The white paper recommends extending endoscopic classification of gastroesophageal junction integrity beyond the slope.

Published Date: 08 Mar 2023

A new white paper from the American Foregut Society expands gastrointestinal tract (EGJ) classification, including axial hiatal hernia length, hiatal hernia opening diameter, ...

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Noninvasive Magnetic Therapy Effective in Fecal Incontinence

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Genotype-Guided Dosing Reduces Irinotecan Toxicity

Using UGT1A1 genotype to guide irinotecan dosing curbs severe side effects in patients with impaired metabolism of the drug.

Spyre Says Bowel Disease Drug Cuts Inflammation in Mid-stage Trial

Spyre Therapeutics said on Monday its experimental bowel disease drug met the main goal ⁠of significantly reducing disease severity in a mid-stage trial.

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A small study finds that pre-resection pelvic MRI overstages more than 40% of large rectal polyps in patients referred for endoscopic resection.

A novel noninvasive magnetic therapy is effective, safe, and well tolerated in patients with fecal incontinence, reducing symptom burden and disease severity.

Using UGT1A1 genotype to guide irinotecan dosing curbs severe side effects in patients with impaired metabolism of the drug.

Spyre Therapeutics said on Monday its experimental bowel disease drug met the main goal ⁠of significantly reducing disease severity in a mid-stage trial.

The EMA has reinforced enhanced liver surveillance for a vasculitis therapy after cases of severe and sometimes fatal drug-induced liver injury and vanishing bile duct syndrome.

Kumar Ajit spent more than a week calling dozens of pharmacies in India before he tracked down the platinum-based cancer drug cisplatin his 70-year old mother needed to...

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Pancreatic Cysts: What’s the Actual Cancer Risk?

Pancreatic cysts are common and usually considered low risk — but even those lesions signal a significantly elevated and sustained cancer risk.

UTI Treatment Shift: Is Nitrofurantoin Coming Out on Top?

A large Spanish trial reports higher cure rates with 5-day nitrofurantoin therapy than with fosfomycin or pivmecillinam in women with uncomplicated UTIs.

Takeda Engaged in Antitrust Scheme to Delay Generic Constipation Drug, US Jury Finds

A U.S. jury on Monday found Takeda Pharmaceutical liable for causing about $885 million in damages by delaying a generic version of its constipation drug Amitiza through an...

Blood Proteins Link Poor Sleep to Increased Cancer Risk

Suboptimal sleep health, reflected in low sleep proteomic scores, is consistently associated with an increased risk for cancer, particularly gastrointestinal malignancies.

Housing Instability Tied to Lower Rates of CRC Screening

Unmet health-related social needs, especially housing instability and transportation barriers, are linked to lower rates of screening for colorectal cancer among US adults.

Olanzapine Cuts Radiation-Induced Nausea

The drug, widely used for chemotherapy-related nausea, may also be highly effective for symptoms caused by abdominal-pelvic radiotherapy.

Barrett Esophagus Onset Occurs Decades Before Diagnosis

Molecular clock modeling suggests that the biological onset of Barrett esophagus occurs more than 20 years before the recommended screening age.

Silent Reflux: Clinical Conundrum Solved via Proper Testing

A chronic cough without heartburn are the tell-tale signs of the condition; surgery is typically not the answer.

Zenocutuzumab OK’d for NRG1 Fusion+ Cholangiocarcinoma

The bispecific antibody has previously granted accelerated approval for advanced, unresectable, or metastatic non-small cell lung cancer and pancreatic adenocarcinoma harboring the gene fusions.

Sigmoidoscopy Cuts Colorectal Cancer Risk in Men

Researchers randomly assign more than 100,000 adults without CRC to receive once-only sigmoidoscopy screening or no screening between 1999 and 2001. Here’s what they find.

False Positive mt-sDNA Tests Could Flag Other Cancers

False-positive multi-target stool tests are linked to higher rates of noncolorectal aerodigestive cancers, suggesting further workup may be indicated in these patients.

HER2 Testing in Practice: Case-Based Insights to Improve Interpretation, Reporting, and Multidisciplinary Team Collaboration

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Meeting the Challenge of Accurate and Timely Diagnosis of GEP-NETs

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