TRPM3 Antagonist BHV-2100 Shows Safe Profile as Potential Therapy for Migraine

Published Date: 15 Aug 2024

The drug showed a highly favorable pharmacokinetic profile, with maximal concentrations (Tmax) achieved within 1.5 to 2 hours and a mean terminal elimination half-life ranging between 8 to 12 hours.

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Todays Updates

EMA Backs Breast Cancer SERD After FDA No Vote

The recommendation follows phase 3 data showing longer progression-free survival when patients switched to camizestrant plus a CDK4/6 inhibitor.

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The antibody drug conjugate was approved by the FDA for certain patients with triple-negative breast cancer.

Latest News

Pediatric mental health visits in primary care surged over a 9-year period.

Electroacupuncture was associated with long-term efficacy in improving cognitive function compared to sham treatment in patients with Alzheimer’s disease, a new trial shows.

Undiagnosed dementia is highly prevalent in the US and Brazil and is linked to increased 4-year mortality in both countries, a large cohort study shows.

Coffee consumption is associated with improved executive function in patients with early Parkinson’s disease, while smoking has no impact, a new study suggests.

New research suggests a single high dose of psilocybin alters neural activity and may trigger lasting structural brain changes tied to improved well-being.

Targeted intra-arterial cooling delivered during clot retrieval significantly increases functional independence after large-vessel ischemic stroke, with no added risk.

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CTAD: Clinical Trials on Alzheimer's Disease Conference

The New Standard in Multiple Sclerosis: Integrating Evolving Treatment Evidence and Biomarkers to Target Progression

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Decoding Multifocal Motor Neuropathy: A Practical Guide to Diagnosis, Pathogenesis, and Emerging Innovations in Treatment

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AAN: American Academy of Neurology

ISC: International Stroke Conference

CTAD Video Pearls: Video Pearls from the Clinical Trials on Alzheimer's Disease Conference

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Rat Lungworm Is Now in My State. Is It in Yours Too?

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Severe Malaria in Kids Linked to Certain Cognitive, Academic Deficits Years Later

Impairment persisted after episodes of cerebral malaria or severe malarial anemia

Novel Agent Reduces Seizures in Treatment-Resistant Epilepsy

Adjunctive azetukalner cut monthly focal onset seizure frequency by 53% in phase III study

Suppressing a Sneeze May Have Led to Cerebrospinal Fluid Leak

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Investigational treatment improves outcomes without complete complement blockade

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