Glucarpidase Improves Outcomes in Methotrexate-Associated AKI

Published Date: 10 Jan 2025

Treatment tied to higher recovery odds and faster time to kidney recovery

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Trappsol Cyclo Misses Primary End Point in Phase 3 Trial for Niemann-Pick Disease Type C Isabella Ciccone, MPH

Findings from the phase 3 TransportNPC study showed that Trappsol Cyclo missed the primary end point in Niemann-Pick type C, but subgroup and survival data support planned 2026 NDA.

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A joint ESC/ERA guideline on universal CKD screening headlines August 2026's nephrology news, alongside new finerenone and sibeprenlimab trial data.

— Anti-CD20 agent obinutuzumab (Gazyva) gets green light for patients as young as 2 years
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Atacicept Cuts IgAN Progression Risk 76% in ORIGIN 3 Final Data Alex Hillenbrand

Atacicept also stabilized eGFR and matched placebo on safety, with a full FDA approval filing planned for Q4 2026.
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Inaxaplin Cuts Proteinuria in Broader APOL1 Kidney Disease Population Alex Hillenbrand

Phase 2b AMPLIFIED data show a 42.7% UACR drop in AMKD with modest proteinuria; AMPLITUDE interim data are due early 2027.

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Pediatric Acute Kidney Injury Cases Increased Tenfold Over Past 25 Years

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