The white paper recommends extending endoscopic classification of gastroesophageal junction integrity beyond the slope.

Published Date: 08 Mar 2023

A new white paper from the American Foregut Society expands gastrointestinal tract (EGJ) classification, including axial hiatal hernia length, hiatal hernia opening diameter, ...

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Health Round: Experimental Blood Test Finds High-risk Colorectal Lesions Before Cancer Develops

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Constipation Relief: Elobixibat Outperforms Prucalopride

Elobixibat offers faster and greater symptomatic relief than prucalopride among patients with functional constipation unresponsive to first-line treatment.

Pancreatic Cysts: Sparing Use of Invasive Tests Seems Safe

Guidelines call for strict limits on invasive tests for pancreatic cyst surveillance, and a new study supports the strategy’s safety.

Patients’ Wait Times for Cancer Surgeries Keep Growing

Wait times for potentially curative cancer surgery, which have been climbing steadily for more than a decade, have risen particularly rapidly at high-volume academic centers.

Taylor Farms Outbreaks Show Limits Of US Ability to Safeguard Produce From Mexico

Two foodborne illness outbreaks linked to Taylor Farms have exposed a weakness at the heart of North America's food system: the United States is increasingly relying on...

US Health Agency Moves to Increase Oversight Of Food Additives

The U.S. Food and Drug Administration on Monday took steps to increase oversight of food additives as part ⁠of the Trump administration's "Make America Healthy Again"...

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Transgender Individuals Prefer HPV Self-Swabs

Transgender and gender-diverse individuals prefer self-collected HPV testing for cervical cancer screening, a new survey shows.

Todays Updates

NPM1-Mutated AML: Not All Treatments Are Equal

Researchers conducted a retrospective analysis of patients with newly diagnosed NPM1-mutated AML treated with high- or low-intensity regimens.

Transgender Individuals Prefer HPV Self-Swabs

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We also report on a flavoring chemical in e-cigarettes that damages human embryo cells in lab experiments.

Elobixibat offers faster and greater symptomatic relief than prucalopride among patients with functional constipation unresponsive to first-line treatment.

Guidelines call for strict limits on invasive tests for pancreatic cyst surveillance, and a new study supports the strategy’s safety.

Wait times for potentially curative cancer surgery, which have been climbing steadily for more than a decade, have risen particularly rapidly at high-volume academic centers.

Two foodborne illness outbreaks linked to Taylor Farms have exposed a weakness at the heart of North America's food system: the United States is increasingly relying on...

The U.S. Food and Drug Administration on Monday took steps to increase oversight of food additives as part ⁠of the Trump administration's "Make America Healthy Again"...

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US Cyclosporiasis Probe Linked to Lettuce Widens to 15 States

U.S. health authorities have widened their probe into a cyclosporiasis outbreak tied to iceberg lettuce from central Mexico after detecting cases in six additional states,...

Genetic Marker Linked to Severe Outcomes Across IBD Subtypes

HLA-DRB1*01:03 may serve as a genetic marker for severe outcomes across IBD phenotypes and help identify patients at higher risks for surgery and treatment failure.

Does High-Dose Vitamin D3 Supplementation Improve CRC Survival?

A phase 3 trial was conducted to confirm the benefit of high-dose vitamin D3 supplementation in patients with previously untreated metastatic CRC that was seen in a phase 2 trial.

IV Vitamin C With Chemo Shows Signals in Cancer Care

A phase 2 study reported a longer median overall survival in patients receiving IV ascorbate with chemotherapy, although larger randomized trials are needed to confirm the finding.

Small Colorectal Lesions Carry Risk for Deep Invasion

Non-pedunculated colorectal lesions smaller than 2 cm may harbor deep submucosal invasion despite their diminutive size, study finds.

Etrasimod Effective As First-Line Advanced UC Therapy

Etrasimod can be an effective and safe first-line advanced therapy option in patients with ulcerative colitis who escalate after conventional treatment failure.

Does Doublet Chemotherapy Improve Survival in Rectal Cancer?

Patients with high-risk locally advanced rectal cancer were randomly assigned to receive doublet-LC TNT or conventional neoadjuvant chemoradiotherapy.

Radiation Boost Linked to Better Survival in Rectal Cancer

A phase 2 trial finds that adding a modest radiation boost improves 9-year survival without increasing toxicity, despite no improvement in pathologic complete response.

Creatinine Assay Bias Affects MELD Scoring

Bilirubin interference in commonly used creatinine assays artificially inflates MELD scores in liver transplant candidates, a study reports.

EHR Marker May Help Curb Risk for Liver Transplant Rejection

A remote intervention aimed at improving medication adherence may reduce organ rejection in liver transplant recipients at high risk.

Altimmune Drug Cuts Heavy Drinking in Mid-stage Trial for Alcohol Use Disorder

Altimmune said on Tuesday its experimental drug helped patients with alcohol use disorder cut back on heavy drinking ⁠in a mid-stage trial, sending the company's shares 10%...

Newer Antibiotics Show No Clear Benefit for Staph Infections

A new meta-analysis finds ceftaroline and ceftobiprole monotherapy show no clear advantage over standard therapy for non-urinary Staphylococcus aureus infections.

FDA Approves Freenome's Blood Test for Colorectal Cancer Screening

The U.S. FDA has approved Freenome's blood-based colorectal cancer screening test for older adults, paving the way ⁠for partner Abbott to launch it in the U.S. this fall,...

Company At Center Of US Cyclospora Outbreak Complained to White House, Source Says

U.S. produce supplier Taylor Farms complained to White House and Food and Drug Administration officials about the government's inspection process earlier this month, a...

Poultry Firm Recalls Nearly 1.6 Million Dozen Eggs Over Salmonella Risk, FDA Says

The U.S. FDA said on Wednesday that Midwest Poultry Services is recalling nearly 1.6 ⁠million dozen eggs produced in Texas due to potential Salmonella...

CRC Screening in Adults Under 50: Research Reveals Trends

After colorectal cancer screening guidelines were updated in 2021 to lower the screening age to 45, three studies look at how providers are reaching those patients.

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