others have been infected in a fast-spreading ⁠cholera outbreak in ‌Nigeria's conflict-hit Borno state, the U.N. Office...

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Immunotherapy Plus TACE Improves PFS in Unresectable HCC

The study adds to growing evidence that immunotherapy and chemoembolization prolong progression-free survival.

Flesh-eating Screwworm Confirmed in Texas Calf as Parasite Crosses Border From Mexico

New World screwworm, a parasitic fly that eats warm-blooded animals alive, has been found in a calf in Texas, the U.S. Department of Agriculture said on Wednesday evening,...

Iza-Bren Beats Chemo in Second-Line Esophageal Cancer

In a phase 3 trial, izalontamab brengitecan shows superiority to chemotherapy in previously treated esophageal squamous cell carcinoma, but questions remain about generalizability outside China.

Antibiotic Effects on the Gut Detected Up to 8 Years Later

Changes in gut microbiome diversity are observed with certain antibiotic drugs years later, even after just one course of therapy.

Natural Supplements Linked to Cases of Severe Liver Injury

Experts warn that concentrated herbal and dietary supplements are increasingly linked to severe liver injury, while regulation remains limited.

Remote Monitoring in Cirrhosis Could Reduce Admissions

A digital monitoring system for advanced cirrhosis may help detect deterioration earlier and reduce hospital admissions.

Blood Test Added to US Colorectal Cancer Screening Options

People who skip colorectal cancer screening because colonoscopy or stool testing seems too burdensome now have a blood test option from Guardant Health among recommendations...

Can Intraperitoneal Paclitaxel Improve OS in Gastric Cancer?

A phase 3 trial explores whether adding intraperitoneal paclitaxel to intravenous paclitaxel plus S-1 improves overall survival in patients with gastric cancer and peritoneal metastasis.

Pancreatic Cancer Testing Falls Short of Goals

Researchers conducted a cross-sectional electronic survey to see whether respondents were offered and completed germline genetic testing following a pancreatic ductal adenocarcinoma diagnosis.

Pancreatic Cysts: What’s the Actual Cancer Risk?

Pancreatic cysts are common and usually considered low risk — but even those lesions signal a significantly elevated and sustained cancer risk.

UTI Treatment Shift: Is Nitrofurantoin Coming Out on Top?

A large Spanish trial reports higher cure rates with 5-day nitrofurantoin therapy than with fosfomycin or pivmecillinam in women with uncomplicated UTIs.

Takeda Engaged in Antitrust Scheme to Delay Generic Constipation Drug, US Jury Finds

A U.S. jury on Monday found Takeda Pharmaceutical liable for causing about $885 million in damages by delaying a generic version of its constipation drug Amitiza through an...

Blood Proteins Link Poor Sleep to Increased Cancer Risk

Suboptimal sleep health, reflected in low sleep proteomic scores, is consistently associated with an increased risk for cancer, particularly gastrointestinal malignancies.

Housing Instability Tied to Lower Rates of CRC Screening

Unmet health-related social needs, especially housing instability and transportation barriers, are linked to lower rates of screening for colorectal cancer among US adults.

Olanzapine Cuts Radiation-Induced Nausea

The drug, widely used for chemotherapy-related nausea, may also be highly effective for symptoms caused by abdominal-pelvic radiotherapy.

Barrett Esophagus Onset Occurs Decades Before Diagnosis

Molecular clock modeling suggests that the biological onset of Barrett esophagus occurs more than 20 years before the recommended screening age.

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