Unlocking the Benefits of Trulance: A Guide to Improved Digestive Health

Author Name : Dr. VEERUMAL MAHESH

Pharmacology

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Introduction

The digestive system is an incredibly important part of the body, responsible for breaking down food, absorbing nutrients, and eliminating waste. Unfortunately, digestive health issues are incredibly common, with many people suffering from conditions such as irritable bowel syndrome (IBS), Crohn’s disease, and ulcerative colitis. A medication called Trulance (plecanatide) has been approved by the FDA to help improve digestive health, and this article will discuss how doctors can unlock the benefits of Trulance for their patients.

What is Trulance?

Trulance is a medication that is used to treat adults with chronic idiopathic constipation (CIC) or irritable bowel syndrome with constipation (IBS-C). It is a guanylate cyclase-C agonist, which means that it helps to stimulate the body’s natural production of a hormone called guanylate cyclase-C, which helps to regulate the digestive system. Trulance works by increasing the amount of fluid in the intestines, which helps to soften stools and make them easier to pass.

How Does Trulance Work?

Trulance works by stimulating the guanylate cyclase-C receptors in the digestive system. These receptors are responsible for regulating electrolyte and water balance in the intestines. When Trulance stimulates these receptors, it causes the intestines to secrete more fluids, which helps to soften stools and make them easier to pass.

Benefits of Trulance

The primary benefit of Trulance is that it can help to improve digestive health by relieving symptoms of chronic idiopathic constipation (CIC) and irritable bowel syndrome with constipation (IBS-C). Trulance can help to reduce abdominal pain, bloating, and constipation. It can also help to reduce the frequency of bowel movements, and to improve the consistency of stools.

Who is a Good Candidate for Trulance?

Trulance is primarily used to treat adults with chronic idiopathic constipation (CIC) or irritable bowel syndrome with constipation (IBS-C). It is important to note that Trulance is not recommended for children under the age of 18, as it has not been studied in this age group. It is also not recommended for pregnant or breastfeeding women, as it has not been studied in this population.

Side Effects of Trulance

Like all medications, Trulance can cause side effects. The most common side effects of Trulance are abdominal pain, flatulence, diarrhea, nausea, and headache. It is important to note that these side effects are generally mild and do not last long. However, if any of these side effects become severe or persist, it is important to contact a doctor.

Dosing of Trulance

Trulance is typically taken once daily, with or without food. The recommended dose for adults is 3 mg once daily. It is important to note that Trulance should not be taken more than once daily, as this could increase the risk of side effects.

Conclusion

Trulance is a medication that is used to treat adults with chronic idiopathic constipation (CIC) or irritable bowel syndrome with constipation (IBS-C). It works by stimulating the guanylate cyclase-C receptors in the digestive system, which helps to increase the amount of fluid in the intestines and soften stools. The primary benefit of Trulance is that it can help to improve digestive health by relieving symptoms of CIC and IBS-C. It is important to note that Trulance is not recommended for children under the age of 18, pregnant or breastfeeding women, or those who take more than the recommended dose. Doctors can unlock the benefits of Trulance for their patients by discussing the potential benefits and side effects of the medication, and providing the correct dosing instructions.

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