What Is Sacubitril/Valsartan And How Can It Help Improve Heart Health?

Author Name : Dr. priyanka gupta

Cardiology

Page Navigation

As the world population ages, heart health is becoming an increasingly important issue. Fortunately, there are many treatments available to help manage and improve your cardiovascular health. One of these treatments, sacubitril/valsartan, is prescribed to patients with chronic heart failure or those who have recently suffered a heart attack. But what exactly is sacubitril/valsartan? And how can it help improve your heart health? In this article, we will explore the answers to these questions and more. Read on to learn all about this powerful medication and the benefits it can provide in terms of improving your overall cardiovascular wellbeing.

What is sacubitril/valsartan?

Sacubitril/valsartan (brand name: Entresto) is a combination drug used to treat heart failure. It is a relatively new medication, and was approved by the FDA in 2015.

Sacubitril/valsartan belongs to a class of drugs known as angiotensin receptor-neprilysin inhibitors (ARNI). These drugs work by blocking the action of two enzymes, angiotensin II and neprilysin.

Angiotensin II is a substance that causes blood vessels to narrow, which can lead to increased blood pressure. Neprilysin is an enzyme that breaks down substances such as natriuretic peptides, which are hormones that promote body salt and water balance.

By blocking the action of these two enzymes, sacubitril/valsartan prevents blood vessel narrowing and helps to keep natriuretic peptide levels balanced. This leads to improved heart function and reduced congestion in heart failure patients.

Sacubitril/valsartan is typically used in conjunction with other heart failure medications, such as beta blockers or ACE inhibitors.

How does sacubitril/valsartan work?

Sacubitril/valsartan is a medication used to treat heart failure. It works by inhibiting the enzyme neprilysin, which breaks down the hormones natriuretic peptides (NPs). NPs are important for regulating blood pressure and fluid balance in the body. By inhibiting neprilysin, sacubitril/valsartan increases levels of NPs, which leads to improved blood pressure control and reduced congestion and fluid retention in heart failure patients.

What are the benefits of sacubitril/valsartan?

Sacubitril/valsartan is a medication used to treat heart failure. It is a combination of two drugs: sacubitril, an inhibitor of the neprilysin enzyme, and valsartan, an angiotensin II receptor blocker (ARB). Sacubitril/valsartan has been shown to improve survival in people with heart failure.

The most common side effects of sacubitril/valsartan are headache, diarrhea, nausea, and dizziness. This medication can also cause low blood pressure, which can lead to lightheadedness and fainting.be sure to drink plenty of fluids and avoid standing for long periods of time.

If you have heart failure, sacubitril/valsartan can help improve your condition and increase your survival. This medication is generally well-tolerated, but it is important to be aware of the potential side effects. 

Are there any side effects of sacubitril/valsartan?

Yes, there are some potential side effects associated with sacubitril/valsartan. These include hypotension (low blood pressure), headache, fatigue, and diarrhea. However, these side effects are typically mild and generally go away after a few days of taking the medication.

How to take sacubitril/valsartan?

Sacubitril/valsartan is a medication used to treat heart failure. It works by inhibiting the production of a hormone called angiotensin II, which can cause the blood vessels to constrict and the heart to work harder. This can lead to an increased risk of heart attack and stroke.

Sacubitril/valsartan is usually taken twice daily, with or without food. The usual starting dose is one tablet, taken twice daily. You should take sacubitril/valsartan regularly to get the most benefit from it.

If you miss a dose of sacubitril/valsartan, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses of sacubitril/valsartan at the same time.

Common side effects of sacubitril/valsartan include headache, dizziness, tiredness, diarrhea, and nausea. These side effects are usually mild and temporary.

Conclusion

Sacubitril/Valsartan is an important new medication for improving heart health in those with chronic conditions. It has been shown to improve outcomes by reducing the risk of death, hospitalizations from worsening heart failure, and even improving patients’ quality of life. This medication can be a very effective treatment for those suffering from chronic heart failure or other cardiovascular illnesses who are looking to reduce their risk of adverse events and lead healthier lives.


Read more such content on @ Hidoc Dr | Medical Learning App for Doctors
Featured News
Featured Articles
Featured Events
Featured KOL Videos

© Copyright 2025 Hidoc Dr. Inc.

Terms & Conditions - LLP | Inc. | Privacy Policy - LLP | Inc. | Account Deactivation
bot