Congenital melanocytic nevi (CMN) are moles that are present at birth or appear shortly after birth. They are caused by an overgrowth of melanocytes, which are the cells that give skin its color. While CMN can occur anywhere on the body, they are most commonly found on the face, scalp, and neck. Although CMN are typically harmless, they can be associated with an increased risk of developing melanoma, a potentially deadly skin cancer. Therefore, understanding the risk factors, diagnosis, and management of CMN is essential for doctors and other healthcare providers.
Congenital melanocytic nevi come in a variety of shapes and sizes. They can be classified into three categories based on their size and depth: small (less than 1.5 cm in diameter), medium (1.5 to 20 cm in diameter), and large (more than 20 cm in diameter). Small CMN are typically flat and can be mistaken for freckles. Medium CMN are raised and may contain hair follicles. Large CMN are raised and may be pigmented.
There are several risk factors associated with the development of CMN. These include maternal age, family history, and exposure to ultraviolet (UV) radiation. Maternal age has been linked to an increased risk of CMN, with the risk increasing after the age of 30. A family history of CMN also increases the risk of developing the condition. Finally, exposure to UV radiation has been linked to an increased risk of CMN, as UV radiation is known to stimulate melanocyte growth.
The diagnosis of CMN is typically made through physical examination. During the exam, the doctor will look for any moles that are present at birth or that have appeared shortly after birth. The size, shape, and color of the mole will be noted. If the doctor suspects CMN, they may order a biopsy to confirm the diagnosis.
The management of CMN depends on the size, location, and risk factors associated with the mole. Small CMN that are not located on the face or scalp typically do not require any treatment. Medium and large CMN, especially those located on the face and scalp, may require treatment to reduce the risk of melanoma. Treatment options include surgical excision, laser therapy, and topical medications.
Congenital melanocytic nevi are moles that are present at birth or appear shortly after birth. While they are typically harmless, they can be associated with an increased risk of developing melanoma. Therefore, it is important for doctors and other healthcare providers to understand the risk factors, diagnosis, and management of CMN. By doing so, they can help to reduce the risk of developing melanoma in patients with CMN.
1.
Study recommends new grading system for invasive squamous cell carcinoma of the lung
2.
Bayer is transforming pharmaceutical research into women's health
3.
Ineffective medication can remove the "worst fear" of schizophrenia.
4.
Tumor infiltration of major blood vessels, not metastasis, may be primary cause of cancer death
5.
A healthier lifestyle after bowel screening shown to prevent bowel cancer
1.
Oncology Partnerships: Driving Innovation Through Strategic Collaborations and Pharma Engagement USA
2.
Beyond the Tumor: Emerging Frontiers in Cancer Systems Biology
3.
Everything You Need To Know About Splenic Infarction – Symptoms, Treatments, And Prevention
4.
Antibody-Drug Conjugates in Oncology: Breakthroughs, Clinical Updates, and Pipeline Innovation
5.
Understanding Leiomyoma: Causes, Symptoms, and Treatment Options
1.
International Lung Cancer Congress®
2.
Genito-Urinary Oncology Summit 2026
3.
Future NRG Oncology Meeting
4.
ISMB 2026 (Intelligent Systems for Molecular Biology)
5.
Annual International Congress on the Future of Breast Cancer East
1.
Current Scenario of Blood Cancer- A Conclusion on Genomic Testing & Advancement in Diagnosis and Treatment
2.
Updates on Standard V/S High Risk Myeloma Treatment
3.
Breaking Ground: ALK-Positive Lung Cancer Front-Line Management - Part V
4.
Key Takeaways from The CROWN Trial For ALK + NSCLC Patients with CNS Diseases
5.
Should We Use DARA Up Front As First-Line Therapy in MM? - Part II
© Copyright 2025 Hidoc Dr. Inc.
Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation