Today's Updates
Phase 2 VALIANT data show the anti-TSLP receptor antibody sharply reduced exacerbations in patients with high eosinophil counts.
Guy Brusselle, MD, PhD, explains why broader cytokine blockade with dupilumab outpaced omalizumab, and why nonremitters in EVEREST still improved.
Exploratory extracellular vesicle biomarkers suggested KP405, a brain-penetrant GLP-1/GIP agonist, engaged insulin signaling and neuroinflammation pathways in a small phase 1 study.
Late-breaking findings from MDS 2026 suggest a gluten-free diet may affect cognitive and quality-of-life measures in Parkinson disease, although no significant changes in motor function were observed.
Seven investigational cerebral palsy therapies—from baby-tooth stem cells to cannabinoids and botulinum toxin—show mixed early results, highlighting key clinical trial milestones ahead.
Benjamin Walter, MD, MBA, discusses how advances in biomarker testing and genetic characterization are informing Parkinson disease care, alongside developments in adaptive deep brain stimulation and efforts to identify disease earlier.
At a NeurologyLive Clinical Forum in Philadelphia, Jessica D. Schulte, MD, PhD, of NYU Grossman School of Medicine, discussed how earlier recognition and systemic therapy options are changing the treatment paradigm for patients with NF1-associated plexiform neurofibromas.
The associate vice president of clinical research at the Parkinson's Foundation discussed a large-scale replication of rs3115534-G, a noncoding GBA1 variant tied to Parkinson disease in people of African ancestry.
Investigational oral dopamine agonist prodrug boosts good ON-time, cuts OFF-time and dyskinesia, and reduces levodopa in advanced Parkinson disease, as phase 2 begins.
8 Endocrinology Headlines You Missed in Q3 2026
Oncology
Review of cancer-associated thrombosis during noncytotoxic therapy, highlighting mechanisms, management, and clinical guidance for healthcare professionals.
Comprehensive review of strategies for pharmacokinetic optimization in combination cancer therapy for improved clinical outcomes.
Comprehensive review of delayed toxicity monitoring in antibody therapies for clinicians.
A comprehensive review of personalized oncolytic virus combinations in oncology, highlighting mechanisms, clinical evidence, and practical guidance.
Dr. Harish P and 1 more
Dr. Vijay Agarwal and 1 more
Dr Suvir Singh
Dr Vijay Agarwal and 1 more
Dr. Todd Bauer and 1 more
Dr. Poonam Patil and 1 more
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