Today's Updates

Solengepras Meets Primary Endpoint in Phase 3 ARISE Trial of Parkinson Disease Marco Meglio
Published Date: 12 Oct 2026

Phase 3 ARISE trial results show solengepras 150 mg significantly reduced OFF time and improved motor and non-motor symptoms in Parkinson disease.

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Upadacitinib Feasible for Palmoplantar Pustulosis: David Gleeson, BM BCH David Gleeson, BM BCH
Published Date: 12 Oct 2026

Gleeson discusses JAKPPPOT data showing the therapy met all feasibility thresholds with a markedly larger response than historic placebo in PPP.

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Nemolizumab Sustains Atopic Dermatitis Skin, Itch Control Through 3 Years
Published Date: 12 Oct 2026

Nemolizumab Sustains Atopic Dermatitis Skin, Itch Control Through 3 Years

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Atopic Dermatitis Pipeline and Remibrutinib Approval for Dermographism
Published Date: 12 Oct 2026

Atopic Dermatitis Pipeline and Remibrutinib Approval for Dermographism

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Latest News

Two Symptoms Linked to Antibiotic Delays in Presumed Sepsis

— GI and respiratory symptoms at presentation both flagged in observational study

Exercise and Cancer Survival; COVID Vaccine and Immune Checkpoint Inhibitors

— Also in TTHealthWatch: colonoscopy after polyp removal

BPAP Intervention Flops in Asthma Study

Goal of decreasing the duration of beta-agonist therapy in the ED showed no significant effect

To Face Scrutiny at ESC: Statins for the Elderly, New Heart Attack Therapies

STAREE trial will give its verdict on primary prevention statins in people ages 70 and up

Radio Silence on Mitch McConnell's Health Persists

84-year-old senator hasn't been seen in public since his hospitalization nearly 3 months ago

Cefepime Tied to Higher Mortality Odds vs Other Beta-Lactams

The danger may be in the dosing, not in the drug itself

Real-World U.S. Data Back Azithromycin After Unscheduled C-Sections

Postpartum infection rates decreased after landmark 2016 study

Study Warns on Multidrug-Resistant Yeast on Hospital Workers' Gloves, Gowns

C. auris transfer rates topped those of more familiar pathogens

Study Flags RSV Deaths in Kids Not Eligible for Protection

Mortality was concentrated among older children and teens with medical complexity

Cesarean for Early Preterm Births Tied to Maternal Risks

Cesarean delivery for very early preterm births is linked to higher rates of severe maternal complications than vaginal delivery for such cases.

New Blood Tests Fall Short of Replacing Food Challenge

Component testing cuts false positives and cellular assays promise more accuracy, but logistics keep them out of routine practice.

Drug-Induced Lupus: Predicting Systemic Disease Risk

Certain antibodies and systemic symptoms at diagnosis are more frequent in patients with drug-induced subacute cutaneous lupus who develop systemic lupus erythematosus.

Dupilumab May Ease Ear Inflammation in Severe CRSwNP

For patients with severe CRSwNP and concomitant eosinophilic otitis media, dupilumab treatment may provide meaningful benefits over a 12-month period.

Nurse-Led Care Improves Asthma Control in Children

Nurse-led asthma care improves asthma control in children aged 6-12 years in primary care in a study.

Immunotherapy in NSCLC: How Much Is Enough?

Immunotherapy has moved from a last-resort option in NSCLC to a fixture at nearly every stage of the disease, but there's a gap between what the trials tested and how it's actually being used.

What Thriving Hospitalists Know About Building Careers

The still-evolving specialty offers advantages for physicians.

Latest News

Two Symptoms Linked to Antibiotic Delays in Presumed Sepsis

— GI and respiratory symptoms at presentation both flagged in observational study

Exercise and Cancer Survival; COVID Vaccine and Immune Checkpoint Inhibitors

— Also in TTHealthWatch: colonoscopy after polyp removal

BPAP Intervention Flops in Asthma Study

Goal of decreasing the duration of beta-agonist therapy in the ED showed no significant effect

To Face Scrutiny at ESC: Statins for the Elderly, New Heart Attack Therapies

STAREE trial will give its verdict on primary prevention statins in people ages 70 and up

Radio Silence on Mitch McConnell's Health Persists

84-year-old senator hasn't been seen in public since his hospitalization nearly 3 months ago

Cefepime Tied to Higher Mortality Odds vs Other Beta-Lactams

The danger may be in the dosing, not in the drug itself

Real-World U.S. Data Back Azithromycin After Unscheduled C-Sections

Postpartum infection rates decreased after landmark 2016 study

Study Warns on Multidrug-Resistant Yeast on Hospital Workers' Gloves, Gowns

C. auris transfer rates topped those of more familiar pathogens

Study Flags RSV Deaths in Kids Not Eligible for Protection

Mortality was concentrated among older children and teens with medical complexity

Cesarean for Early Preterm Births Tied to Maternal Risks

Cesarean delivery for very early preterm births is linked to higher rates of severe maternal complications than vaginal delivery for such cases.

