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Quiz on Targeted Therapy for GISTs: Are You Familiar with the Latest Treatment Strategies?

Dear doctors, participate in this fun and exciting quiz on targeted therapy for GISTs. Targeted therapy for gastrointestinal stromal tumors (GISTs) focuses on inhibiting specific molecular pathways involved in tumor growth. Recent advancements include novel tyrosine kinase inhibitors and combination therapies aimed at overcoming resistance and improving patient outcomes. Participate now.

1. Which of the following tyrosine kinase inhibitors is considered a first-line treatment for GISTs?

2. What is the primary mechanism of action of imatinib in the treatment of GISTs?

3. In cases of imatinib resistance in GISTs, which mutation is commonly associated with decreased drug efficacy?

4. Which second-line therapy is often used for GISTs that progress despite treatment with imatinib?

5. What is the role of molecular testing in the management of GISTs?

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