Understanding Nephrotic vs Nephritic Syndrome: What You Need To Know

Author Name : Dr. PRIYA RUNWAL

Nephrology

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Nephrotic and nephritic syndrome may sound like two similar conditions at first, but they’re actually quite different. Nephrotic syndrome is an umbrella term used to describe a range of kidney diseases that affect the kidneys’ ability to filter proteins from the blood. Nephritic syndrome is an inflammatory disorder that affects the glomeruli, small filters in the kidneys that help filter waste out of the blood. For medical professionals, it's important to understand the distinctions between these two syndromes in order to accurately diagnose and treat patients. In this blog post, we will discuss what nephrotic and nephritic syndrome are, their causes, symptoms, treatment options, and prognosis. We will also explore how diagnosing one over the other can affect patient care and outcomes.

What is Nephrotic Syndrome?

Nephrotic syndrome is a kidney disorder that causes the body to excrete too much protein in the urine. It can also cause edema, or fluid retention, and high cholesterol levels. The most common cause of nephrotic syndrome is damage to the filters in the kidneys, called glomeruli. This damage can be caused by certain diseases, such as diabetes or lupus, or by certain medications. Treatment for nephrotic syndrome focuses on reducing protein loss and treating the underlying cause.

What is Nephritic Syndrome?

Nephritic syndrome is a kidney disorder that typically results from inflammation of the glomeruli, which are the tiny filters in your kidneys that remove waste and excess water from your blood. The inflammation can be caused by infection, immune system disorders, or other conditions. Nephritic syndrome can lead to kidney damage and failure.

The Difference Between Nephrotic and Nephritic Syndrome

Nephrotic syndrome (NS) and nephritic syndrome (NNS) are separate kidney disorders that have different signs and symptoms. NS is characterized by the loss of large amounts of protein in the urine, which can lead to fluid retention and edema. NNS, on the other hand, is marked by the presence of red blood cells in the urine and is often associated with hypertension. While both conditions can cause renal failure, they require different treatment approaches.

Causes of Nephrotic Syndrome

Nephrotic syndrome is a kidney disorder that causes the body to excrete too much protein in the urine. Protein is important for many bodily functions, including fighting infection and keeping the blood from clotting. When there is too much protein in the urine, it can lead to serious health problems, such as malnutrition, infections, and blood clots.

There are many different causes of nephrotic syndrome, including genetic disorders, autoimmune diseases, and certain medications. In some cases, the cause is unknown. Treatment for nephrotic syndrome focuses on managing the symptoms and preventing complications.

Symptoms of Nephrotic Syndrome

Nephrotic syndrome is a kidney disorder that causes the body to excrete too much protein in the urine. Protein is important for many bodily functions, so when it is lost in the urine, a person can become very ill. The most common symptom of nephrotic syndrome is proteinuria, or excessive protein in the urine. Other symptoms can include:

-Edema (swelling), especially in the face, legs, and abdomen
-Weight gain from fluid retention
-Foamy urine
-High cholesterol levels
- Fatigue
-Increased urination at night

Treatment for Nephrotic Syndrome

There is no one-size-fits-all answer to the question of how best to treat nephrotic syndrome.   In general, however, treatment for nephrotic syndrome typically includes medication to suppress the immune system and help reduce inflammation. In severe cases, where kidney function is threatened, plasma exchange or immunosuppressive therapy may be necessary.

Conclusion

In conclusion, knowing the difference between nephrotic and nephritic syndrome is essential for medical professionals. Being able to accurately diagnose each syndrome will help in providing the appropriate treatment for each patient. Nephrotic Syndrome more commonly affects children while Nephritic Syndrome can affect both adults and children alike. 


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