The white paper recommends extending endoscopic classification of gastroesophageal junction integrity beyond the slope.

Published Date: 08 Mar 2023

A new white paper from the American Foregut Society expands gastrointestinal tract (EGJ) classification, including axial hiatal hernia length, hiatal hernia opening diameter, ...

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Do High-Risk Features of Prostate Cancer Boost HT Benefit?

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Freeman’s Lobotomy to Deep Brain Stimulation: What Changed?

The history of lobotomy shows the risks for limited evidence and oversight, while modern approaches emphasize targeted treatment, informed consent, and rigorous evaluation.

Wide Variation Seen in Lung Screening False-Positive Rates

US radiologists vary substantially in their reading of low-dose CT lung cancer screens, highlighting a need for measures to help standardize interpretation.

AVD Chemo Regimen Shows Promise in Older Patients With HL

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Do High-Risk Features of Prostate Cancer Boost HT Benefit?

Researchers analyze individual patient data from five randomized phase 3 trials comparing PORT alone vs PORT plus hormone therapy in patients with recurrent prostate cancer.

How Low Does PSA Need to Go in Metastatic Prostate Cancer?

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The U.S. Food and Drug Administration on Monday took steps to increase oversight of food additives as part ⁠of the Trump administration's "Make America Healthy Again"...

The anatomical pattern of inflammatory back pain at disease onset may reveal which patients face a heightened risk for joint complications years later.

Acupuncture was tied to higher response rate, lower symptom severity, and better quality of life in IBS treatment, but doubts about reproducible efficacy remain.

Combining transarterial chemoembolization with subsequent thermal ablation more than doubled PFS and overall survival in patients with liver-confined hepatocellular carcinoma ineligible for curative treatment.

Acting U.S. FDA Commissioner Kyle Diamantas said on Tuesday Americans should feel confident in eating fresh produce, as the agency has finalized guidance for proper...

Funding to tackle acute malnutrition in parts of Somalia has dropped by more than 80% this year, Médecins Sans Frontières said on Tuesday, even though one in every four...

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Etrasimod Effective As First-Line Advanced UC Therapy

Etrasimod can be an effective and safe first-line advanced therapy option in patients with ulcerative colitis who escalate after conventional treatment failure.

Does Doublet Chemotherapy Improve Survival in Rectal Cancer?

Patients with high-risk locally advanced rectal cancer were randomly assigned to receive doublet-LC TNT or conventional neoadjuvant chemoradiotherapy.

Radiation Boost Linked to Better Survival in Rectal Cancer

A phase 2 trial finds that adding a modest radiation boost improves 9-year survival without increasing toxicity, despite no improvement in pathologic complete response.

Creatinine Assay Bias Affects MELD Scoring

Bilirubin interference in commonly used creatinine assays artificially inflates MELD scores in liver transplant candidates, a study reports.

EHR Marker May Help Curb Risk for Liver Transplant Rejection

A remote intervention aimed at improving medication adherence may reduce organ rejection in liver transplant recipients at high risk.

Altimmune Drug Cuts Heavy Drinking in Mid-stage Trial for Alcohol Use Disorder

Altimmune said on Tuesday its experimental drug helped patients with alcohol use disorder cut back on heavy drinking ⁠in a mid-stage trial, sending the company's shares 10%...

Newer Antibiotics Show No Clear Benefit for Staph Infections

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FDA Approves Freenome's Blood Test for Colorectal Cancer Screening

The U.S. FDA has approved Freenome's blood-based colorectal cancer screening test for older adults, paving the way ⁠for partner Abbott to launch it in the U.S. this fall,...

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U.S. produce supplier Taylor Farms complained to White House and Food and Drug Administration officials about the government's inspection process earlier this month, a...

Poultry Firm Recalls Nearly 1.6 Million Dozen Eggs Over Salmonella Risk, FDA Says

The U.S. FDA said on Wednesday that Midwest Poultry Services is recalling nearly 1.6 ⁠million dozen eggs produced in Texas due to potential Salmonella...

CRC Screening in Adults Under 50: Research Reveals Trends

After colorectal cancer screening guidelines were updated in 2021 to lower the screening age to 45, three studies look at how providers are reaching those patients.

Simple Risk Score Is the Best at Detecting Liver Fibrosis

The LiverRisk score outperformed the fibrosis-4 index for detecting moderate or greater fibrosis across all age groups, particularly in younger adults.

How to Predict Iron Therapy Response in IBD

Hepcidin and ferritin-based indices help identify patients with active inflammatory bowel disease who are less likely to respond to iron therapy.

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Anxiety May Undermine Treatment Response in Some GERD Cases

Higher anxiety is linked to poorer response to proton pump inhibitor treatment among patients with gastroesophageal reflux disease.

Older Adults Have Worse Lower GI Bleeding Outcomes

Older adults with lower gastrointestinal bleeding present with more severe disease and substantially higher 30-day mortality—yet most deaths stem not from bleeding itself, but from decompensation of underlying chronic conditions.

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