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Quiz on Cracking KRAS: The New Frontier in Lung & Colorectal Cancer Treatment

Dear Doctors, participate in this exciting and informative quiz on Cracking KRAS: The New Frontier in Lung & Colorectal Cancer Treatment, designed specifically for healthcare professionals. This quiz aims to enhance your understanding of KRAS mutations, their role in cancer progression, and the latest targeted therapies revolutionizing the treatment landscape for lung and colorectal cancer. As these malignancies remain among the most challenging to treat, staying updated on cutting-edge advancements is crucial for improving patient care and outcomes. By participating, you'll reinforce your expertise and gain valuable insights into novel KRAS inhibitors, ongoing clinical trials, and evolving treatment strategies. Let’s explore key concepts and clinical applications to ensure we stay at the forefront of precision oncology. Participate now!

1. Which KRAS mutation subtype is most commonly found in non-small cell lung cancer (NSCLC)?

2. What is the mechanism of action of KRAS G12C inhibitors, such as sotorasib and adagrasib?

3. Why has targeting KRAS mutations been historically challenging in cancer therapy?

4. Which KRAS mutation subtype is commonly found in colorectal cancer and is resistant to EGFR inhibitors?

5. Which combination strategy is currently under investigation to overcome resistance to KRAS inhibitors?

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