New Blood Tests Fall Short of Replacing Food Challenge

Component testing cuts false positives and cellular assays promise more accuracy, but logistics keep them out of routine practice.

Drug-Induced Lupus: Predicting Systemic Disease Risk

Certain antibodies and systemic symptoms at diagnosis are more frequent in patients with drug-induced subacute cutaneous lupus who develop systemic lupus erythematosus.

Dupilumab May Ease Ear Inflammation in Severe CRSwNP

For patients with severe CRSwNP and concomitant eosinophilic otitis media, dupilumab treatment may provide meaningful benefits over a 12-month period.

Nurse-Led Care Improves Asthma Control in Children

Nurse-led asthma care improves asthma control in children aged 6-12 years in primary care in a study.

Immunotherapy in NSCLC: How Much Is Enough?

Immunotherapy has moved from a last-resort option in NSCLC to a fixture at nearly every stage of the disease, but there's a gap between what the trials tested and how it's actually being used.

What Thriving Hospitalists Know About Building Careers

The still-evolving specialty offers advantages for physicians.

News All Time

Discordant Tissue Findings in Suspected HLH

Hemophagocytic lymphohistiocytosis is a hyperinflammatory syndrome characterized by an exaggerated immune response to a triggering stimulus.

What Extreme Athletes Teach Us About Sleep Deprivation

What can a 1000-mile race teach MDs about sleep? Dr Alison Kole shares sleep deprivation insights from ultramarathon racing and gives practical tips for exhausted patients.

Omalizumab May Ease Inflammation in Chronic Urticaria

In patients with antihistamine-resistant chronic spontaneous urticaria, omalizumab treatment is linked to clinical improvement and reduced systemic inflammatory markers and D-dimer levels.

Pediatric Lung Transplantation Enters a New Era

New CFTR modulators are reshaping pediatric lung transplantation, forcing clinicians to rethink when children should be referred and listed.

CVS Health's Aetna to Streamline Cancer Treatment Approvals

CVS Health's Aetna health insurance unit will cut back next year on the preapprovals it requires for treatment ⁠for cancer patients to only one medical prior authorization...

Diphtheria Debate Exposes Health Misinformation

A diphtheria death in Sicily has reignited debate over vaccines, migration, and how political spin can distort public health facts.

Azithromycin Use Cuts Cesarean Infections

Azithromycin has been shown to lower the risk for postoperative infection during cesarean deliveries when added to more standard prophylactics such as cefazolin.

Methotrexate for IBD: How Do GIs Use It?

A new study offers the most comprehensive real-world look yet at methotrexate use in treating IBD in everyday practice.

AI Digital Twins Get Better and Better: Cancer in Crosshairs

Digital twins allow doctors to simulate treatment to see what will work best — and the tech has made real strides in cardiology. Oncology remains the bigger challenge.

S1P Modulators: 5 Agents, One Safety Playbook

Five S1P modulators now span neurology and GI. Bruce Cree, MD, PhD, and others weigh in on why selectivity differences are no longer academic.

As-Needed Allergic Rhinitis Meds Comparable to Daily Use

Patients with allergic rhinitis who use medication as needed can achieve symptom control and treatment satisfaction comparable to those achieved by patients who use them daily.

Host-Directed Therapies and Phages in Lung Care

Host-directed and phage therapies are emerging as alternatives to antibiotics in managing lung infections in a worsening antimicrobial resistance crisis.

Mild Brain Injury Frequently Missed in the ED

Only 21% of adults with closed head injury have mTBI diagnosed or clinically suspected in the ED, despite 41% meeting diagnostic criteria, with missed diagnoses most common among middle-aged adults.

D10 Matches D50 for Hypoglycemia, Shows Lower Rebound Risk

A lower-concentration dextrose solution matches the standard treatment for hypoglycemia in the emergency department but carries a lower risk for rebound hypoglycemia.

A Rare Hearing Implant Bypasses Damaged Nerves

When cochlear implants failed, doctors turned to a brainstem auditory implant to restore sound awareness in a patient with profound deafness.

Two-Midnight Rule: Key Strategies for Observation Patients

The Two-Midnight Rule has created important clinical and operational strategies for hospitals.

Recommended News For You

'Converging' Evidence of Link Between Air Pollution and Breast Cancer

AI-based liquid biopsy shows promise for detecting brain cancer

Reasons Behind Refusing Stem Cell Transplantation in Certain Myeloma Patients.

Dr. Prerana S. Nesargi's message for Childhood Cancer Awareness Month 2023 is to increase understanding of pediatric oncology.

Updates from the 2022 WHO classification of kidney epithelial tumors

Cancer cells with thick glycocalyx barrier evade immune system better: study

Defibrotide Prophylaxis May Reduce SOS Risk After HSCT

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